Search Results - "Muthu Kumaradoss, Kathiravan"

Discovery and development of COVID‐19 vaccine from laboratory to clinic by Saravanan, Venkatesan, Chagaleti, Bharath Kumar, Narayanan, Pavithra Lakshmi, Anandan, Vijay Babu, Manoharan, Haritha, Anjana, G.V., Peraman, Ramalingam, Namasivayam, S. Karthik Raja, Kavisri, M., Arockiaraj, Jesu, Muthu Kumaradoss, Kathiravan, Moovendhan, Meivelu

“…The world has recently experienced one of the biggest and most severe public health disasters with severe acute respiratory syndrome coronavirus (SARS‐CoV‐2)…”
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Exploring Pyrimidine Pharmacophore as Thymidine Monophosphate Kinase Inhibitors for Antitubercular Activity: A Review by Chitre, Trupti Sameer, Asgaonkar, Kalyani Dhirendra, Patil, Shital Manoj, Kathiravan, Muthu Kumaradoss, Padhye, Subhash Balkrishna

“…Tuberculosis (TB) has been declared as a health emergency due to emergence of resistant strains of M. tuberculosis, multidrug resistant (MDR), extensively drug…”
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Strategies in the Design and Development of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) by Vanangamudi, Murugesan, Palaniappan, Senthilkumar, Kathiravan, Muthu Kumaradoss, Namasivayam, Vigneshwaran

“…AIDS (acquired immunodeficiency syndrome) is a potentially life-threatening infectious disease caused by human immunodeficiency virus (HIV). To date, thousands…”
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COX-2 targeted therapy for diabetic foot ulcers using T7-enhanced CS-PVA membranes by Murugan, Raghul, Ashok, Kumar, Ramya Ranjan Nayak, S.P., Deivasigamani, Priya, Almutairi, Mikhlid H., Almutairi, Bader O., Guru, Ajay, Muthu Kumaradoss, Kathiravan, Arockiaraj, Jesu

“…•Chitosan-polyvinylalcohol (CS-PVA) membrane inhibits growth of pathogenic bacteria.•T7, a selective COX-2 inhibitor accelerates wound healing potential of…”
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A novel brominated chalcone derivative as a promising multi-target inhibitor against multidrug-resistant Listeria monocytogenes by Haridevamuthu, B., Nayak, S.P. Ramya Ranjan, Madesh, S., Dhivya, L.S., Chagaleti, Bharath Kumar, Pasupuleti, Mukesh, Rajakrishnan, R., Alfarhan, Ahmed, Muthu Kumaradoss, Kathiravan, Arockiaraj, Jesu

“…Foodborne pathogens continue to challenge public health due to their ability to cause severe illness and their increasing resistance to current antimicrobial…”
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Targeting cyclin-dependent kinase 2 CDK2: Insights from molecular docking and dynamics simulation – A systematic computational approach to discover novel cancer therapeutics by Chagaleti, Bharath Kumar, B., Shantha Kumar, G.V., Anjana, Rajagopal, Rajakrishnan, Alfarhan, Ahmed, Arockiaraj, Jesu, Muthu Kumaradoss, Kathiravan, Karthick Raja Namasivayam, S.

“…Global public health is confronted with significant challenges due to the prevalence of cancer and the emergence of treatment resistance. This work focuses on…”
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Furan-based Chalcone Annihilates the Multi-Drug-Resistant Pseudomonas aeruginosa and Protects Zebra Fish Against its Infection by Nayak, Santosh Pushpa Ramya Ranjan, Basty, Catharine, Boopathi, Seenivasan, Dhivya, Loganathan Sumathi, Alarjani, Khaloud Mohammed, Gawwad, Mohamed Ragab Abdel, Hager, Raghda, Kathiravan, Muthu Kumaradoss, Arockiaraj, Jesu

“…The emergence of carbapenem-resistant Pseudomonas aeruginosa , a multi-drug-resistant bacteria, is becoming a serious public health concern. This bacterium…”
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An Overview of Spike Surface Glycoprotein in Severe Acute Respiratory Syndrome-Coronavirus by Kathiravan, Muthu Kumaradoss, Radhakrishnan, Srimathi, Namasivayam, Vigneshwaran, Palaniappan, Senthilkumar

“…The novel coronavirus originated in December 2019 in Hubei, China. This contagious disease named as COVID-19 resulted in a massive expansion within 6 months by…”
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Dual Anti-Inflammatory and Anticancer Activity of Novel 1,5-Diaryl Pyrazole Derivatives: Molecular Modeling, Synthesis, In Vitro Activity, and Dynamics Study by Deivasigamani, Priya, Rubavathy, S M Esther, Jayasankar, Narayanan, Saravanan, Venkatesan, Thilagavathi, Ramasamy, Prakash, Muthuramalingam, Selvam, Chelliah, Rajagopal, Rajakrishnan, Alfarhan, Ahmed, Kathiravan, Muthu Kumaradoss, Arokiyaraj, Selvaraj, Arockiaraj, Jesu

“…A series of novel 1,5-diaryl pyrazole derivatives targeting the COX enzyme were designed by combined ligand and structure-based approach. The designed…”
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Synthesis of Novel Furan-Based Chalcone Derivatives As Anti-Tuberculosis Agents: In Vitro , Cytotoxicity Assessment and In Silico by Dhivya, Loganathan Sumathi, Kumaradoss, Kathiravan Muthu

