Search Results - "Muth, E A"

2-Phenyl-2-(1-hydroxycycloalkyl)ethylamine derivatives: synthesis and antidepressant activity by Yardley, John P, Husbands, G. E. Morris, Stack, Gary, Butch, Jacqueline, Bicksler, James, Moyer, John A, Muth, Eric A, Andree, Terrance, Fletcher, Horace

“…A series of 2-phenyl-2-(1-hydroxycycloalkyl)ethylamine derivatives was examined for the ability to inhibit both rat brain imipramine receptor binding and the…”
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Antidepressant biochemical profile of the novel bicyclic compound Wy-45,030, an ethyl cyclohexanol derivative by Muth, E A, Haskins, J T, Moyer, J A, Husbands, G E, Nielsen, S T, Sigg, E B

“…The novel bicyclic compound Wy-45,030 [1-2-(dimethylamino)-1-(4-methoxyphenyl)ethyl cyclohexanol, hydrochloride] exhibited a neurochemical profile predictive…”
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Regional distribution of calmodulin activity in rat brain by Zhou, L W, Moyer, J A, Muth, E A, Clark, B, Palkovits, M, Weiss, B

“…Calmodulin activity in 68 discrete areas of rat brain, obtained by micropunch technique, was assessed by its capacity to activate a calmodulin-sensitive form…”
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Antipsychotic activity of substituted .gamma.-carbolines by Abou-Gharbia, Magid, Patel, Usha R, Webb, Michael B, Moyer, John A, Andree, Terrance H, Muth, Eric A

“…Several novel substituted gamma-carbolines were synthesized and examined in a series of in vitro and in vivo pharmacological tests to determine potential…”
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DMI, Wy-45,030, Wy-45,881 and ciramadol inhibit locus coeruleus neuronal activity by Haskins, J T, Moyer, J A, Muth, E A, Sigg, E B

“…Wy-45,030 and Wy-45,881 block the uptake of norepinephrine and serotonin in rat brain synaptosomal preparations and share several in vivo and in vitro effects…”
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Biochemical and electrophysiological studies of the psychotropic compound, amperozide by Haskins, J T, Muth, E A, Andree, T H

“…Amperozide (AB Ferrosan, FG 5606), a new antiaggressive agent which exhibits a diverse preclinical profile of in vivo and in vitro activities, was examined to…”
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Psychotropic agents: synthesis and antipsychotic activity of substituted .beta.-carbolines by Abou-Gharbia, Magid, Patel, Usha R, Moyer, John A, Muth, Eric A

“…A series of novel substituted beta-carbolines was synthesized and tested for potential antipsychotic activity. Several compounds displayed moderate…”
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Polycyclic aryl- and heteroarylpiperazinyl imides as 5-HT1A receptor ligands and potential anxiolytic agents: synthesis and structure-activity relationship studies by Abou-Gharbia, Magid, Patel, Usha R, Webb, Michael B, Moyer, John A, Andree, Terrance H, Muth, Eric A

“…A series of polycyclic aryl- and heteroarylpiperazinyl imides were prepared and tested in various receptor-binding and behavioral tests. Parameters measured…”
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Changes in central cholinergic neurons in the spontaneously hypertensive rat by Helke, C J, Muth, E A, Jacobowitz, D M

“…The activity of choline acetyltransferase (ChAT) was measured in discrete areas of the brain in 4-, 8- and 12-week-old spontaneously hypertensive rats (SH…”
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Stria medullaris: a possible pathway containing GABAergic afferents to the lateral habenula by Gottesfeld, Z, Massari, V J, Muth, E A, Jacobowitz, D M

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Venlafaxine: a new dimension in antidepressant pharmacotherapy

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Lack of biochemical evidence for a direct habenulo-raphe GABAergic pathway by Gottesfeld, Z, Hoover, D B, Muth, E A, Jacobowitz, D M

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Effect of gonadal hormones on luteinizing hormone in plasma and on choline acetyltransferase activity and acetylcholine levels in discrete nuclei of the rat brain by Muth, E A, Crowley, W R, Jacobowitz, D M

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Biochemical mapping of noradrenergic projections of axons in the dorsal noradrenergic bundle by Roizen, M F, Kobayashi, R M, Muth, E A, Jacobowitz, D M

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Evidence that noradrenaline modulates the increase in striatal dopamine metabolism induced by muscarinic receptor stimulation by Weinstock, M, Zavadil, 3rd, A P, Muth, E A, Crowley, W R, O'Donohue, T L, Jacobowitz, D M, Kopin, I J

“…The effect of oxotremorine was studied on the concentration of homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylethylglycol (MHPG) in the corpus striatum…”
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A method for the discrete removal of a segment of the dorsal noradrenergic bundle and its application to analysis of catecholamine and dopamine-beta-hydroxylase by Jacobowitz, D M, Roizen, M F, Suttora, N L, Muth, E A

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Polycyclic aryl- and heteroarylpiperazinyl imides as 5-HT sub(1A) receptor ligands and potential anxiolytic agents: Synthesis and structure-activity relationship studies by Abou-Gharbia, M, Patel, U R, Webb, M B, Moyer, JA, Andree, TH, Muth, E A

“…A series of polycyclic aryl- and heteroarylpiperazinyl imides were prepared and tested in various receptor-binding and behavioral tests. Parameters measured…”
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A mapping of the distribution of acetycholine, choline acetyltransferase and acetylcholinesterase in discrete areas of rat brain by Hoover, D B, Muth, E A, Jacobowitz, D M

“…Acetylcholine (ACh) concentration, choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) were measured in 60 discrete areas dissected from the rat…”
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Effects of ovarian hormones on levels of luteinizing hormone in plasma and on serotonin concentrations in discrete brain nuclei by Crowley, W R, O'Donohue, T L, Muth, E A, Jacobowitz, D M

“…Levels of serotonin were measureed in microdissected, individual brain nuclei in ovariectomized rats after treatment with ovarian hormones. Regions sampled…”
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The effect of two anesthetic agents on norepinephrine and dopamine in discrete brain nuclei, fiber tracts, and terminal regions of the rat by Roizen, M F, Kopin, I J, Zivin, J, Muth, E A, Jacobowitz, D M

“…Catecholaminergic neurons have been implicated in the mechanism of general anesthesia, but previous attempts at measuring changes in adrenergic neuron function…”
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