Search Results - "Muto, Yasutoshi"

Risk factors for vitamin D deficiency in patients with Crohn's disease by Tajika, Masahiro, Matsuura, Akira, Nakamura, Tsuneya, Suzuki, Takashi, Sawaki, Akira, Kato, Tetsuya, Hara, Kazuo, Ookubo, Kenji, Yamao, Kenji, Kato, Masahiko, Muto, Yasutoshi

“…Although the pathogenesis of osteopenia in Crohn's disease is not established, vitamin D deficiency is thought to be an important risk factor. However, little…”
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Retinoids in cancer chemoprevention by Okuno, Masataka, Kojima, Soichi, Matsushima-Nishiwaki, Rie, Tsurumi, Hisashi, Muto, Yasutoshi, Friedman, Scott L, Moriwaki, Hisataka

“…We review the therapeutic and preventive applications of a retinoid analog (vitamin A and its derivatives) for human cancers. Chemoprevention of cancer is an…”
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High Levels of Serum Interleukin-10 and Tumor Necrosis Factor—α Are Associated with Fatality in Fulminant Hepatitis by Nagaki, Masahito, Iwai, Hiroko, Naiki, Takafumi, Ohnishi, Hiroo, Muto, Yasutoshi, Moriwaki, Hisataka

“…Serum pro- and anti-inflammatory mediators in patients with acute liver diseases were assessed to clarify the clinical significance of these measurements in…”
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Perilla oil prevents the excessive growth of visceral adipose tissue in rats by down-regulating adipocyte differentiation by Okuno, M, Kajiwara, K, Imai, S, Kobayashi, T, Honma, N, Maki, T, Suruga, K, Goda, T, Takase, S, Muto, Y, Moriwaki, H

“…We examined the effect of dietary oils with different fatty acid compositions on the growth of visceral adipose tissue in rats. Rats were fed for 4 mo starting…”
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Acyclic retinoid induces partial differentiation, down-regulates telomerase reverse transcriptase mRNA expression and telomerase activity, and induces apoptosis in human hepatoma-derived cell lines by Yasuda, Ichiro, Shiratori, Yoshimune, Adachi, Seiji, Obora, Akihiro, Takemura, Masao, Okuno, Masataka, Shidoji, Yoshihiro, Seishima, Mitsuru, Muto, Yasutoshi, Moriwaki, Hisataka

“…Background/Aims : Acyclic retinoid (AR; all trans -3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid) prevented hepatocarcinogenesis in animal models…”
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Prevention of geranylgeranoic acid-induced apoptosis by phospholipid hydroperoxide glutathione peroxidase gene by Shidoji, Yoshihiro, Okamoto, Kyoko, Muto, Yasutoshi, Komura, Sadaaki, Ohishi, Nobuko, Yagi, Kunio

“…Micromolar concentrations (0.5 ∼ 5 µM) of all‐trans geranylgeranoic acid (GGA) induced cell death in a guinea pig cell line, 104C1, whereas under the same…”
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Effects of Geranylgeranoic Acid in Bone: Induction of Osteoblast Differentiation and Inhibition of Osteoclast Formation by Wang, Xinxiang, Wu, Jian, Shidoji, Yoshihiro, Muto, Yasutoshi, Ohishi, Nobuko, Yagi, Kunio, Ikegami, Sachie, Shinki, Toshimasa, Udagawa, Nobuyuki, Suda, Tatsuo, Ishimi, Yoshiko

“…Retinoids are known to be of special importance for normal bone growth and development. Recently, we reported that retinoids not only induced osteoblast…”
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Rapid Loss in the Mitochondrial Membrane Potential during Geranylgeranoic Acid-Induced Apoptosis by Shidoji, Yoshihiro, Nakamura, Noriaki, Moriwaki, Hisataka, Muto, Yasutoshi

“…A synthetic geranylgeranoic acid (GGA) induced apoptotic cell death in a human hepatoma cell line, HuH-7, but not in mouse primary cultured hepatocytes. Prior…”
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Immunopathogenesis of hepatic fibrosis in chronic liver injury induced by repeatedly administered concanavalin A by Kimura, Kiminori, Ando, Kazuki, Ohnishi, Hiroo, Ishikawa, Tetsuya, Kakumu, Shinichi, Takemura, Masao, Muto, Yasutoshi, Moriwaki, Hisataka

“…Liver fibrosis is commonly observed in chronic liver disease. However, the immunological mechanisms underlying hepatic fibrosis due to chronic inflammation are…”
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Regulation of Cell Cycle-Related Genes in Rat Hepatocytes by Transforming Growth Factor β1 by Sugiyama, Akihiko, Nagaki, Masahito, Shidoji, Yoshihiro, Moriwaki, Hisataka, Muto, Yasutoshi

