Search Results - "Mutak, Stjepan"

Azalides from Azithromycin to New Azalide Derivatives by Mutak, Stjepan

“…Azalides are semi-synthetic macrolides, in which a nitrogen atom is introduced into a macrolactone ring via a Beckmann rearrangement. Starting from…”
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Od vitamina do antibiotika – sjećanja jednog kemičara II. dio by Mutak, Stjepan

“…U drugom je dijelu Sjećanja autor na mnogim primjerima prikazao kako se kombinacijom stečenog znanja i iskustva može efikasnije unaprijediti kemijska reakcija,…”
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Od vitamina do antibiotika – sjećanja jednog kemičara I. dio by Mutak, Stjepan

“…Opisan je radni vijek i usavršavanje jednog organsko-sintetskog kemičara s Tehnološkog fakulteta (sada Fakulteta kemijskog inženjerstva i tehnologije) u…”
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Initial Scale-Up and Process Improvements for the Preparation of a Lead Antibacterial Macrolone Compound by Štimac, Vlado, Matanović Škugor, Maja, Palej Jakopović, Ivana, Vinter, Adrijana, Ilijaš, Marina, Alihodžić, Sulejman, Mutak, Stjepan

“…Macrolones are a novel class of potent antimicrobial agents that consist of a macrolide scaffold to which a quinolone unit is tethered by various linkers to…”
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Synthesis and biological properties of 4″-O-acyl derivatives of 8a-Aza-8a-homoerythromycin by Stimac, Vlado, Alihodzic, Sulejman, Lazarevski, Gorjana, Mutak, Stjepan, Istuk, Zorica Marusic, Fajdetic, Andrea, Palej, Ivana, Paljetak, Hana Cipcic, Padovan, Jasna, Tavcar, Branka, Haber, Vesna Erakovic

“…A series of 4″- O- acyl derivatives of 8a-aza-8a-homoerythromycins A were synthesized and tested against Gram-positive and Gram-negative bacteria. Derivatives…”
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Synthesis and antibacterial evaluation of novel 4″-glycyl linked quinolyl-azithromycins with potent activity against macrolide-resistant pathogens by Pavlović, Dražen, Mutak, Stjepan

“…[Display omitted] A new azithromycin-based series of antibacterial macrolones is reported, which features the use of a 4″-ester linked glycin for tethering the…”
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Synthesis and Antibacterial Activity of Isomeric 15-Membered Azalides by Alihodzic, Sulejman, Fajdetic, Andrea, Kobrehel, Gabrijela, Lazarevski, Gorjana, Mutak, Stjepan, Pavlovic, Drazen, Stimac, Vlado, Cipcic, Hana, Kramaric, Miroslava Dominis, Erakovic, Vesna, Hasenöhrl, Andreja, Marsic, Natasa, Schoenfeld, Wolfgang

“…A series of 3-keto and 3-O-acyl derivatives of both 6-O-alkyl-8a-aza-8a-homoerythromycin A and 6-O-alkyl-9a-aza-9a-homo-erythromycin A were synthesised and…”
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Synthesis and antibacterial evaluation of novel 4 double prime -glycyl linked quinolyl-azithromycins with potent activity against macrolide-resistant pathogens by Pavlovic, Drazen, Mutak, Stjepan

“…A new azithromycin-based series of antibacterial macrolones is reported, which features the use of a 4 double prime -ester linked glycin for tethering the…”
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Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity by Pavlović, Dražen, Kimmins, Scott, Mutak, Stjepan

“…A novel series of 6-O-substituted 8a-aza-8a-homoerythromycin A 3-O-acylides has been discovered with potent activity against key respiratory pathogens,…”
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New amidino-benzimidazolyl derivatives of tylosin and desmycosin by Hranjec, Marijana, Starcević, Kristina, Zamola, Branimir, Mutak, Stjepan, Derek, Marko, Karminski-Zamola, Grace

“…New amidino-benzimidazolyl derivatives of antibiotics tylosin and desmycosin are prepared in the reaction of corresponding amidino-substituted…”
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Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials by Pavlović, Dražen, Fajdetić, Andrea, Mutak, Stjepan

“…A series of novel 6-O-substituted and 6,12-di-O-substituted 8a-aza-8a-homoerythromycin A and 9a-aza-9a-homoerythromycin A ketolides were synthesized and…”
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Synthesis and Structure−Activity Relationships of Novel 8a-Aza-8a-homoerythromycin A Ketolides by Pavlović, Dražen, Mutak, Stjepan

