Search Results - "Musters, Anne"

Room for improvement in clinical trials for rare diseases by Musters, Anne, Tas, Sander W.

“…Trials studying rare diseases, including immune-mediated inflammatory diseases such as Castleman disease, hyper IgD syndrome and undifferentiated vasculitis,…”
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In Rheumatoid Arthritis, Synovitis at Different Inflammatory Sites Is Dominated by Shared but Patient-Specific T Cell Clones by Musters, Anne, Klarenbeek, Paul L, Doorenspleet, Marieke E, Balzaretti, Giulia, Esveldt, Rebecca E E, van Schaik, Barbera D C, Jongejan, Aldo, Tas, Sander W, van Kampen, Antoine H C, Baas, Frank, de Vries, Niek

“…Genetic and immunological evidence clearly points to a role for T cells in the pathogenesis of rheumatoid arthritis (RA). Selective targeting of such…”
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Sensitive B-cell receptor repertoire analysis shows repopulation correlates with clinical response to rituximab in rheumatoid arthritis by Pollastro, Sabrina, Musters, Anne, Balzaretti, Giulia, Niewold, Ilse, van Schaik, Barbera, Hässler, Signe, Verhoef, Catharina M, Pallardy, Marc, van Kampen, Antoine, Mariette, Xavier, de Vries, Niek

“…Although B-cell depleting therapy in rheumatoid arthritis (RA) is clearly effective, response is variable and does not correlate with B cell depletion itself…”
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In rheumatoid arthritis inflamed joints share dominant patient-specific B-cell clones by Musters, Anne, Balzaretti, Giulia, van Schaik, Barbera D. C., Jongejan, Aldo, van der Weele, Linda, Tas, Sander W., van Kampen, Antoine H. C., de Vries, Niek

“…Background In patients with rheumatoid arthritis (RA) different joints were shown to share the same dominant T-cell clones, suggesting shared characteristics…”
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Systematic evaluation of B-cell clonal family inference approaches by Balashova, Daria, van Schaik, Barbera D C, Stratigopoulou, Maria, Guikema, Jeroen E J, Caniels, Tom G, Claireaux, Mathieu, van Gils, Marit J, Musters, Anne, Anang, Dornatien C, de Vries, Niek, Greiff, Victor, van Kampen, Antoine H C

“…The reconstruction of clonal families (CFs) in B-cell receptor (BCR) repertoire analysis is a crucial step to understand the adaptive immune system and how it…”
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Iatrogenic caecal perforation two days after a caesarean section, a case report by Schweitzer, Donald, Musters, Anne-Claire, de Vries, Bart, Vijgen, Guy H.E.J.

“…and importance: The caesarean section is a widely spread procedure and 29.7 million times performed every year inn 169 countries in the world. Overall,…”
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Understanding repertoire sequencing data through a multiscale computational model of the germinal center by García-Valiente, Rodrigo, Merino Tejero, Elena, Stratigopoulou, Maria, Balashova, Daria, Jongejan, Aldo, Lashgari, Danial, Pélissier, Aurélien, Caniels, Tom G., Claireaux, Mathieu A. F., Musters, Anne, van Gils, Marit J., Rodríguez Martínez, María, de Vries, Niek, Meyer-Hermann, Michael, Guikema, Jeroen E. J., Hoefsloot, Huub, van Kampen, Antoine H. C.

“…Sequencing of B-cell and T-cell immune receptor repertoires helps us to understand the adaptive immune response, although it only provides information about…”
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Prevention of rheumatoid arthritis: A systematic literature review of preventive strategies in at-risk individuals by Frazzei, Giulia, Musters, Anne, de Vries, Niek, Tas, Sander W., van Vollenhoven, Ronald F.

