Search Results - "Muwonge, Alecia N."

Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes by Zhong, Yifei, Lee, Kyung, Deng, Yueyi, Ma, Yueming, Chen, Yiping, Li, Xueling, Wei, Chengguo, Yang, Shumin, Wang, Tianming, Wong, Nicholas J., Muwonge, Alecia N., Azeloglu, Evren U., Zhang, Weijia, Das, Bhaskar, He, John Cijiang, Liu, Ruijie

“…Arctigenin (ATG) is a major component of Fructus Arctii , a traditional herbal remedy that reduced proteinuria in diabetic patients. However, whether ATG…”
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LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments by Ge, Xuhua, Zhang, Tao, Yu, Xiaoxia, Muwonge, Alecia N, Anandakrishnan, Nanditha, Wong, Nicholas J, Haydak, Jonathan C, Reid, Jordan M, Fu, Jia, Wong, Jenny S, Bhattacharya, Smiti, Cuttitta, Christina M, Zhong, Fang, Gordon, Ronald E, Salem, Fadi, Janssen, William, Hone, James C, Zhang, Aihua, Li, Hong, He, John C, Gusella, G Luca, Campbell, Kirk N, Azeloglu, Evren U

“…Maintenance of the intricate interdigitating morphology of podocytes is crucial for glomerular filtration. One of the key aspects of specialized podocyte…”
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Nicotine, smoking, podocytes, and diabetic nephropathy by Jaimes, Edgar A, Zhou, Ming-Sheng, Siddiqui, Mohammed, Rezonzew, Gabriel, Tian, Runxia, Seshan, Surya V, Muwonge, Alecia N, Wong, Nicholas J, Azeloglu, Evren U, Fornoni, Alessia, Merscher, Sandra, Raij, Leopoldo

“…Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease. Besides glycemic and blood pressure control, environmental factors such as…”
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Patient-Specific Pharmacokinetics and Dasatinib Nephrotoxicity by Adegbite, Benjamin O, Abramson, Matthew H, Gutgarts, Victoria, Musteata, Florin M, Chauhan, Kinsuk, Muwonge, Alecia N, Meliambro, Kristin A, Salvatore, Steven P, El Ghaity-Beckley, Sebastian, Kremyanskaya, Marina, Marcellino, Bridget, Mascarenhas, John O, Campbell, Kirk N, Chan, Lili, Coca, Steven G, Berman, Ellin M, Jaimes, Edgar A, Azeloglu, Evren U

“…Dasatinib has been associated with nephrotoxicity. We sought to examine the incidence of proteinuria on dasatinib and determine potential risk factors that may…”
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Structure-based methods to predict mutational resistance to diarylpyrimidine non-nucleoside reverse transcriptase inhibitors by Azeem, Syeda Maryam, Muwonge, Alecia N., Thakkar, Nehaben, Lam, Kristina W., Frey, Kathleen M.

“…[Display omitted] •A computational molecular modeling approach was used to evaluate changes in stability and affinity for mutations in HIV RT.•Our approach…”
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Predicting the Effects of GSTPπ Polymorphism on Resistance to Ezatiostat by Risbud, Kajal S., Muwonge, Alecia N., Frey, Kathleen M.

“…Glutathione S‐transferases (GSTs) are a family of phase II metabolic enzymes. These enzymes catalyze the conjugation of glutathione (GSH) to xenobiotic…”
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Exploiting the Components Leading to Mutational Resistance in Rigid and Flexible Non‐nucleoside Reverse Transcriptase Inhibitors (NNRTIs) by azeem, syeda maryam, Muwonge, Alecia N., Ivatarov, Michael, Yunayev, Matatiya, Frey, Kathleen M.

“…Non‐nucleoside reverse transcriptase Inhibitors (NNRTIs) are antiretroviral drugs that bind to an allosteric site in HIV reverse transcriptase (RT). NNRTIs are…”
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