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Protective effect of a novel furan hybrid chalcone against bisphenol A-induced craniofacial developmental toxicity in zebrafish embryos by Haridevamuthu, B., Madesh, S., Bharti, Ankit Kumar, Dhivya, L.S., Rajagopal, Rajakrishnan, Alfarhan, Ahmed, Kathiravan, Muthu Kumaradoss, Arockiaraj, Jesu

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1,5- diaryl pyrazole-loaded chitosan nanoparticles as COX-2 inhibitors, mitigate neoplastic growth by regulating NF-κB pathway in-vivo zebrafish model by Murugan, Raghul, Selvam, Madesh, Haridevamuthu, B., Ashok, Kumar, Chagaleti, Bharath Kumar, Priya, D., Rajagopal, Rajakrishnan, Alfarhan, Ahmed, Kumaradoss, Kathiravan Muthu, Arockiaraj, Jesu

“…Non-steroidal anti-inflammatory drugs (NSAIDs) have been researched for their capacity to reduce cancer incidence, primarily due to their COX-2 inhibition…”
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Protective role of 2-aminothiazole derivative against ethanol-induced teratogenic effects in-vivo zebrafish by Madesh, S., Sudhakaran, Gokul, Ramamurthy, Karthikeyan, Sau, Avra, Muthu Kumaradoss, Kathiravan, Almutairi, Mikhlid H., Almutairi, Bader O., Palaniappan, Senthilkumar, Arockiaraj, Jesu

“…[Display omitted] Teratology investigates the origins of congenital disabilities, often linked to environmental factors such as ethanol (EtOH) exposure…”
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Daidzein ameliorates nonmotor symptoms of manganese‐induced Parkinsonism in zebrafish model: Behavioural and biochemical approach by Haridevamuthu, Balasubramanian, Sudhakaran, Gokul, Pachaiappan, Raman, Kathiravan, Muthu Kumaradoss, Manikandan, Krishnan, Almutairi, Mikhlid H., Almutairi, Bader O., Arokiyaraj, Selvaraj, Arockiaraj, Jesu

“…Background and Purpose Parkinson's disease (PD) is a prevalent neurodegenerative movement disorder characterized by motor dysfunction. Environmental factors,…”
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Multifaceted evaluation of pyrazole derivative (T4)-chitosan (CS) nanoparticles: Morphology, drug release, and anti-tumor efficacy in a rat model by Murugan, Raghul, Nayak, S.P. Ramya Ranjan, Haridevamuthu, B., Priya, D., Rajagopal, Rajakrishnan, Pasupulieti, Mukesh, Guru, Ajay, Kumaradoss, Kathiravan Muthu, Arockiaraj, Jesu

“…The development of targeted nanotherapeutics has emerged as a pivotal advancement in cancer treatment, aiming to enhance the efficacy and specificity of drug…”
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Toxicity and therapeutic property of dioxopiperidin derivative SKT40 demonstrated in-vivo zebrafish model due to inflammatory bowel disease by Aswinanand, B., Nayak, S.P. Ramya Ranjan, Madesh, S., Subbarayudu, Suthi, Kaliraj, S., Rajagopal, Rajakrishnan, Alfarhan, Ahmed, Kathiravan, Muthu Kumaradoss, Arockiaraj, Jesu

“…Inflammatory bowel disease (IBD) encompasses chronic disorders that cause severe inflammation in the digestive tract. This study evaluates…”
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Investigating the osteoprotective effects of quercetin and rutin from Terminalia chebula in glucocorticoid-induced osteoporosis in vitro cell line and in vivo zebrafish model by Priya, P. Snega, Nayak, S. P. Ramya Ranjan, Margesan, Thirumal, Chitra, Vellapandian, Almutairi, Mikhlid H., Almutairi, Bader O., Kumaradoss, Kathiravan Muthu, Namasivayam, S. Karthick Raja, Arockiaraj, Jesu

“…Terminalia chebula, called as king of traditional Tibetan medicine, contains bioactive compounds such as quercetin and rutin, which have been implicated in…”
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Combined effects of vitamin D3 and dioxopiperidinamide derivative on lipid homeostasis, inflammatory pathways, and redox imbalance in non-alcoholic fatty liver disease in vivo zebrafish model by Dharshan, Santhanam Sanjai, Ramamurthy, Karthikeyan, Kaliraj, Salamuthu, Manikandan, Krishnan, Chitra, Vellapandian, Rajagopal, Rajakrishnan, Alfarhan, Ahmed, Namasivayam, S Karthick Raja, Kathiravan, Muthu Kumaradoss, Arockiaraj, Jesu

“…Liver damage and metabolic dysfunctions, the defining features of non-alcoholic fatty liver disease (NAFLD), are marked by inflammation, oxidative stress, and…”
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Identification of novel CA IX inhibitor: Pharmacophore modeling, docking, DFT, and dynamic simulation by Packiapalavesam, Shakthi Devi, Saravanan, Venkatesan, Mahajan, Anand A., Almutairi, Mikhlid H., Almutairi, Bader O., Arockiaraj, Jesu, Kathiravan, Muthu Kumaradoss, Karthick Raja Namasivayam, S.

“…Human Carbonic anhydrase IX (hCA IX) is found to be an essential biomarker for the treatment of hypoxic tumors in both the early and metastatic stages of…”
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