Search Results - "Mustafa, Wan Mahadzir"

Genome wide profiling in oral squamous cell carcinoma identifies a four genetic marker signature of prognostic significance by Vincent-Chong, Vui King, Salahshourifar, Iman, Woo, Kar Mun, Anwar, Arif, Razali, Rozaimi, Gudimella, Ranganath, Rahman, Zainal Ariff Abdul, Ismail, Siti Mazlipah, Kallarakkal, Thomas George, Ramanathan, Anand, Wan Mustafa, Wan Mahadzir, Abraham, Mannil Thomas, Tay, Keng Kiong, Zain, Rosnah Binti

“…Cancers of the oral cavity are primarily oral squamous cell carcinomas (OSCCs). Many of the OSCCs present at late stages with an exceptionally poor prognosis…”
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Co-Expression of TWIST1 and ZEB2 in Oral Squamous Cell Carcinoma Is Associated with Poor Survival by Kong, Yink Heay, Syed Zanaruddin, Sharifah Nurain, Lau, Shin Hin, Ramanathan, Anand, Kallarakkal, Thomas George, Vincent-Chong, Vui King, Wan Mustafa, Wan Mahadzir, Abraham, Mannil Thomas, Abdul Rahman, Zainal Ariff, Zain, Rosnah Binti, Cheong, Sok Ching

“…Oral squamous cell carcinoma (OSCC) is an aggressive disease accounting for more than 260,000 cancer cases diagnosed and 128,000 deaths worldwide. A large…”
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Multi‐ethnic variations in the practice of oral cancer risk habits in a developing country by Ghani, Wan Maria Nabillah, Razak, Ishak Abdul, Doss, Jennifer Geraldine, Yang, Yi‐Hsin, Rahman, Zainal Ariff Abdul, Ismail, Siti Mazlipah, Abraham, Mannil Thomas, Wan Mustafa, Wan Mahadzir, Tay, Keng Kiong, Zain, Rosnah Binti

“…Objective To elucidate ethnic variations in the practice of oral cancer risk habits in a selected Malaysian population. Methods This retrospective case–control…”
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Valproic acid: Growth inhibition of head and neck cancer by induction of terminal differentiation and senescence by Gan, Chai Phei, Hamid, Sharifah, Hor, Seen Yii, Zain, Rosnah Binti, Ismail, Siti Mazlipah, Wan Mustafa, Wan Mahadzir, Teo, Soo Hwang, Saunders, Nicholas, Cheong, Sok Ching

“…Background There are limited studies on the effects of drugs that modulate epigenetic regulation for head and neck squamous cell carcinoma (HNSCC). This study…”
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Overexpression of MMP13 Is Associated with Clinical Outcomes and Poor Prognosis in Oral Squamous Cell Carcinoma by Rahman, Zainal Ariff Abdul, Ismail, Siti Mazlipah, Wan Mustafa, Wan Mahadzir, Abraham, Mannil Thomas, Tay, Keng Kiong, Cheong, Sok Ching, Zain, Rosnah Binti, Khor, Goot Heah, Yang, Yi-Hsin, Ramanathan, Anand, Kallarakkal, Thomas George, Siow, Ming Yhong, Karen-Ng, Lee Peng, Salahshourifar, Iman, Vincent-Chong, Vui King, Prepageran, Narayanan

“…Matrix metalloproteinase 13 (MMP13) plays a central role in the MMP activation cascade that enables degradation of the extracellular matrix and basement…”
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Survival of Oral Cancer Patients in Different Ethnicities by Ghani, Wan Maria Nabillah, Ramanathan, Anand, Prime, Stephen Stewart, Yang, Yi-Hsin, Razak, Ishak Abdul, Abdul Rahman, Zainal Ariff, Abraham, Mannil Thomas, Mustafa, Wan Mahadzir Wan, Tay, Keng Kiong, Kallarakkal, Thomas George, Doss, Jennifer Geraldine, Cheong, Sok Ching, Bustam, Anita Zarina, Zain, Rosnah Binti

“…Previous studies found that ethnicity influences oral cancer patients' survival; however, most studies were limited to certain ethnic groups particularly from…”
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Comparative sera proteomics analysis of differentially expressed proteins in oral squamous cell carcinoma by Wong, Yin-Ling, Ramanathan, Anand, Yuen, Kar Mun, Mustafa, Wan Mahadzir Wan, Abraham, Mannil Thomas, Tay, Keng Kiong, Rahman, Zainal Ariff Abdul, Chen, Yeng