“…Rheumatoid arthritis (RA) is an autoimmune disease characterized by symmetrical peripheral polyarthritis in the hands and/or feet, leading to long-term…”
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How to monitor safety and efficacy of biologic treatment in rare, therapy-refractory immune-mediated inflammatory diseases? by Musters, Anne, Tas, Sander W

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Incidence and risk factors for adalimumab and infliximab anti-drug antibodies in rheumatoid arthritis: A European retrospective multicohort analysis by Quistrebert, Jocelyn, Hässler, Signe, Bachelet, Delphine, Mbogning, Cyprien, Musters, Anne, Tak, Paul Peter, Wijbrandts, Carla Ann, Herenius, Marieke, Bergstra, Sytske Anne, Akdemir, Gülşah, Johannesson, Martina, Combe, Bernard, Fautrel, Bruno, Chollet-Martin, Sylvie, Gleizes, Aude, Donnellan, Naoimh, Deisenhammer, Florian, Davidson, Julie, Hincelin-Mery, Agnès, Dönnes, Pierre, Fogdell-Hahn, Anna, De Vries, Niek, Huizinga, Tom, Abugessaisa, Imad, Saevarsdottir, Saedis, Hacein-Bey-Abina, Salima, Pallardy, Marc, Broët, Philippe, Mariette, Xavier

“…To evaluate the incidence of anti-drug antibody (ADA) occurrences and ADA-related risk factors under adalimumab and infliximab treatment in rheumatoid…”
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Quantitative analysis of the CD4+ T cell response to therapeutic antibodies in healthy donors using a novel T cell:PBMC assay by Schultz, Heidi S, Reedtz-Runge, Stine Louise, Bäckström, B Thomas, Lamberth, Kasper, Pedersen, Christian R, Kvarnhammar, Anne M

“…Many biopharmaceuticals (BPs) are known to be immunogenic in the clinic, which can result in modified pharmacokinetics, reduced efficacy, allergic reactions…”
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Risk stratification integrating genetic data for factor VIII inhibitor development in patients with severe hemophilia A by Bachelet, Delphine, Albert, Thilo, Mbogning, Cyprien, Hässler, Signe, Zhang, Yuan, Schultze-Strasser, Stephan, Repessé, Yohann, Rayes, Julie, Pavlova, Anna, Pezeshkpoor, Behnaz, Liphardt, Kerstin, Davidson, Julie E, Hincelin-Méry, Agnès, Dönnes, Pierre, Lacroix-Desmazes, Sébastien, Königs, Christoph, Oldenburg, Johannes, Broët, Philippe

“…Replacement therapy in severe hemophilia A leads to factor VIII (FVIII) inhibitors in 30% of patients. Factor VIII gene (F8) mutation type, a family history of…”
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Discovery of Innovative Therapies for Rare Immune-Mediated Inflammatory Diseases via Off-Label Prescription of Biologics: The Case of IL-6 Receptor Blockade in Castleman's Disease by Musters, Anne, Assaf, Amira, Gerlag, Danielle M, Tak, Paul P, Tas, Sander W

“…Biologics have revolutionized the field of clinical immunology and proven to be both effective and safe in common immune-mediated inflammatory diseases (IMIDs)…”
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Anti-interleukin 6 receptor therapy for hyper-IgD syndrome by Musters, Anne, Tak, Paul Peter, Baeten, Dominique L P, Tas, Sander W

“…Hyper-IgD syndrome (HIDS) is a rare, severe hereditary autoinflammatory disease characterised by periodic fevers, elevated serum IgD levels and a wide range of…”
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Iatrogenic cecal perforation two days after a caesarian section by Schweitzer, Donald, Musters, Anne-Claire, Vijgen, Guy H E J

“…A 32-year-old healthy woman was seen two days after a complicated c-section with abdominal pain and vomiting. Inflammatory parameters were high and imaging…”
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Iatrogenic caecal perforation two days after a caesarean section, a case report by Schweitzer, Donald, Musters, Anne-Claire, de Vries, Bart, Vijgen, Guy H E J

“…INTRODUCTIONand importance: The caesarean section is a widely spread procedure and 29.7 million times performed every year inn 169 countries in the world…”
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Off-label use of biologics for rare immunological disorders by Musters, Anne, Assaf, Amira, Baeten, Dominique L P, Tas, Sander W

“…Patients with severe therapy-refractory immune-mediated inflammatory diseases (IMIDs) are increasingly treated with biologics. Since official practice…”
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