“…Transforming growth factor β (TGF-β) is a potent inhibitor of the proliferation of many cell types. We investigated the effects of TGF-β1 on cyclin D1, cyclin…”
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Preferential Use of Branched-Chain Amino Acids as an Energy Substrate in Patients with Liver Cirrhosis by KATO, Masahiko, MIWA, Yoshiyuki, TAJIKA, Masahiro, HIRAOKA, Tetsuya, MUTO, Yasutoshi, MORIWAKI, Hisataka

“…We analyzed basal energy metabolism in 20 healthy volunteers and 41 cirrhotic patients by indirect calorimetry. Subjects were then given either glucose,…”
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Suppressing effect of perilla oil on azoxymethane-induced foci of colonic aberrant crypts in rats by Onogi, Nobuhito, Okuno, Masataka, Komaki, Chihito, Moriwaki, Hisataka, Kawamori, Toshihiko, Tanaka, Takuji, Mori, Hideki, Muto, Yasutoshi

“…We have investigated the modulatory effect of dietary perilla oil which is rich in the n-3 polyunsaturated fatty acid, α-linolenic acid, on the development of…”
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Inhibitory Effects of (—)‐Epigallocatechin Gallate on Spontaneous Hepatoma in C3H/HeNCrj Mice and Human Hepatoma‐derived PLC/PRF/5 Cells by Nishida, Hiroshi, Omori, Masahide, Fukutomi, Yasushi, Ninomiya, Mitsuo, Nishiwaki, Shinji, Suganuma, Masami, Moriwaki, Hisataka, Muto, Yasutoshi

“…The inhibitory effect of (—)‐epigallocatechin gallate (EGCG), a main constituent of Japanese green tea, on spontaneous hepatoma in C3H/HeNCrj mice was…”
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In Vitro Study of the Chemopreventive Effects of Chinese Herbs against Hepatocarcinogenesis by Song, Hai Zhen, Igarashi, Miki, Kato, Masahiko, Muto, Yasutoshi

“…The chemopreventive effects of seven Chinese herbs against hepatocarcinogenesis were evaluated in vitro. The water extracts from Scutellaria barbata and…”
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Aberrant metabolism of retinoid X receptor proteins in human hepatocellular carcinoma by Matsushima-Nishiwaki, Rie, Shidoji, Yoshihiro, Nishiwaki, Shinji, Yamada, Tetsuya, Moriwaki, Hisataka, Muto, Yasutoshi

“…A polyclonal antibody was raised against a recombinant ligand binding domain construct of the human retinoid X receptor (RXR)α. This antibody reacted with an…”
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IL-12 induces specific cytotoxicity against regenerating hepatocytes in vivo by Matsushita, Tomomichi, Ando, Kazuki, Kimura, Kiminori, Ohnishi, Hiroo, Imawari, Michio, Muto, Yasutoshi, Moriwaki, Hisataka

“…Although impaired liver regeneration is thought to be a major cause of death in patients with fulminant hepatitis, the mechanisms are not well defined. Since…”
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Ursodeoxycholic acid corrects defective natural killer activity by inhibiting prostaglandin E2 production in primary biliary cirrhosis by NISHIGAKI, Y, OHNISHI, H, MORIWAKI, H, MUTO, Y

“…We evaluated the effect of ursodeoxycholic acid on the defective natural killer activity in primary biliary cirrhosis. Administration of ursodeoxycholic acid…”
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Antiproliferative effect of carotenoids on human colon cancer cells without conversion to retinoic acid by Onogi, Nobuhito, Okuno, Masataka, Matsushima-Nishiwaki, Rie, Fukutomi, Yasushi, Moriwaki, Hisataka, Muto, Yasutoshi, Kojima, Soichi

“…The present study employed two human colon cancer cell lines, DLD-1 and Colo 320DM, to investigate whether the provitamin A activity of carotenoids is…”
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Effects of oral branched-chain amino acid granules on event-free survival in patients with liver cirrhosis by Muto, Yasutoshi, Sato, Shunichi, Watanabe, Akiharu, Moriwaki, Hisataka, Suzuki, Kazuyuki, Kato, Akinobu, Kato, Masahiko, Nakamura, Teiji, Higuchi, Kiyohiro, Nishiguchi, Shuhei, Kumada, Hiromitsu

“…Nutritional intervention with branched-chain amino acid (BCAA) is reported to increase serum albumin concentration in patients with decompensated cirrhosis…”
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Nutritional pharmacotherapy of chronic liver disease: from support of liver failure to prevention of liver cancer by Moriwaki, H, Tajika, M, Miwa, Y, Kato, M, Yasuda, I, Shiratori, Y, Okuno, M, Kato, T, Ohnishi, H, Muto, Y

“…Many patients with liver cirrhosis are in a state of protein and energy malnutrition and require careful nutritional support. Our research has revealed that…”
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