Search Results - "Mustafa, Shamimunisa B."
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Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis
Published in The Journal of clinical investigation (15-11-2022)“…Preterm birth is the leading cause of death in children under 5 years of age. Premature infants who receive life-saving oxygen therapy often develop…”
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2
Comparison of Preterm and Term Wharton's Jelly-Derived Mesenchymal Stem Cell Properties in Different Oxygen Tensions
Published in Cells, tissues, organs (01-01-2018)“…Mesenchymal stem cells (MSCs) have shown promise as therapeutic agents in treating morbidities associated with premature birth. MSCs derived from the human…”
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Oxygen and mechanical ventilation impede the functional properties of resident lung mesenchymal stromal cells
Published in PloS one (06-03-2020)“…Resident/endogenous mesenchymal stromal cells function to promote the normal development, growth, and repair of tissues. Following premature birth, the effects…”
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4
Development of a peripheral blood transcriptomic gene signature to predict bronchopulmonary dysplasia
Published in American journal of physiology. Lung cellular and molecular physiology (01-01-2023)“…Bronchopulmonary dysplasia (BPD) is the most common lung disease of extreme prematurity, yet mechanisms that associate with or identify neonates with increased…”
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5
Prophylactic Administration of Mesenchymal Stromal Cells Does Not Prevent Arrested Lung Development in Extremely Premature-Born Non-Human Primates
Published in Stem cells translational medicine (03-03-2023)“…Premature birth is a leading cause of childhood morbidity and mortality and often followed by an arrest of postnatal lung development called bronchopulmonary…”
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6
IL-1 promotes α-epithelial Sodium Channel (α-ENaC) expression in murine lung epithelial cells: involvement of NF-κB
Published in Journal of cell communication and signaling (01-09-2020)“…Intra-amniotic exposure to proinflammatory cytokines such as interleukin-1 (IL-1) correlates with a decreased incidence of respiratory distress syndrome (RDS)…”
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7
IgA modulates respiratory dysfunction as a sequela to pulmonary chlamydial infection as neonates
Published in Pathogens and disease (01-04-2016)“…Neonatal Chlamydia lung infections are associated with serious sequelae such as asthma and airway hyper-reactivity in children and adults. Our previous studies…”
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8
Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life
Published in Laboratory investigation (01-10-2011)“…Respiratory dysfunction in adults has been correlated with neonatal Chlamydia trachomatis pneumonia in several studies, but a causal association has not been…”
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9
Mechanical stretch induces lung α-epithelial Na+ channel expression
Published in Experimental lung research (01-10-2014)“…ABSTRACT During fetal development physiological stretching helps drive lung growth and maturation. At birth, the α-subunit of the alveolar epithelial sodium…”
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10
Protein kinase A and mitogen-activated protein kinase pathways mediate cAMP induction of α-Epithelial Na+ channels (α-ENaC)
Published in Journal of cellular physiology (01-04-2008)“…A major mechanism for Na+ transport across epithelia occurs through epithelial Na+ channels (ENaC). ENaC is a multimeric channel consisting of three subunits…”
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11
Induction of serum- and glucocorticoid-induced kinase-1 (SGK1) by cAMP regulates increases in α-ENaC
Published in Journal of cellular physiology (01-12-2008)“…α‐ENaC expression and activity is regulated by a variety of hormones including β‐adrenergic agonists via the second messenger cAMP. We evaluated the early…”
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12
Regulation of epithelial Na+ channel (ENaC) in the salivary cell line SMG-C6
Published in Experimental biology and medicine (Maywood, N.J.) (01-05-2009)“…Glucocorticoids and mineralocorticoids modulate Na+ transport via epithelial Na+ channels (ENaC). The rat submandibular epithelial cell line, SMG-C6, expresses…”
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13
Mechanical ventilation down-regulates surfactant protein a and keratinocyte growth factor expression in premature rabbits
Published in Pediatric research (01-09-2007)“…Surfactant-associated proteins (SP-A, SP-B, and SP-C) are critical for the endogenous function of surfactant. Keratinocyte growth factor (KGF) and vascular…”
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14
Cyclic stretch attenuates effects of hyperoxia on cell proliferation and viability in human alveolar epithelial cells
Published in American journal of physiology. Lung cellular and molecular physiology (01-08-2006)“…The treatment of severe lung disease often requires the use of high concentrations of oxygen coupled with the need for assisted ventilation, potentially…”
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15
Expression of Nitric-oxide Synthase in Rat Kupffer Cells Is Regulated by cAMP
Published in The Journal of biological chemistry (27-02-1998)“…Treatment of cultured rat Kupffer cells with lipopolysaccharide (LPS) resulted in a time-dependent increase in the expression of the inducible isoform of…”
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16
Postnatal glucocorticoids induce alpha-ENaC formation and regulate glucocorticoid receptors in the preterm rabbit lung
Published in American journal of physiology. Lung cellular and molecular physiology (01-01-2004)“…At birth, lung fluid clearance is coupled to Na+ transport through epithelial Na+ channels (ENaC) in the distal lung epithelium. We evaluated the effect of…”
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17
Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis
Published in The Journal of clinical investigation (01-11-2022)“…Preterm birth is the leading cause of death in children under 5 years of age. Premature infants who receive life-saving oxygen therapy often develop…”
Get full text
Journal Article -
18
Analysis of Inflammatory Modulation on Term and Preterm Neonatal Gastrointestinal Non‐Human Primate Explants
Published in The FASEB journal (01-04-2016)“…Abstract only BACKGROUND Dysregulation of inflammatory processes are associated with intestinal injury, necrotizing enterocolitis, and risk of perforation in…”
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19
Effects of calcium channel antagonists on LPS-induced hepatic iNOS expression
Published in The American journal of physiology (01-08-1999)“…The onset of liver injury is a pivotal event during endotoxemia. Lipopolysaccharide (LPS) activates the Kupffer cells (KC), the resident macrophages of the…”
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20
Suppression of lipopolysaccharide‐induced nitric oxide synthase expression by platelet‐activating factor receptor antagonists in the rat liver and cultured rat kupffer cells
Published in Hepatology (Baltimore, Md.) (01-11-1999)“…Excessive nitric oxide (NO) generated by hepatic cells in response to lipopolysaccharide (LPS) and inflammatory substances (e.g., platelet‐activating factor…”
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