“…A series of novel 6-O-substituted 8a-aza-8a-homoerythromycin A ketolides was synthesized and evaluated for in vitro antibacterial activity. Key strategic…”
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Discovery of 4′′-Ether Linked Azithromycin-Quinolone Hybrid Series: Influence of the Central Linker on the Antibacterial Activity by Pavlović, Dražen, Mutak, Stjepan

“…A series of novel C-4′′-substituted azithromycins was synthesized and evaluated for in vitro antibacterial activity against a panel of representative…”
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Synthesis and Structure–Activity Relationships of α‑Amino-γ-lactone Ketolides: A Novel Class of Macrolide Antibiotics by Pavlović, Dražen, Mutak, Stjepan, Andreotti, Daniele, Biondi, Stefano, Cardullo, Francesca, Paio, Alfredo, Piga, Elisa, Donati, Daniele, Lociuro, Sergio

“…An efficient synthesis of α-amino-γ-lactone ketolide (3) was developed, which provided a versatile intermediate for the incorporation of a variety of aryl and…”
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Synthesis and biological activity of 4″- O-acyl derivatives of 14- and 15-membered macrolides linked to ω-quinolone-carboxylic unit by Škugor, Maja Matanović, Štimac, Vlado, Palej, Ivana, Lugarić, Đurdjica, Paljetak, Hana Čipčić, Filić, Darko, Modrić, Marina, Đilović, Ivica, Gembarovski, Dubravka, Mutak, Stjepan, Eraković Haber, Vesna, Holmes, David J., Ivezić-Schoenfeld, Zrinka, Alihodžić, Sulejman

“…The synthesis and antimicrobial activity of a new class of macrolide antibiotics which consist of a macrolide scaffold and a quinolone unit covalently…”
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Synthesis, activity and pharmacokinetics of novel antibacterial 15-membered ring macrolones by Fajdetić, Andrea, Vinter, Adrijana, Paljetak, Hana Čipčić, Padovan, Jasna, Jakopović, Ivana Palej, Kapić, Samra, Alihodžić, Sulejman, Filić, Darko, Modrić, Marina, Košutić-Hulita, Nada, Antolović, Roberto, Schoenfeld, Zrinka Ivezić, Mutak, Stjepan, Haber, Vesna Eraković, Spaventi, Radan

“…Synthesis, antibacterial activity and pharmacokinetic properties of a novel class of macrolide antibiotics—macrolones—derived from azithromycin, comprising…”
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Novel 8a-aza-8a-homoerythromycin—4″-(3-substituted-amino)propionates with broad spectrum antibacterial activity by Hutinec, Antun, Đerek, Marko, Lazarevski, Gorjana, Šunjić, Vitomir, Paljetak, Hana Čipčić, Alihodžić, Sulejman, Haber, Vesna Eraković, Dumić, Miljenko, Maršić, Nataša, Mutak, Stjepan

“…Fifteen-membered 8a-aza-8a-homoerythromycins derived from either erythromycin or clarithromycin have been acylated to form 4″-O-propenoyl derivative. These…”
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Novel 9a-carbamoyl- and 9a-thiocarbamoyl-3-decladinosyl-6-hydroxy and 6-methoxy derivatives of 15-membered macrolides by Ištuk, Zorica Marušić, Mutak, Stjepan, Kujundžić, Nedjeljko, Kragol, Goran

“…An efficient method for the synthesis of diverse 9a-carbamoyl- and 9a-thiocarbamoyl-3-decladinosyl-6-hydroxy and 3-decladinosyl-6-methoxy derivatives of…”
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Novel 8a-aza-8a-homoerythromycin - 4QUOTATION_MARK-(3-substituted-amino)propionates with broad spectrum antibacterial activity by Hutinec, Antun, Derek, Marko, Lazarevski, Gorjana, Sunjic, Vitomir, Paljetak, Hana Cipcic, Alihodzic, Sulejman, Haber, Vesna Erakovic, Dumic, Miljenko, Marsic, Natasa, Mutak, Stjepan

“…Fifteen-membered 8a-aza-8a-homoerythromycins derived from either erythromycin or clarithromycin have been acylated to form 4"-O-propenoyl derivative. These…”
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Synthesis and Structural Properties of Novel Tricyclic 15-membered Azalides by Fajdetic, Andrea, Kobrehel, Gabrijela, Lazarevski, Gorjana, Marusic-Istuk, Zorica, Mutak, Stjepan

“…Starting from 3-decladinosyl-9a, 11-cyclic carbamates of 15 membered azalide, strained tricyclic aglycone derivatives were prepared. The bridging 5-membered…”
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