Search Results - "Mustafi, Sourajit M."

Effects of acute alcohol exposure and chronic alcohol use on neurite orientation dispersion and density imaging (NODDI) parameters by Yoder, Karmen K., Chumin, Evgeny J., Mustafi, Sourajit M., Kolleck, Kelly A., Halcomb, Meredith E., Hile, Karen L., Plawecki, Martin H., O’Connor, Sean J., Dzemidzic, Mario, Wu, Yu-Chien

“…Rationale Little is known about how acute and chronic alcohol exposure may alter the in vivo membrane properties of neurons. Objectives We employed neurite…”
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White matter alterations in early-stage Alzheimer's disease: A tract-specific study by Wen, Qiuting, Mustafi, Sourajit M., Li, Junjie, Risacher, Shannon L., Tallman, Eileen, Brown, Steven A., West, John D., Harezlak, Jaroslaw, Farlow, Martin R., Unverzagt, Frederick W., Gao, Sujuan, Apostolova, Liana G., Saykin, Andrew J., Wu, Yu-Chien

“…Diffusion magnetic resonance imaging may allow for microscopic characterization of white matter degeneration in early stages of Alzheimer's disease. Multishell…”
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Monitoring Visual Cortical Activities During Progressive Retinal Degeneration Using Functional Bioluminescence Imaging by Narcisse, Darryl, Mustafi, Sourajit M, Carlson, Michael, Kim, Sanghoon, Batabyal, Subrata, Wright, Weldon, Mohanty, Samarendra K

“…Mouse models of inherited retinal degenerative diseases such as retinitis pigmentosa are characterized by degeneration of photoreceptors, which hinders the…”
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Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52 by Mustafi, Sourajit M, LeMaster, David M, Hernández, Griselda

“…As co-chaperones of Hsp90 (heat-shock protein 90), FKBP51 (FK506-binding protein of 51 kDa) and FKBP52 (FK506-binding protein of 52 kDa) act as antagonists in…”
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Detecting white matter alterations in multiple sclerosis using advanced diffusion magnetic resonance imaging by Mustafi, Sourajit, Harezlak, Jaroslaw, Kodiweera, Chandana, Randolph, Jennifer, Ford, James, Wishart, Heather, Wu, Yu-Chien

“…Multiple sclerosis is a neurodegenerative and inflammatory disease, a hallmark of which is demyelinating lesions in the white matter. We hypothesized that…”
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The Association Between Persistent White-Matter Abnormalities and Repeat Injury After Sport-Related Concussion by Brett, Benjamin L, Wu, Yu-Chien, Mustafi, Sourajit M, Saykin, Andrew J, Koch, Kevin M, Nencka, Andrew S, Giza, Christopher C, Goldman, Joshua, Guskiewicz, Kevin M, Mihalik, Jason P, Duma, Stefan M, Broglio, Steven P, McAllister, Thomas W, McCrea, Michael A, Meier, Timothy B

“…A recent systematic review determined that the physiological effects of concussion may persist beyond clinical recovery. Preclinical models suggest that…”
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Hybrid Diffusion Imaging in Mild Traumatic Brain Injury by Wu, Yu-Chien, Mustafi, Sourajit M, Harezlak, Jaroslaw, Kodiweera, Chandana, Flashman, Laura A, McAllister, Thomas W

“…Mild traumatic brain injury (mTBI) is an important public health problem. Although conventional medical imaging techniques can detect moderate-to-severe…”
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Structural differences between apolipoprotein E3 and E4 as measured by 19F NMR by Garai, Kanchan, Mustafi, Sourajit M., Baban, Berevan, Frieden, Carl

“…The apolipoprotein E family contains three major isoforms (ApoE4, E3, and E2) that are directly involved with lipoprotein metabolism and cholesterol transport…”
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Longitudinal white-matter abnormalities in sports-related concussion: A diffusion MRI study by Wu, Yu-Chien, Harezlak, Jaroslaw, Elsaid, Nahla M. H., Lin, Zikai, Wen, Qiuting, Mustafi, Sourajit M., Riggen, Larry D., Koch, Kevin M., Nencka, Andrew S., Meier, Timothy B., Mayer, Andrew R., Wang, Yang, Giza, Christopher C., DiFiori, John P., Guskiewicz, Kevin M., Mihalik, Jason P., LaConte, Stephen M., Duma, Stefan M., Broglio, Steven P., Saykin, Andrew J., McCrea, Michael A., McAllister, Thomas W.

