Search Results - "Muthusamy, Karen"

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  1. 1

    Microwave assisted SPPS of amylin and its toxicity of the pure product to RIN-5F cells by Muthusamy, Karen, Albericio, Fernando, Arvidsson, Per I., Govender, Patrick, Kruger, Hendrik G., Maguire, Glenn E. M., Govender, Thavendran

    Published in Biopolymers (2010)
    “…The 37‐amino acid polypeptide islet amyloid polypeptide (IAPP), or amylin, is found as amyloid aggregates in the islets of Langerhans in patients with type II…”
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    Journal Article
  2. 2

    Design and study of peptide-based inhibitors of amylin cytotoxicity by Muthusamy, Karen, Arvidsson, Per I., Govender, Patrick, Kruger, Hendrik G., Maguire, Glenn E.M., Govender, Thavendran

    Published in Bioorganic & medicinal chemistry letters (15-02-2010)
    “…The incidence of type II diabetes is on the increase each year and the World Health Organisation (WHO) predicts there to be over 360 million diabetic patients…”
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  3. 3

    Pentacyclo-undecane derived cyclic tetra-amines: Synthesis and evaluation as potent anti-tuberculosis agents by Onajole, Oluseye K., Govender, Karnishree, Govender, Patrick, van Helden, Paul D., Kruger, Hendrik G., Maguire, Glenn E.M., Muthusamy, Karen, Pillay, Manormoney, Wiid, Ian, Govender, Thavendran

    Published in European journal of medicinal chemistry (01-11-2009)
    “…As part of an ongoing effort to develop highly potent anti-tuberculosis agents, fourteen pentacyclo-undecane (PCU) tetra-amine compounds were synthesized and…”
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    Journal Article