Search Results - "Mustaev, A"

Growth‐inhibitory activity of natural and synthetic isothiocyanates against representative human microbial pathogens by Kurepina, N., Kreiswirth, B.N., Mustaev, A.

“…Aims The aim of this study was to test the growth inhibition activity of isothiocyanates (ITCs), defence compounds of plants, against common human microbial…”
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Structure and Function of Lineage-specific Sequence Insertions in the Bacterial RNA Polymerase β′ Subunit by Chlenov, Mark, Masuda, Shoko, Murakami, Katsuhiko S., Nikiforov, Vadim, Darst, Seth A., Mustaev, Arkady

“…The large β and β′ subunits of the bacterial core RNA polymerase (RNAP) are highly conserved throughout evolution. Nevertheless, large sequence insertions in β…”
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The phage N4 virion RNA polymerase catalytic domain is related to single-subunit RNA polymerases by Kazmierczak, K.M., Davydova, E.K., Mustaev, A.A., Rothman-Denes, L.B.

“…In vitro, bacteriophage N4 virion RNA polymerase (vRNAP) recognizes in vivo sites of transcription initiation on single‐stranded templates. N4 vRNAP promoters…”
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Protein-RNA Interactions in the Active Center of Transcription Elongation Complex by Markovtsov, Vadim, Mustaev, Arkady, Goldfarb, Alex

“…By using a crosslinkable probe incorporated into the 3′ terminus of nascent transcript, three sites were mapped in Escherichia coli RNA polymerase that are…”
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A zinc-binding site in the largest subunit of DNA-dependent RNA polymerase is involved in enzyme assembly by Markov, D, Naryshkina, T, Mustaev, A, Severinov, K

“…All multisubunit DNA-dependent RNA polymerases (RNAP) are zinc metalloenzymes, and at least two zinc atoms are present per enzyme molecule. RNAP residues…”
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Oil content and lipid composition of safflower (Carthamus tinctorius) irrigated with saline water under greenhouse and field conditions by Yuldasheva, N.K, Ul'chenko, N.T, Bekker, N.P, Chernenko, T.V, Glushenkova, A.I, Mustaev, F.A, Ionov, M.V, Heuer, B

“…An intensive process of land deterioration of some regions in Uzbekistan including the Aral Sea basin has led to a significant increase in soil salinity levels…”
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Identification of the Magnesium Ion Binding Site in the Catalytic Center of Escherichia coli Primase by Iron Cleavage by Godson, G. Nigel, Schoenich, Jurek, Sun, Wuliang, Mustaev, A. Arkady

“…Magnesium is essential for the catalysis reaction of Escherichia coli primase, the enzyme synthesizing primer RNA chains for initiation of DNA replication. To…”
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Mechanistic model of the elongation complex of Escherichia coli RNA polymerase by Korzheva, N, Mustaev, A, Nudler, E, Nikiforov, V, Goldfarb, A

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Studies of the Functional Topography of the Catalytic Center of Escherichia coli Primase (∗) by Mustaev, Arkady A., Godson, G. Nigel

“…The catalytic center of E. coli primase (581 amino acids) was identified by using, in the G4oric single-strand binding protein (SSB) primer RNA (pRNA)…”
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The sigma subunit conserved region 3 is part of "5'-face" of active center of Escherichia coli RNA polymerase by SEVERINOV, K, FENYÖ, D, SEVERINOVA, E, ARKADY MUSTAEV, CHAIT, B. T, GOLDFARB, A, DARST, S. A

“…Ribonucleotide analogs bound in the initiating site of Escherichia coli RNA polymerase holoenzyme in open promoter complexes were cross-linked to the beta and…”
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Mapping of the priming substrate contacts in the active center of Escherichia coli RNA polymerase by MUSTAEV, A, KASHLEV, M, JOOKYUNG LEE, POLYAKOV, A, LEBEDEV, A, ZALENSKAYA, K, GRACHEV, M, GOLDFARB, A, NIKIFOROV, V

