Search Results - "Muzumdar, Sukalp"
-
1
Nrf3 promotes UV-induced keratinocyte apoptosis through suppression of cell adhesion
Published in Cell death and differentiation (01-11-2018)“…The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) is a key regulator of the cellular stress response, but the biological functions of…”
Get full text
Journal Article -
2
ERBB2 Is Essential for the Growth of Chemically Induced Skin Tumors in Mice
Published in Journal of investigative dermatology (01-04-2017)“…Although the epidermal growth factor receptor has established roles in skin carcinogenesis, inflammation, and wound healing, the functions of the structurally…”
Get full text
Journal Article -
3
Nrf2-Mediated Expansion of Pilosebaceous Cells Accelerates Cutaneous Wound Healing
Published in The American journal of pathology (01-03-2019)“…The nuclear factor (erythroid-derived 2)–like 2 (Nrf2) transcription factor is a key regulator of the cellular stress response. Therefore, pharmacologic Nrf2…”
Get full text
Journal Article -
4
Nrf2 Activation Promotes Keratinocyte Survival during Early Skin Carcinogenesis via Metabolic Alterations
Published in Cancer research (Chicago, Ill.) (15-11-2015)“…Pharmacologic activation of the transcription factor NRF2 has been suggested to offer a strategy for cancer prevention. In this study, we present evidence from…”
Get full text
Journal Article -
5
Large-Scale Quantitative Proteomics Identifies the Ubiquitin Ligase Nedd4-1 as an Essential Regulator of Liver Regeneration
Published in Developmental cell (25-09-2017)“…The liver is the only organ in mammals that fully regenerates even after major injury. To identify orchestrators of this regenerative response, we performed…”
Get full text
Journal Article -
6
Genetic activation of Nrf2 reduces cutaneous symptoms in a murine model of Netherton syndrome
Published in Disease models & mechanisms (01-06-2020)“…Netherton syndrome is a monogenic autosomal recessive disorder primarily characterized by the detachment of the uppermost layer of the epidermis, the It…”
Get full text
Journal Article -
7
First person – Sukalp Muzumdar
Published in Disease models & mechanisms (01-05-2020)“…First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career…”
Get full text
Journal Article -
8
A granular view of X-linked chronic granulomatous disease exploiting single-cell transcriptomics
Published in The Journal of immunology (1950) (01-05-2022)“…X-linked chronic granulomatous disease (X-CGD) is a rare monogenetic immunodeficiency primarily affecting phagocytes. Precipitated by mutations in the CYBB…”
Get full text
Journal Article -
9
Correction to: Nrf3 promotes UV-induced keratinocyte apoptosis through suppression of cell adhesion
Published in Cell death and differentiation (2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text
Journal Article -
10
Autocrine and Paracrine Regulation of Keratinocyte Proliferation through a Novel Nrf2-IL-36γ Pathway
Published in The Journal of immunology (1950) (01-06-2016)“…The Nrf2 transcription factor is well known for its cytoprotective functions through regulation of genes involved in the detoxification of reactive oxygen…”
Get full text
Journal Article -
11
Conserved cell‐type specific signature of resilience to Alzheimer’s disease nominates role for excitatory cortical neurons
Published in Alzheimer's & dementia (01-12-2022)“…Background Alzheimer’s disease (AD), the leading cause of dementia, affects millions of people worldwide. With no disease‐modifying medication currently…”
Get full text
Journal Article -
12
ERBB3 is required for tumor promotion in a mouse model of skin carcinogenesis
Published in Molecular oncology (01-11-2015)“…The epidermal growth factor receptor (EGFR) plays a key role in skin inflammation, wound healing, and carcinogenesis. Less is known about the functions of the…”
Get full text
Journal Article -
13
Understanding the functional discrepancy of Pim-1 in cancer
Published in Frontiers in bioscience (Elite edition) (01-01-2015)“…The Pim-1 gene encodes for a proto-oncogenic serine/threonine protein kinase and is generally involved in cytokine signaling as well as in various signaling…”
Get more information
Journal Article -
14
Genetic activation of Nrf2 reduces cutaneous symptoms in a murine model of Netherton syndrome
Published in Disease models & mechanisms (01-01-2020)“…Netherton syndrome is a monogenic autosomal recessive disorder primarily characterized by the detachment of the uppermost layer of the epidermis, the stratum…”
Get full text
Journal Article -
15
ADF Winter School—An exciting concept of the Arbeitsgemeinschaft Dermatologische Forschung to connect young scientists and clinician scientists in Dermatology at the top of Germany
Published in Experimental dermatology (01-03-2017)Get full text
Journal Article Conference Proceeding