“…Oral squamous cell carcinoma (OSCC) has increased in incidence from 1990 to 2017, especially in South and Southeast Asia. It is often diagnosed at an advanced…”
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Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin by Zanaruddin, Sharifah Nurain Syed, Yee, Pei San, Hor, Seen Yii, Kong, Yink Heay, Ghani, Wan Maria Nabillah Wan Abd, Mustafa, Wan Mahadzir Wan, Zain, Rosnah Binti, Prime, Stephen S, Rahman, Zainal Ariff Abd, Cheong, Sok-Ching

“…The frequency of common oncogenic mutations and TP53 was determined in Asian oral squamous cell carcinoma (OSCC). The OncoCarta(™) panel v1.0 assay was used to…”
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Genetic Alterations of Chromosome 8 Genes in Oral Cancer by Yong, Zachary Wei Ern, Zaini, Zuraiza Mohamad, Kallarakkal, Thomas George, Karen-Ng, Lee Peng, Rahman, Zainal Ariff Abdul, Ismail, Siti Mazlipah, Sharifah, Noor Akmal, Mustafa, Wan Mahadzir Wan, Abraham, Mannil Thomas, Tay, Keng Kiong, Zain, Rosnah Binti

“…The clinical relevance of DNA copy number alterations in chromosome 8 were investigated in oral cancers. The copy numbers of 30 selected genes in 33 OSCC…”
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Genome wide analysis of chromosomal alterations in oral squamous cell carcinomas revealed over expression of MGAM and ADAM9 by Vincent-Chong, Vui King, Anwar, Arif, Karen-Ng, Lee Peng, Cheong, Sok Ching, Yang, Yi-Hsin, Pradeep, Padmaja Jayaprasad, Rahman, Zainal Ariff Abdul, Ismail, Siti Mazlipah, Zaini, Zuraiza Mohamad, Prepageran, Narayanan, Kallarakkal, Thomas George, Ramanathan, Anand, Mohayadi, Nur Aaina Binti Mohd, Rosli, Nurul Shielawati Binti Mohamed, Mustafa, Wan Mahadzir Wan, Abraham, Mannil Thomas, Tay, Keng Kiong, Zain, Rosnah Binti

“…Despite the advances in diagnosis and treatment of oral squamous cell carcinoma (OSCC), mortality and morbidity rates have not improved over the past decade. A…”
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KRT13, FAIM2 and CYP2W1 mRNA Expression in Oral Squamous Cell Carcinoma Patients with Risk Habits by Hartanto, Firstine Kelsi, Karen-Ng, Lee Peng, Vincent-Chong, Vui King, Ismail, Siti Mazlipah, Mustafa, Wan Mahadzir Wan, Abraham, Mannil Thomas, Tay, Keng Kiong, Zain, Rosnah Binti

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Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies by Fadlullah, Muhammad Zaki Hidayatullah, Chiang, Ivy Kim-Ni, Dionne, Kalen R., Yee, Pei San, Gan, Chai Phei, Sam, Kin Kit, Tiong, Kai Hung, Ng, Adrian Kwok Wen, Martin, Daniel, Lim, Kue Peng, Kallarakkal, Thomas George, Mustafa, Wan Mahadzir Wan, Lau, Shin Hin, Abraham, Mannil Thomas, Zain, Rosnah Binti, Rahman, Zainal Ariff Abdul, Molinolo, Alfredo, Patel, Vyomesh, Gutkind, J. Silvio, Tan, Aik Choon, Cheong, Sok Ching

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KRT13, FAIM2 and CYP2W1 mRNA Expression in Oral Squamous Cell Carcinoma Patients with Risk Habits by Hartanto, Firstine Kelsi, Karen-Ng, Lee Peng, Vincent-Chong, Vui King, Ismail, Siti Mazlipah, Mustafa, Wan Mahadzir Wan, Abraham, Mannil Thomas, Tay, Keng Kiong, Zain, Rosnah Binti

