Search Results - "Mustafa, Gulam"

Vitamin E loaded resveratrol nanoemulsion for brain targeting for the treatment of Parkinson's disease by reducing oxidative stress by Pangeni, Rudra, Sharma, Shrestha, Mustafa, Gulam, Ali, Javed, Baboota, Sanjula

“…Resveratrol, a potent natural antioxidant, possesses a wide range of pharmacological activities, but its oral bioavailability is very low due to its extensive…”
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Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition by Anwar, Saleha, Shamsi, Anas, Shahbaaz, Mohd, Queen, Aarfa, Khan, Parvez, Hasan, Gulam Mustafa, Islam, Asimul, Alajmi, Mohamed F., Hussain, Afzal, Ahmad, Faizan, Hassan, Md. Imtaiyaz

“…Microtubule affinity regulating kinase (MARK4) is a potential drug target for different types of cancer as it controls the early step of cell division. In this…”
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Therapeutic targeting of microtubule affinity‐regulating kinase 4 in cancer and neurodegenerative diseases by Alam, Manzar, Ahmed, Sarfraz, Abid, Mohammad, Hasan, Gulam Mustafa, Islam, Asimul, Hassan, Md. Imtaiyaz

“…Abstract Microtubule affinity‐regulating kinase 4 (MARK4) is a member of the Ser/Thr protein kinase family, phosphorylates the microtubule‐connected proteins…”
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Probing the Inhibition of Microtubule Affinity Regulating Kinase 4 by N-Substituted Acridones by Voura, Maria, Khan, Parvez, Thysiadis, Savvas, Katsamakas, Sotiris, Queen, Aarfa, Hasan, Gulam Mustafa, Ali, Sher, Sarli, Vasiliki, Hassan, Md. Imtaiyaz

“…Microtubule affinity regulating kinase 4 (MARK4) becomes a unique anti-cancer drug target as its overexpression is responsible for different types of cancers…”
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Elucidation of Dietary Polyphenolics as Potential Inhibitor of Microtubule Affinity Regulating Kinase 4: In silico and In vitro Studies by Khan, Parvez, Rahman, Shafikur, Queen, Aarfa, Manzoor, Saaliqa, Naz, Farha, Hasan, Gulam Mustafa, Luqman, Suaib, Kim, Jihoe, Islam, Asimul, Ahmad, Faizan, Hassan, Md. Imtaiyaz

“…Microtubule affinity regulating kinase 4 (MARK4) is a Ser/Thr kinase belonging to AMPK-like family, has recently become an important drug target against cancer…”
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B Cell Lymphoma 2: A Potential Therapeutic Target for Cancer Therapy by Alam, Manzar, Ali, Sabeeha, Mohammad, Taj, Hasan, Gulam Mustafa, Yadav, Dharmendra Kumar, Hassan, Md. Imtaiyaz

“…Defects in the apoptosis mechanism stimulate cancer cell growth and survival. B cell lymphoma 2 (Bcl-2) is an anti-apoptotic molecule that plays a central role…”
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Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6 by Yousuf, Mohd, Shamsi, Anas, Khan, Parvez, Shahbaaz, Mohd, AlAjmi, Mohamed F, Hussain, Afzal, Hassan, Gulam Mustafa, Islam, Asimul, Rizwanul Haque, Qazi Mohd, Hassan, Md Imtaiyaz

“…Cyclin-Dependent Kinase 6 (CDK6) plays an important role in cancer progression, and thus, it is considered as an attractive drug target in anticancer…”
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Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents by Arshad, Mohammed F., Alam, Aftab, Alshammari, Abdullah Ayed, Alhazza, Mohammed Bader, Alzimam, Ibrahim Mohammed, Alam, Md Anish, Mustafa, Gulam, Ansari, Md Salahuddin, Alotaibi, Abdulelah M., Alotaibi, Abdullah A., Kumar, Suresh, Asdaq, Syed Mohammed Basheeruddin, Imran, Mohd, Deb, Pran Kishore, Venugopala, Katharigatta N., Jomah, Shahamah

“…For many decades, the thiazole moiety has been an important heterocycle in the world of chemistry. The thiazole ring consists of sulfur and nitrogen in such a…”
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Current and Future Prospective of Injectable Hydrogels-Design Challenges and Limitations by Almawash, Saud, Osman, Shaaban K, Mustafa, Gulam, El Hamd, Mohamed A

“…Injectable hydrogels (IHs) are smart biomaterials and are the most widely investigated and versatile technologies, which can be either implanted or inserted…”
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Targeting Tau Hyperphosphorylation via Kinase Inhibition: Strategy to Address Alzheimer's Disease by Turab Naqvi, Ahmad Abu, Hasan, Gulam Mustafa, Hassan, Md Imtaiyaz

