Search Results - "Musset, Boris"

Voltage-Gated Proton Channels in the Tree of Life by Chaves, Gustavo, Jardin, Christophe, Derst, Christian, Musset, Boris

“…With a single gene encoding H 1 channel, proton channel diversity is particularly low in mammals compared to other members of the superfamily of voltage-gated…”
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Hydrophobic gasket mutation produces gating pore currents in closed human voltage-gated proton channels by Banh, Richard, Cherny, Vladimir V., Morgan, Deri, Musset, Boris, Thomas, Sarah, Kulleperuma, Kethika, Smith, Susan M. E., Pomès, Régis, DeCoursey, Thomas E.

“…The hydrophobic gasket (HG), a ring of hydrophobic amino acids in the voltage-sensing domain of most voltage-gated ion channels, forms a constriction between…”
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Aspartate 112 is the selectivity filter of the human voltage-gated proton channel by Musset, Boris, Smith, Susan M. E., Rajan, Sindhu, Morgan, Deri, Cherny, Vladimir V., DeCoursey, Thomas E.

“…Aspartate key to proton selectivity Voltage-gated proton channels are considered completely selective for protons — no evidence exists for the permeation of…”
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Zinc accelerates respiratory burst termination in human PMN by Droste, Annika, Chaves, Gustavo, Stein, Stefan, Trzmiel, Annette, Schweizer, Matthias, Karl, Hubert, Musset, Boris

“…The respiratory burst of phagocytes is essential for human survival. Innate immune defence against pathogens relies strongly on reactive oxygen species (ROS)…”
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Voltage‐gated proton channels in polyneopteran insects by Chaves, Gustavo, Derst, Christian, Jardin, Christophe, Franzen, Arne, Musset, Boris

“…Voltage‐gated proton channels (HV1) are expressed in eukaryotes, including basal hexapods and polyneopteran insects. However, currently, there is little known…”
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Tryptophan 207 is crucial to the unique properties of the human voltage-gated proton channel, hHV1 by Cherny, Vladimir V, Morgan, Deri, Musset, Boris, Chaves, Gustavo, Smith, Susan M E, DeCoursey, Thomas E

“…Part of the "signature sequence" that defines the voltage-gated proton channel (H(V1)) is a tryptophan residue adjacent to the second Arg in the S4…”
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Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis by Morgan, Deri, Capasso, Melania, Musset, Boris, Cherny, Vladimir V, Ríos, Eduardo, Dyer, Martin J.S, DeCoursey, Thomas E

“…Phagocytosis of microbial invaders represents a fundamental defense mechanism of the innate immune system. The subsequent killing of microbes is initiated by…”
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Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells by Hondares, Elayne, Brown, Mark Adrian, Musset, Boris, Morgan, Deri, Cherny, Vladimir V., Taubert, Christina, Bhamrah, Mandeep K., Coe, David, Marelli-Berg, Federica, Gribben, John G., Dyer, Martin J. S., DeCoursey, Thomas E., Capasso, Melania

“…HVCN1 (Hydrogen voltage-gated channel 1) is the only mammalian voltage-gated proton channel. In human B lymphocytes, HVCN1 associates with the B-cell receptor…”
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Identification of an HV1 voltage‐gated proton channel in insects by Chaves, Gustavo, Derst, Christian, Franzen, Arne, Mashimo, Yuta, Machida, Ryuichiro, Musset, Boris

“…The voltage‐gated proton channel 1 (HV1) is an important component of the cellular proton extrusion machinery and is essential for charge compensation during…”
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Voltage-gated proton channel in a dinoflagellate by Smith, Susan M. E, Morgan, Deri, Musset, Boris, Cherny, Vladimir V, Place, Allen R, Hastings, J. Woodland, DeCoursey, Thomas E

“…Fogel and Hastings first hypothesized the existence of voltage-gated proton channels in 1972 in bioluminescent dinoflagellates, where they were thought to…”
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Selectivity Mechanism of the Voltage-gated Proton Channel, HV1 by Dudev, Todor, Musset, Boris, Morgan, Deri, Cherny, Vladimir V., Smith, Susan M. E., Mazmanian, Karine, DeCoursey, Thomas E., Lim, Carmay

