Search Results - "Muyey, Daniel muteb"
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Baicalein attenuates oxidative damage in mice haematopoietic cells through regulation of PDGFRβ
Published in Molecular and cellular probes (01-08-2024)“…Platelet-derived growth factor receptor β (PDGFRβ) plays a crucial role in murine haematopoiesis. Baicalein (BAI), a naturally occurring flavonoid, can…”
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The impact of DNMT3A variant allele frequency and two different comutations on patients with de novo cytogenetically normal acute myeloid leukemia
Published in Cancer medicine (Malden, MA) (01-05-2023)“…To refine the biological and prognostic significance of DNMT3A mutations in acute myeloid leukemia (AML), we assessed the impact of DNMT3A variant allele…”
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A germline JAK2 exon12 mutation and a late somatic CALR mutation in a patient with essential thrombocythemia
Published in Frontiers in oncology (04-01-2024)“…It has been discovered that Janus kinase 2 ( ) exon12 mutations lead to the polycythemia vera (PV) phenotype, while somatic mutations of calreticulin ( ) are…”
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The characteristics and clinical prognosis analysis of ASXL1 mutations in Chinese adult patients with primary cytogenetically normal acute myeloid leukemia by next-generation sequencing
Published in Leukemia & lymphoma (24-08-2022)“…We analyzed 156 adult patients with primary cytogenetically normal AML for ASXL1 mutations and co-mutations using targeted next-generation sequencing with a…”
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The clinical characteristics and prognosis of Chinese acute myeloid leukemia patients with CSF3R mutations
Published in International journal of laboratory hematology (01-04-2022)“…Introduction The colony‐stimulating factor 3 receptor (CSF3R) controls the proliferation of myeloid progenitors and differentiation into neutrophils. However,…”
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GATA2 rs2335052 and GATA2 rs78245253 single‐nucleotide polymorphisms in Chinese patients with acute myelocytic leukemia
Published in International journal of laboratory hematology (01-12-2021)“…Introduction GATA binding protein 2 (GATA2) gene, involved in progression of hematologic malignancies and various solid tumors, is a susceptibility gene for…”
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NRAS mut DNMT3A mut Clone Identifies a Subset of de novo Cytogenetically Normal Acute Myeloid Leukemia with Adverse Prognosis
Published in Annals of clinical and laboratory science (01-05-2023)“…To investigate the molecular characteristics and clinical prognosis of the neuroblastoma RAS viral oncogene (NRAS) in patients with primary cytogenetically…”
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BCR/ABL1ΔE7‐8‐9 isoform contributes to tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Published in Hematological oncology (01-12-2022)“…In chronic myeloid leukemia (CML) patients, the involvement of the BCR/ABL1 isoform in tyrosine kinase inhibitors (TKIs) resistance has attracted lots of…”
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The clinical characteristics and prognosis of cytogenetically normal AML with single mutations of CEBPA
Published in International journal of laboratory hematology (01-12-2021)“…Introduction CEBPA mutation is a common mutation in normal karyotype AML. CEBPAdm AML has been recognized as a separate entity, but there is still controversy…”
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A new pathway for the transformation of AML in MDS: APA mechanism regulated by NUDT21 and RUNX1
Published in Neoplasma (01-06-2023)“…We have identified that NUDT21 plays a vital role in MDS transformations, while the transcription factor RUNX1 is essential for normal hematopoiesis, which is…”
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