Search Results - "Mussolin, Lara"
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Abrupt Relapse of ALK-Positive Lymphoma after Discontinuation of Crizotinib
Published in The New England journal of medicine (07-01-2016)“…ALK-directed therapy is effective in ALK -positive lymphomas, but the appropriate duration of therapy is unclear. In two patients in whom crizotinib was…”
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Non-Hodgkin Lymphoma in Children and Adolescents: Progress Through Effective Collaboration, Current Knowledge, and Challenges Ahead
Published in Journal of clinical oncology (20-09-2015)“…Non-Hodgkin lymphoma is the fourth most common malignancy in children, has an even higher incidence in adolescents, and is primarily represented by only a few…”
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Crizotinib in Advanced, Chemoresistant Anaplastic Lymphoma Kinase―Positive Lymphoma Patients
Published in JNCI : Journal of the National Cancer Institute (01-02-2014)“…Anaplastic lymphoma kinase (ALK)-positive lymphomas respond to chemotherapy, but relapses, which bear a poor prognosis, occur. Crizotinib inhibits ALK in vitro…”
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BCAT1 is a NOTCH1 target and sustains the oncogenic function of NOTCH1
Published in Haematologica (Roma) (05-09-2024)“…High levels of branched-chain amino acid (BCAA) transaminase 1 (BCAT1) have been associated with tumor aggressiveness and drug resistance in several cancer…”
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microRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas
Published in Proceedings of the National Academy of Sciences - PNAS (03-06-2014)“…Burkitt lymphoma (BL) is a highly aggressive B-cell non-Hodgkin lymphoma (B-NHL), which originates from germinal center (GC) B cells and harbors translocations…”
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Quantitative Plasma Proteomics to Identify Candidate Biomarkers of Relapse in Pediatric/Adolescent Hodgkin Lymphoma
Published in International journal of molecular sciences (31-08-2022)“…Classical pediatric Hodgkin Lymphoma (HL) is a rare malignancy. Therapeutic regimens for its management may be optimized by establishing treatment response…”
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miR-939 acts as tumor suppressor by modulating JUNB transcriptional activity in pediatric anaplastic large cell lymphoma
Published in Haematologica (Roma) (01-02-2021)Get full text
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Early assessment of minimal residual disease identifies patients at very high relapse risk in NPM-ALK–positive anaplastic large-cell lymphoma
Published in Blood (16-01-2014)“…Detection of minimal disseminated disease (MDD) at diagnosis correlates with relapse risk in children with anaplastic lymphoma kinase (ALK)-positive anaplastic…”
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Epstein-Barr virus BART microRNAs in EBV- associated Hodgkin lymphoma and gastric cancer
Published in Infectious agents and cancer (23-06-2020)“…EBV produces miRNAs with important functions in cancer growth, tumor invasion and host immune surveillance. The discovery of EBV miR-BARTs is recent, and most…”
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Proteomic Profiles and Biological Processes of Relapsed vs. Non-Relapsed Pediatric Hodgkin Lymphoma
Published in International journal of molecular sciences (22-03-2020)“…The identification of circulating proteins associated with relapse in pediatric Hodgkin lymphoma (HL) may help develop predictive biomarkers. We previously…”
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Classical Hodgkin’s Lymphoma in the Era of Immune Checkpoint Inhibition
Published in Journal of clinical medicine (02-10-2019)“…The ligation of programmed cell death 1 (PD-1) with programmed cell death ligand PD-L activates the immune checkpoint leading to T-cell dysfunction,…”
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Phosphoproteomic Analysis Reveals a Different Proteomic Profile in Pediatric Patients With T-Cell Lymphoblastic Lymphoma or T-Cell Acute Lymphoblastic Leukemia
Published in Frontiers in oncology (08-07-2022)“…T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) arise from the transformation of precursor T-cells sharing common morphological and…”
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A high definition picture of key genes and pathways mutated in pediatric follicular lymphoma
Published in Haematologica (Roma) (01-09-2019)Get full text
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MiR-26a-5p as a Reference to Normalize MicroRNA qRT-PCR Levels in Plasma Exosomes of Pediatric Hematological Malignancies
Published in Cells (Basel, Switzerland) (08-01-2021)“…Plasma exosomal microRNAs (miRNAs) are considered as valid circulating biomarkers for cancer diagnosis and prognosis. Quantitative real-time polymerase chain…”
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Primary breast lymphoma of childhood: a case report and review of literature
Published in BMC pediatrics (30-11-2021)“…Abstract Background Primary breast lymphoma (PBL) is an extremely rare neoplasm in children; by definition, it manifests in the breast without evidence of…”
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RNY4 in Circulating Exosomes of Patients With Pediatric Anaplastic Large Cell Lymphoma: An Active Player?
Published in Frontiers in oncology (27-02-2020)“…Emerging evidence indicates that extracellular vesicles, particularly exosomes, play a role in several biological processes and actively contribute to cancer…”
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Preliminary Study of the Relationship between Osteopontin and Relapsed Hodgkin's Lymphoma
Published in Biomedicines (01-01-2024)“…The primary objective of this study was to investigate the potential role of tissue osteopontin, also known as secreted phosphoprotein 1 ( ), as a contributing…”
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Low miR-214-5p Expression Correlates With Aggressive Subtypes of Pediatric ALCL With Non-Common Histology
Published in Frontiers in oncology (25-05-2021)“…The unsatisfactory cure rate of relapsing ALK-positive Anaplastic Large-Cell Lymphoma (ALCL) of childhood calls for the identification of new prognostic…”
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Proteomic Exploration of Plasma Exosomes and Other Small Extracellular Vesicles in Pediatric Hodgkin Lymphoma: A Potential Source of Biomarkers for Relapse Occurrence
Published in Diagnostics (Basel) (21-05-2021)“…Exosomes and other small extracellular vesicles (EVs) are potential sources of cancer biomarkers. Plasma-derived EVs have not yet been studied in pediatric…”
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