Search Results - "Muthusamy, Karen"
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Microwave assisted SPPS of amylin and its toxicity of the pure product to RIN-5F cells
Published in Biopolymers (2010)“…The 37‐amino acid polypeptide islet amyloid polypeptide (IAPP), or amylin, is found as amyloid aggregates in the islets of Langerhans in patients with type II…”
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Design and study of peptide-based inhibitors of amylin cytotoxicity
Published in Bioorganic & medicinal chemistry letters (15-02-2010)“…The incidence of type II diabetes is on the increase each year and the World Health Organisation (WHO) predicts there to be over 360 million diabetic patients…”
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Pentacyclo-undecane derived cyclic tetra-amines: Synthesis and evaluation as potent anti-tuberculosis agents
Published in European journal of medicinal chemistry (01-11-2009)“…As part of an ongoing effort to develop highly potent anti-tuberculosis agents, fourteen pentacyclo-undecane (PCU) tetra-amine compounds were synthesized and…”
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