Influence of platelet activation factor and prostaglandins on cholesterol esterification in human plasma

Prostaglandin E 1 (PGE 1) and platelet activation factor (PAF) were found respectively to activate or to inhibit cholesterol esterification in whole plasma but not in lipoprotein-deficient plasma. It is suggested that these effects are mediated by the interaction of PGE 1 and PAF with high-density l...

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Bibliographic Details
Published in:	FEBS letters Vol. 190; no. 2; pp. 305 - 306
Main Authors:	Bergelson, L.D., Kulikov, V.I., Muzia, G.I.
Format:	Journal Article
Language:	English
Published:	Amsterdam Elsevier B.V 14-10-1985 Elsevier
Subjects:	Alprostadil - pharmacology Applied sciences Biological and medical sciences Cholesterol Esters - blood Exact sciences and technology Fundamental and applied biological sciences. Psychology HDL, high-density lipoproteins Humans LCAT, lecithin : cholesterol-acyltransferase Lipids. Glycolipids Lipoproteins - deficiency Metabolisms and neurohumoral controls Other techniques and industries PAF, platelet activation factor, 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine PG, prostaglandin Platelet Activating Factor - pharmacology Prostaglandins - pharmacology Vertebrates: anatomy and physiology, studies on body, several organs or systems LCAT, lecithin : cholesterol-acyltransferase PAF, platelet activation factor, 1-alkyl-2-acetyl- sn-glycero-3-phosphocholine PG, prostaglandin HDL, high-density lipoproteins Human Prostaglandin Metabolism Arachidonic acid derivatives Cholesterol Platelet activating factor
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Summary:	Prostaglandin E 1 (PGE 1) and platelet activation factor (PAF) were found respectively to activate or to inhibit cholesterol esterification in whole plasma but not in lipoprotein-deficient plasma. It is suggested that these effects are mediated by the interaction of PGE 1 and PAF with high-density lipoproteins [(1984) FEBS Lett. 173, 291-294]. Possible physiological implications of these findings are discussed. Platelet activating factor High density lipoprotein Cholesterol esterification
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0014-5793 1873-3468
DOI:	10.1016/0014-5793(85)81306-5