“…The active center of DNA-dependent RNA polymerase performs the principal biochemical reaction of gene expression. Using cross-linkable substrate analogs and…”
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Mapping the active site of yeast RNA polymerase B (II) by Riva, M, Carles, C, Sentenac, A, Grachev, M A, Mustaev, A A, Zaychikov, E F

“…Yeast RNA polymerase B (II) was incubated with a collection of 13 different nucleotide derivatives and affinity labeled by allowing DNA-directed phosphodiester…”
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ATP Cross-Linked to Escherichia coli Single-Strand DNA-Binding Protein Can Be Utilized by the Catalytic Center of Primase as Initiating Nucleotide for Primer RNA Synthesis on Phage G4oric Template by Godson, G. Nigel, Mustaev, A. Arkady, Sun, Wuliang

“…We report a new observation of the role of Escherichia coli single-strand DNA binding protein (SSB) in synthesis of primer RNA (pRNA) catalyzed by E. coli…”
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Topology of the RNA Polymerase Active Center Probed by Chimeric Rifampicin-Nucleotide Compounds by Mustaev, Arkady, Zaychikov, Evgeny, Severinov, Konstatin, Kashlev, Mikhail, Polyakov, Andrey, Nikiforov, Vadim, Goldfarb, Alex

“…Spatial organization of the binding sites for the priming substrate, the template DNA, and the transcription inhibitor rifampicin (Rif) in Escherichia coli RNA…”
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Assembly of Functional Escherichia coli RNA Polymerase Containing β Subunit Fragments by Severinov, Konstantin, Mustaev, Arkady, Severinova, Elena, Bass, Irina, Kashlev, Mikhail, Landick, Robert, Nikiforov, Vadim, Goldfarb, Alex, Darst, Seth A.

“…The Escherichia coli rpoB gene, which codes for the 1342-residue β subunit of RNA polymerase (RNAP), contains two dispensable regions centered around codons…”
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A Ratchet Mechanism of Transcription Elongation and Its Control by Bar-Nahum, Gil, Epshtein, Vitaly, Ruckenstein, Andrei E., Rafikov, Ruslan, Mustaev, Arkady, Nudler, Evgeny

“…RNA chain elongation is a highly processive and accurate process that is finely regulated by numerous intrinsic and extrinsic signals. Here we describe a…”
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Structural Mechanism for Rifampicin Inhibition of Bacterial RNA Polymerase by Campbell, Elizabeth A., Korzheva, Nataliya, Mustaev, Arkady, Murakami, Katsuhiko, Nair, Satish, Goldfarb, Alex, Darst, Seth A.

“…Rifampicin (Rif) is one of the most potent and broad spectrum antibiotics against bacterial pathogens and is a key component of anti-tuberculosis therapy,…”
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Active center rearrangement in RNA polymerase initiation complex by MUSTAEV, A, KASHLEV, M, ZAYCHIKOV, E, GRACHEV, M, GOLDFARB, A

“…His1237 in the beta subunit of Escherichia coli RNA polymerase marks the "5' face" of the active center since it can be cross-linked to the gamma-phosphate of…”
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Active site labeling of the RNA polymerases A, B, and C from yeast by Riva, M, Schäffner, A R, Sentenac, A, Hartmann, G R, Mustaev, A A, Zaychikov, E F, Grachev, M A

“…RNA polymerases A, B, and C from yeast were modified by reaction with 4-formylphenyl-gamma-ester of ATP as priming nucleotide followed by reduction with NaBH4…”
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Dissection of the beta subunit in the Escherichia coli RNA polymerase into domains by proteolytic cleavage by SEVERINOV, K, MUSTAEV, A, KASHLEV, M, BORUKHOV, S, NIKIFOROV, V, GOLDFARB, A

“…The 1342 amino acid long beta subunit of Escherichia coli RNA polymerase includes a dispensable region (residues 940-1040) that is absent in homologous RNA…”
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