“…Voltage-gated proton channels, H V 1, trigger bioluminescence in dinoflagellates, enable calcification in coccolithophores and play multifarious roles in human…”
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Construction and validation of a homology model of the human voltage-gated proton channel hHV1 by Kulleperuma, Kethika, Smith, Susan M E, Morgan, Deri, Musset, Boris, Holyoake, John, Chakrabarti, Nilmadhab, Cherny, Vladimir V, DeCoursey, Thomas E, Pomès, Régis

“…The topological similarity of voltage-gated proton channels (H(V)1s) to the voltage-sensing domain (VSD) of other voltage-gated ion channels raises the central…”
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Zinc inhibition of monomeric and dimeric proton channels suggests cooperative gating by Musset, Boris, Smith, Susan M. E., Rajan, Sindhu, Cherny, Vladimir V., Sujai, Sukrutha, Morgan, Deri, DeCoursey, Thomas E.

“…Voltage‐gated proton channels are strongly inhibited by Zn2+, which binds to His residues. However, in a molecular model, the two externally accessible His are…”
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Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hHV1 by Morgan, Deri, Musset, Boris, Kulleperuma, Kethika, Smith, Susan M E, Rajan, Sindhu, Cherny, Vladimir V, Pomès, Régis, DeCoursey, Thomas E

“…Extraordinary selectivity is crucial to all proton-conducting molecules, including the human voltage-gated proton channel (hHV1), because the proton…”
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Strong glucose dependence of electron current in human monocytes by Musset, Boris, Cherny, Vladimir V, DeCoursey, Thomas E

“…Reactive oxygen species (ROS) production by human monocytes differs profoundly from that by neutrophils and eosinophils in its dependence on external media…”
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A pH-Stabilizing Role of Voltage-Gated Proton Channels in IgE-Mediated Activation of Human Basophils by Musset, Boris, Morgan, Deri, Cherny, Vladimir V., MacGlashan, Donald W., Thomas, Larry L., Rios, Eduardo, DeCoursey, Thomas E.

“…Eosinophils and other phagocytes use NADPH oxidase to kill bacteria. Proton channels in human eosinophils and neutrophils are thought to sustain NADPH oxidase…”
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The intimate and mysterious relationship between proton channels and NADPH oxidase by Musset, Boris, Cherny, Vladimir V., Morgan, Deri, DeCoursey, Thomas E.

“…Voltage gated proton channels and NADPH oxidase function cooperatively in phagocytes during the respiratory burst, when reactive oxygen species are produced to…”
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Extracellular ATP Induces Oscillations of Intracellular Ca2+and Membrane Potential and Promotes Transcription of IL-6 in Macrophages by Hanley, Peter J., Musset, Boris, Renigunta, Vijay, Limberg, Sven H., Dalpke, Alexander H., Sus, Rainer, Heeg, Klaus M., Preisig-Müller, Regina, Daut, Jürgen, Neher, Erwin

“…The effects of low concentrations of extracellular ATP on cytosolic Ca2+, membrane potential, and transcription of IL-6 were studied in monocyte-derived human…”
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“Host Tissue Damage” Signal ATP Promotes Non-directional Migration and Negatively Regulates Toll-like Receptor Signaling in Human Monocytes by Kaufmann, Andreas, Musset, Boris, Limberg, Sven H., Renigunta, Vijay, Sus, Rainer, Dalpke, Alexander H., Heeg, Klaus M., Robaye, Bernard, Hanley, Peter J.

“…The activation of Toll-like receptors (TLRs) by lipopolysaccharide or other ligands evokes a proinflammatory immune response, which is not only capable of…”
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Effects of divalent cations and spermine on the K+ channel TASK-3 and on the outward current in thalamic neurons by Musset, Boris, Meuth, Sven G., Liu, Gong Xin, Derst, Christian, Wegner, Sven, Pape, Hans‐Christian, Budde, Thomas, Preisig‐Müller, Regina, Daut, Jürgen

“…The potassium channels TASK-1 and TASK-3 show high sequence homology but differ in their sensitivity to extracellular divalent cations. Heterologous expression…”
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