“…OBJECTIVETo study longitudinal recovery trajectories of white matter after sports-related concussion (SRC) by performing diffusion tensor imaging (DTI) on…”
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N-terminal Myristoylation Regulates Calcium-induced Conformational Changes in Neuronal Calcium Sensor-1 by Jeromin, Andreas, Muralidhar, Dasari, Parameswaran, Malavika Nair, Roder, John, Fairwell, Thomas, Scarlata, Suzanne, Dowal, Louisa, Mustafi, Sourajit M., Chary, Kandala V.R., Sharma, Yogendra

“…Neuronal calcium sensor-1 (NCS-1), a Ca2+-binding protein, plays an important role in the modulation of neurotransmitter release and phosphatidylinositol…”
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Effects of White-Matter Tract Length in Sport-Related Concussion: A Tractography Study from the NCAA-DoD CARE Consortium by Mustafi, Sourajit M, Yang, Ho-Ching, Harezlak, Jaroslaw, Meier, Timothy B, Brett, Benjamin L, Giza, Christopher C, Goldman, Joshua, Guskiewicz, Kevin M, Mihalik, Jason P, LaConte, Stephen M, Duma, Stefan M, Broglio, Steven P, McCrea, Michael A, McAllister, Thomas W, Wu, Yu-Chien

“…Sport-related concussion (SRC) is an important public health issue. White-matter alterations after SRC are widely studied by neuroimaging approaches, such as…”
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Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins by LeMaster, David M., Mustafi, Sourajit M., Brecher, Matthew, Zhang, Jing, Héroux, Annie, Li, Hongmin, Hernández, Griselda

“…Interchanging Leu-119 for Pro-119 at the tip of the β4-β5 loop in the first FK506 binding domain (FK1) of the FKBP51 and FKBP52 proteins, respectively, has…”
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Structural basis of conformational transitions in the active site and 80's loop in the FK506-binding protein FKBP12 by Mustafi, Sourajit M, Brecher, Matthew, Zhang, Jing, Li, Hongmin, Lemaster, David M, Hernández, Griselda

“…The extensive set of NMR doublings exhibited by the immunophilin FKBP12 (FK506-binding protein 12) arose from a slow transition to the cis-peptide…”
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Analysing the visible conformational substates of the FK506-binding protein FKBP12 by Mustafi, Sourajit M, Chen, Hui, Li, Hongmin, Lemaster, David M, Hernández, Griselda

“…The 1H-15N 2D NMR correlation spectrum of the widely studied FK506-binding protein FKBP12 (FK506-binding protein of 12 kDa) contains previously unreported peak…”
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Neurite orientation dispersion and density imaging can detect presymptomatic axonal degeneration in the spinal cord of ALS mice by Gatto, R G, Mustafi, S M, Amin, M Y, Mareci, T H, Wu, Yu-Chien, Magin, R L

“…Neurite orientation dispersion and density imaging (NODDI), a MRI multi-shell diffusion technique, has offered new insights for the study of microstructural…”
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Structural differences between apolipoprotein E3 and E4 as measured by (19)F NMR by Garai, Kanchan, Mustafi, Sourajit M, Baban, Berevan, Frieden, Carl

“…The apolipoprotein E family contains three major isoforms (ApoE4, E3, and E2) that are directly involved with lipoprotein metabolism and cholesterol transport…”
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Expression and purification of amyloid-β peptides from Escherichia coli by Garai, Kanchan, Crick, Scott L., Mustafi, Sourajit M., Frieden, Carl

“…Soluble oligomers and fibrillar deposits of amyloid beta (Aβ) are key agents of Alzheimer’s disease pathogenesis. However, the mechanism of amyloid aggregation…”
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Statistical allosteric coupling to the active site indole ring flip equilibria in the FK506-binding domain by Anderson, Janet S., Mustafi, Sourajit M., Hernández, Griselda, LeMaster, David M.

“…In solution, the Trp 59 indole ring at the base of the active site cleft in the FKBP domain protein FKBP12 is rotated by ~90° at a population level of 20%,…”
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Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6 by Chen, Hui, Mustafi, Sourajit M., LeMaster, David M., Li, Zhong, Héroux, Annie, Li, Hongmin, Hernández, Griselda

“…The primary known physiological function of FKBP12.6 involves its role in regulating the RyR2 isoform of ryanodine receptor Ca2+ channels in cardiac muscle,…”
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Substoichiometric inhibition of Aβ1–40 aggregation by a tandem Aβ40–1-Gly8-1-40 peptide by Mustafi, Sourajit M., Garai, Kanchan, Crick, Scott L., Baban, Berevan, Frieden, Carl

“…Aβ peptides aggregate to form insoluble and neurotoxic fibrils associated with Alzheimer's disease. Inhibition of the aggregation has been the subject of…”
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