Search Results - "Mutter, Fiona"

Consequences of nano and microplastic exposure in rodent models: the known and unknown by da Silva Brito, Walison Augusto, Mutter, Fiona, Wende, Kristian, Cecchini, Alessandra Lourenco, Schmidt, Anke, Bekeschus, Sander

“…The ubiquitous nature of micro- (MP) and nanoplastics (NP) is a growing environmental concern. However, their potential impact on human health remains unknown…”
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Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress by Mutter, Fiona E, Park, B Kevin, Copple, Ian M

“…Beyond specific limits of exposure, chemical entities can provoke deleterious effects in mammalian cells via direct interaction with critical macromolecules or…”
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Restricted differentiative capacity of Wt1-expressing peritoneal mesothelium in postnatal and adult mice by Wilm, Thomas P., Tanton, Helen, Mutter, Fiona, Foisor, Veronica, Middlehurst, Ben, Ward, Kelly, Benameur, Tarek, Hastie, Nicholas, Wilm, Bettina

“…Previously, genetic lineage tracing based on the mesothelial marker Wt1, appeared to show that peritoneal mesothelial cells have a range of differentiative…”
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Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity by Forootan, Shiva S., Mutter, Fiona E., Kipar, Anja, Iwawaki, Takao, Francis, Ben, Goldring, Christopher E., Park, B. Kevin, Copple, Ian M.

“…The transcription factor Nrf2 coordinates an adaptive response to chemical and oxidative stress characterised by the upregulated expression of cytoprotective…”
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Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury by Copple, Ian M., den Hollander, Wouter, Callegaro, Giulia, Mutter, Fiona E., Maggs, James L., Schofield, Amy L., Rainbow, Lucille, Fang, Yongxiang, Sutherland, Jeffrey J., Ellis, Ewa C., Ingelman-Sundberg, Magnus, Fenwick, Stephen W., Goldring, Christopher E., van de Water, Bob, Stevens, James L., Park, B. Kevin

“…The transcription factor NRF2, governed by its repressor KEAP1, protects cells against oxidative stress. There is interest in modelling the NRF2 response to…”
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Investigation of Nrf2 Activity Measures for Assessing the Toxicological and Pharmacological Effects of Drugs by Mutter, Fiona

“…The transcription factor Nuclear factor erythroid 2-related factor 2 (NRF2) orchestrates the expression of a battery of cytoprotective genes containing…”
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