“…Background: Expression of KRT13, FAIM2 and CYP2W1 appears to be influenced by risk habits, thus exploring the associations of these genes in oral squamous cell…”
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Identification of potential glycoprotein biomarkers in oral squamous cell carcinoma using sweet strategies by Wong, Yin-Ling, Anand, Ramanathan, Yuen, Kar Mun, Mustafa, Wan Mahadzir Wan, Abraham, Mannil Thomas, Tay, Keng Kiong, Rahman, Zainal Ariff Abdul, Chen, Yeng

“…The prevalence of oral squamous cell carcinoma (OSCC) is high in South and Southeast Asia regions. Most OSCC patients are detected at advanced stages low…”
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MDM2 SNP309 does not confer an increased risk to oral squamous cell carcinoma but may modulate the age of disease onset by Hamid, Sharifah, Yang, Yi-Hsin, Peng, Karen Ng Lee, Ismail, Siti Mazlipah, Zain, Rosnah Binti, Lim, Kue Peng, Wan Mustafa, Wan Mahadzir, Abraham, Mannil Thomas, Teo, Soo-Hwang, Cheong, Sok Ching

“…Summary The MDM2 SNP309 has been associated with increased expression of the protein which could suppress p53 function, and has been shown to modulate risk to…”
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Conservative Neck Dissection in Oral Cancer Patients: a 5 Year Retrospective Study in Malaysia by Balasundram, Sathesh, Mustafa, Wan Mahadzir Wan, Ip, Jolene, Adnan, Tassha Hilda, Supramaniam, Premaa

“…Objective: The impact of ablative oral cancer surgery was studied, with particular reference to recurrence and nodal metastasis, to assess survival probability…”
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High Serum Level of Retinol and α-Tocopherol Affords Protection Against Oral Cancer in a Multiethnic Population by Athirajan, Vimmitra, Razak, Ishak Abdul, Thurairajah, Nalina, Ghani, Wan Maria Nabillah, Ching, Helen-Ng Lee, Yang, Yi-Hsin, Peng, Karen-Ng Lee, Rahman, Zainal Ariff Abdul, Mustafa, Wan Mahadzir Wan, Abraham, Mannil Thomas, Kiong, Tay Keng, Mun, Yuen Kar, Jalil, Norma, Zain, Rosnah Binti

“…Background: A comparative cross-sectional study involving oral cancer patients and healthy individuals was designed to investigate associations between…”
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Downregulation of CRNN gene and genomic instability at 1q21.3 in oral squamous cell carcinoma by Salahshourifar, Iman, Vincent-Chong, Vui King, Chang, Hong-Yun, Ser, Hooi Leng, Ramanathan, Anand, Kallarakkal, Thomas George, Rahman, Zainal Ariff Abdul, Ismail, Siti Mazlipah, Prepageran, Narayanan, Mustafa, Wan Mahadzir Wan, Abraham, Mannil Thomas, Tay, Keng Kiong, Zain, Rosnah Binti

“…Objectives This study includes the direct sequencing of cornulin (CRNN) gene to elucidate the possible mechanism of CRNN downregulation and explore the genetic…”
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Four-protein signature accurately predicts lymph node metastasis and survival in oral squamous cell carcinoma by Zanaruddin, Sharifah Nurain Syed, BSc, Saleh, Amyza, PhD, Yang, Yi-Hsin, PhD, Hamid, Sharifah, BSc, Mustafa, Wan Mahadzir Wan, FDSRCPS, Khairul Bariah, A.A.N., PhD, Zain, Rosnah Binti, MS, Lau, Shin Hin, FDSRCS, Cheong, Sok Ching, PhD

“…Summary The presence of lymph node (LN) metastasis significantly affects the survival of patients with oral squamous cell carcinoma (OSCC). Successful…”
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Significant association of high-risk human papillomavirus (HPV) but not of p53 polymorphisms with oral squamous cell carcinomas in Malaysia by Saini, Rajan, Tang, Thean-Hock, Zain, Rosnah Binti, Cheong, Sok Ching, Musa, Kamarul Imran, Saini, Deepti, Ismail, Abdul Rashid, Abraham, Mannil Thomas, Mustafa, Wan Mahadzir Wan, Santhanam, Jacinta

“…Purpose The purpose of this study was to evaluate the role of HPV and p53 polymorphisms in oral squamous cell carcinomas (OSCC) affecting Malaysian population…”
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