Search Results - "Mustonen, Jukka"
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Uncovering the mysteries of hantavirus infections
Published in Nature reviews. Microbiology (01-08-2013)“…Key Points Hantaviruses are negative-sense single-stranded RNA viruses that infect many species of rodents, shrews, moles and bats. Hantaviruses primarily…”
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Hantavirus Research in Finland: Highlights and Perspectives
Published in Viruses (26-07-2021)“…Finland has the highest incidence of hantavirus infections globally, with a significant impact on public health. The large coverage of boreal forests and the…”
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Neutrophil Activation in Acute Hemorrhagic Fever With Renal Syndrome Is Mediated by Hantavirus-Infected Microvascular Endothelial Cells
Published in Frontiers in immunology (18-09-2018)“…Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) in humans. Both diseases are considered to be…”
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Differences in heart rate responses to upright posture are associated with variations in the high-frequency power of heart rate variability
Published in American journal of physiology. Heart and circulatory physiology (01-03-2024)“…High resting heart rate is a cardiovascular risk factor, but limited data exist on the underlying hemodynamics and reproducibility of supine-to-upright…”
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High plasma resistin associates with severe acute kidney injury in Puumala hantavirus infection
Published in PloS one (05-12-2018)“…Puumala hantavirus (PUUV) infected patients typically suffer from acute kidney injury (AKI). Adipokines have inflammation modulating functions in acute…”
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Individual changes of central blood pressure in response to upright posture: different hemodynamic phenotypes
Published in Journal of hypertension (01-12-2021)“…Most studies about upright regulation of blood pressure have focused on orthostatic hypotension despite the diverse hemodynamic changes induced by orthostatic…”
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Long-Term Consequences of Puumala Hantavirus Infection
Published in Viruses (14-03-2022)“…Several viral infections are associated with acute and long-term complications. During the past two years, there have been many reports on post-infectious…”
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Hantavirus Research in Finland
Published in Viruses (10-10-2024)“…The articles in this Special Issue, "Hantavirus Research in Finland", were published between 2021 and 2022 [...]…”
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Circulating mucosal-like IgA responses increase with severity of Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome
Published in Frontiers in immunology (24-10-2024)“…Old World Orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS) characterized by increased vascular permeability and acute kidney injury (AKI)…”
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10
Angiotensin-Receptor Blockade versus Converting–Enzyme Inhibition in Type 2 Diabetes and Nephropathy
Published in The New England journal of medicine (04-11-2004)“…Both angiotensin II–receptor blockers and angiotensin-converting–enzyme (ACE) inhibitors are renoprotective, but direct, long-term comparisons of their use in…”
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Maturing neutrophils of lower density associate with thrombocytopenia in Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome
Published in Frontiers in immunology (01-07-2024)“…Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome (PUUV-HFRS) is characterized by strong neutrophil activation. Neutrophils are the most…”
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Hantavirus infection-induced B cell activation elevates free light chains levels in circulation
Published in PLoS pathogens (11-08-2021)“…In humans, orthohantaviruses can cause hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). An earlier study reported that…”
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Severity Biomarkers in Puumala Hantavirus Infection
Published in Viruses (28-12-2021)“…Annually, over 10,000 cases of hemorrhagic fever with renal syndrome (HFRS) are diagnosed in Europe. Puumala hantavirus (PUUV) causes most of the European HFRS…”
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Haemodynamics of hyperthyroidism: increased cardiac work and findings related to vasodilatation
Published in European thyroid journal (01-10-2024)“…Hyperthyroidism increases cardiovascular morbidity and mortality, but the underlying mechanisms are not fully understood. In this study we compared…”
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The pathogenesis of nephropathia epidemica: New knowledge and unanswered questions
Published in Antiviral research (01-12-2013)“…•Nephropathia epidemica is characterized by capillary leakage, coagulation defects and acute kidney failure.•Several biomarkers of NE disease severity have…”
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Innate lymphoid cells are activated in HFRS, and their function can be modulated by hantavirus-induced type I interferons
Published in PLoS pathogens (01-07-2024)“…Hantaviruses cause the acute zoonotic diseases hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Infected patients show…”
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Alcohol Consumption and Its Influence on the Clinical Picture of Puumala Hantavirus Infection
Published in Viruses (28-02-2022)“…Puumala hantavirus (PUUV) causes hemorrhagic fever with renal syndrome. Characteristic clinical findings include acute kidney injury (AKI), thrombocytopenia,…”
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Urine sodium excretion is related to extracellular water volume but not to blood pressure in 510 normotensive and never-treated hypertensive subjects
Published in Blood pressure (31-12-2023)“…We evaluated sodium intake in 510 subjects by measuring their 24-h sodium excretion to the urine and examined whether sodium intake was related with…”
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Monocyte subset redistribution from blood to kidneys in patients with Puumala virus caused hemorrhagic fever with renal syndrome
Published in PLoS pathogens (01-03-2021)“…Innate immune cells like monocytes patrol the vasculature and mucosal surfaces, recognize pathogens, rapidly redistribute to affected tissues and cause…”
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Atherogenic index of plasma is related to arterial stiffness but not to blood pressure in normotensive and never-treated hypertensive subjects
Published in Blood pressure (04-05-2019)“…Atherogenic index of plasma (AIP), defined as the logarithm of triglycerides to high-density lipoprotein cholesterol (HDL-C) ratio, is a strong predictor of…”
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