Search Results - "Muthunayake, Nisansala S."
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Visualization of gender, race, citizenship and academic performance in association with career outcomes of 15-year biomedical doctoral alumni at a public research university
Published in PloS one (17-05-2018)“…It has long been thought that biomedical doctoral students pursue careers primarily as tenure-track/tenured faculty at research institutions. Recent reports…”
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The BR-body proteome contains a complex network of protein-protein and protein-RNA interactions
Published in Cell reports (Cambridge) (31-10-2023)“…Bacterial ribonucleoprotein bodies (BR-bodies) are non-membrane-bound structures that facilitate mRNA decay by concentrating mRNA substrates with RNase E and…”
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Exposure to multiple career pathways by biomedical doctoral students at a public research university
Published in PloS one (22-06-2018)“…The Broadening Experiences in Scientific Experiences (BEST) program at Wayne State University was designed to increase doctoral students' awareness of multiple…”
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The DEAD-box RNA helicase RhlB is required for efficient RNA processing at low temperature in Caulobacter
Published in Microbiology spectrum (12-12-2023)“…One of the most important control points in gene regulation is RNA stability, which determines the half-life of a transcript from its transcription until its…”
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Differential Centrifugation to Enrich Bacterial Ribonucleoprotein Bodies (BR bodies) from Caulobacter crescentus
Published in STAR protocols (18-12-2020)“…Bacterial RNP bodies (BR bodies) contain the mRNA decay machinery, but the collection of associated RNAs and proteins are poorly defined. Here, we present a…”
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BR-Bodies Provide Selectively Permeable Condensates that Stimulate mRNA Decay and Prevent Release of Decay Intermediates
Published in Molecular cell (21-05-2020)“…Biomolecular condensates play a key role in organizing RNAs and proteins into membraneless organelles. Bacterial RNP-bodies (BR-bodies) are a biomolecular…”
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Expression and In Vivo Characterization of the Antimicrobial Peptide Oncocin and Variants Binding to Ribosomes
Published in Biochemistry (Easton) (15-09-2020)“…Peptides have important biomedical applications, but poor correlation between in vitro and in vivo activities can limit their development for clinical use. The…”
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Phase‐separated bacterial ribonucleoprotein bodies organize mRNA decay
Published in Wiley interdisciplinary reviews. RNA (01-11-2020)“…In bacteria, mRNA decay is controlled by megadalton scale macromolecular assemblies called, “RNA degradosomes,” composed of nucleases and other RNA decay…”
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Cover Image
Published in Wiley interdisciplinary reviews. RNA (01-11-2020)“…The cover image is based on the Advanced Review Phase‐separated bacterial ribonucleoprotein bodies organize mRNA decay by Nisansala S. Muthunayake et al.,…”
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New Processes for Ionizing Nonvolatile Compounds in Mass Spectrometry: The Road of Discovery to Current State-of-the-Art
Published in Journal of the American Society for Mass Spectrometry (07-10-2024)“…This covers discovery and mechanistic aspects as well as initial applications of novel ionization processes for use in mass spectrometry that guided us in a…”
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