Search Results - "Mutlak, Yara Eid"
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USP1 deubiquitinates Akt to inhibit PI3K‐Akt‐FoxO signaling in muscle during prolonged starvation
Published in EMBO reports (03-04-2020)“…PI3K‐Akt‐FoxO‐mTOR signaling is the central pathway controlling growth and metabolism in all cells. Ubiquitination of the protein kinase Akt prior to its…”
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Journal Article -
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A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size
Published in Nature communications (13-03-2020)“…Signaling through the insulin receptor governs central physiological functions related to cell growth and metabolism. Here we show by tandem native protein…”
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Journal Article -
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Decreased melanoma CSF-1 secretion by Cannabigerol treatment reprograms regulatory myeloid cells and reduces tumor progression
Published in Oncoimmunology (31-12-2023)“…During solid tumor progression, the tumor microenvironment (TME) evolves into a highly immunosuppressive milieu. Key players in the immunosuppressive…”
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The extracellular matrix protein agrin promotes heart regeneration in mice
Published in Nature (London) (13-07-2017)“…The adult mammalian heart is non-regenerative owing to the post-mitotic nature of cardiomyocytes. The neonatal mouse heart can regenerate, but only during the…”
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USP 1 deubiquitinates Akt to inhibit PI 3K‐Akt‐FoxO signaling in muscle during prolonged starvation
Published in EMBO reports (03-04-2020)Get full text
Journal Article