“…Microtubule-associated protein tau is involved in the tubulin binding leading to microtubule stabilization in neuronal cells which is essential for…”
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Pharmacological Features and Therapeutic Implications of Plumbagin in Cancer and Metabolic Disorders: A Narrative Review by Sharma, Bhoomika, Dhiman, Chitra, Hasan, Gulam Mustafa, Shamsi, Anas, Hassan, Md Imtiyaz

“…Plumbagin (PLB) is a naphthoquinone extracted from . In recent times, there has been a growing body of evidence suggesting the potential importance of…”
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3D Printing Technology as a Promising Tool to Design Nanomedicine-Based Solid Dosage Forms: Contemporary Research and Future Scope by Ahmad, Javed, Garg, Anuj, Mustafa, Gulam, Mohammed, Abdul Aleem, Ahmad, Mohammad Zaki

“…3D printing technology in medicine is gaining great attention from researchers since the FDA approved the first 3D-printed tablet (Spritam ) on the market…”
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MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer's Disease Therapy by Shamsi, Anas, Anwar, Saleha, Mohammad, Taj, Alajmi, Mohamed F, Hussain, Afzal, Rehman, Md Tabish, Hasan, Gulam Mustafa, Islam, Asimul, Hassan, Md Imtaiyaz

“…Microtubule affinity-regulating kinase (MARK4) plays a key role in Alzheimer's disease (AD) development as its overexpression is directly linked to increased…”
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Mechanistic insights into the pathogenesis of neurodegenerative diseases: towards the development of effective therapy by Nazam, Fauzia, Shaikh, Sibhghatulla, Nazam, Nazia, Alshahrani, Abdulaziz Saad, Hasan, Gulam Mustafa, Hassan, Md.Imtaiyaz

“…Neurodegeneration is a prevalent and one of the emerging reasons for morbidity, mortality, and cognitive impairment in aging. Dementia is one of such…”
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Aurora B kinase: a potential drug target for cancer therapy by Ahmed, Azaj, Shamsi, Anas, Mohammad, Taj, Hasan, Gulam Mustafa, Islam, Asimul, Hassan, Md. Imtaiyaz

“…Background Ensuring genetic integrity is essential during the cell cycle to avoid aneuploidy, one of the underlying causes of malignancies. Aurora kinases…”
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Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases by Azhar, Md Khabeer, Anwar, Saleha, Hasan, Gulam Mustafa, Shamsi, Anas, Islam, Asimul, Parvez, Suhel, Hassan, Md Imtaiyaz

“…Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of species with…”
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Investigating regulated signaling pathways in therapeutic targeting of non-small cell lung carcinoma by Alam, Manzar, Hasan, Gulam Mustafa, Eldin, Sayed M., Adnan, Mohd, Riaz, Muhammad Bilal, Islam, Asimul, Khan, Ilyas, Hassan, Md. Imtaiyaz

“…Non-small cell lung carcinoma (NSCLC) is the most common malignancy worldwide. The signaling cascades are stimulated via genetic modifications in upstream…”
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Identification of Phytoconstituents as Potent Inhibitors of Casein Kinase-1 Alpha Using Virtual Screening and Molecular Dynamics Simulations by Shafie, Alaa, Khan, Shama, Zehra, Mohammad, Taj, Anjum, Farah, Hasan, Gulam Mustafa, Yadav, Dharmendra Kumar, Hassan, Md Imtaiyaz

“…Casein kinase-1 alpha (CK1α) is a multifunctional protein kinase that belongs to the serine/threonine kinases of the CK1α family. It is involved in various…”
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Discovery of Hordenine as a Potential Inhibitor of Pyruvate Dehydrogenase Kinase 3: Implication in Lung Cancer Therapy by Anwar, Saleha, Mohammad, Taj, Shamsi, Anas, Queen, Aarfa, Parveen, Shahnaz, Luqman, Suaib, Hasan, Gulam Mustafa, Alamry, Khalid A, Azum, Naved, Asiri, Abdullah M, Hassan, Md Imtaiyaz

“…Design and development of potential pyruvate dehydrogenase kinase 3 (PDK3) inhibitors have gained attention because of their possible therapeutic uses in lung…”
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Development and evaluation of thymoquinone-encapsulated chitosan nanoparticles for nose-to-brain targeting: a pharmacoscintigraphic study by Alam, Sanjar, Khan, Zeenat I, Mustafa, Gulam, Kumar, Manish, Islam, Fakhrul, Bhatnagar, Aseem, Ahmad, Farhan J

“…Chitosan (CS) nanoparticles of thymoquinone (TQ) were prepared by the ionic gelation method and are characterized on the basis of surface morphology, in vitro…”
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