Search Results - "Mussard, Julie"
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Durable and controlled depletion of neutrophils in mice
Published in Nature communications (02-06-2020)“…Neutrophils are an essential part of the innate immune system. To study their importance, experimental studies often aim to deplete these cells, generally by…”
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Neutrophil Heterogeneity in Cancer: From Biology to Therapies
Published in Frontiers in immunology (20-09-2019)“…Neutrophils have been extensively described in the pathophysiology of autoimmune and infectious diseases. Accumulating evidence also suggests the important…”
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BAD-LAMP controls TLR9 trafficking and signalling in human plasmacytoid dendritic cells
Published in Nature communications (13-10-2017)“…Toll-like receptors (TLR) are essential components of the innate immune system. Several accessory proteins, such as UNC93B1, are required for transport and…”
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4
Extracellular Chromatin Triggers Release of Soluble CEACAM8 Upon Activation of Neutrophils
Published in Frontiers in immunology (14-06-2019)“…Increased concentrations of extracellular chromatin are observed in cancer, sepsis, and inflammatory autoimmune diseases like systemic lupus erythematosus…”
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Increased Concentrations of Circulating Soluble MHC Class I-Related Chain A (sMICA) and sMICB and Modulation of Plasma Membrane MICA Expression: Potential Mechanisms and Correlation With Natural Killer Cell Activity in Systemic Lupus Erythematosus
Published in Frontiers in immunology (03-05-2021)“…Systemic lupus erythematosus (SLE) is a severe autoimmune disease of unknown etiology. The major histocompatibility complex (MHC) class I-related chain A…”
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Primary blood neutrophils express a functional cell surface Toll‐like receptor 9
Published in European journal of immunology (01-08-2013)“…Polymorphonuclear leukocytes (PMNs) represent one of the first lines of defense against pathogens. TLR9 is normally expressed in endosomes/lysosomes where it…”
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Type 1 conventional dendritic cells and interferons are required for spontaneous CD4+ and CD8+ T‐cell protective responses to breast cancer
Published in Clinical & translational immunology (2021)“…Objectives To better understand how immune responses may be harnessed against breast cancer, we investigated which immune cell types and signalling pathways…”
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Neutrophil extracellular traps exert both pro- and anti-inflammatory actions in rheumatoid arthritis that are modulated by C1q and LL-37
Published in Journal of autoimmunity (01-03-2019)“…Neutrophil extracellular traps (NET), produced by activated polymorphonuclear neutrophils (PMN), are supposed to play a role in the pathogenesis of rheumatoid…”
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TLR9 independent interferon α production by neutrophils on NETosis in response to circulating chromatin, a key lupus autoantigen
Published in Annals of the rheumatic diseases (01-12-2014)“…Interferon (IFN) α is a key immunoregulatory cytokine secreted by activated plasmacytoid dendritic cells (PDC) that constitute less than 1% of leucocytes. IFNα…”
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Adrenomedullin, a neuropeptide with immunoregulatory properties induces semi‐mature tolerogenic dendritic cells
Published in Immunology (01-06-2012)“…Summary Dendritic cells (DC) play a pivotal role in tolerance. Adrenomedullin (AM), a neuropeptide with anti‐apoptotic and anti‐inflammatory effects, may…”
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Primary blood neutrophils express a functional cell surface T oll‐like receptor 9
Published in European journal of immunology (01-08-2013)“…Polymorphonuclear leukocytes ( PMN s) represent one of the first lines of defense against pathogens. TLR 9 is normally expressed in endosomes/lysosomes where…”
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