Search Results - "Musoro, Godfrey"

Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa by Hakim, James, Musiime, Victor, Szubert, Alex J, Mallewa, Jane, Siika, Abraham, Agutu, Clara, Walker, Simon, Pett, Sarah L, Bwakura-Dangarembizi, Mutsa, Lugemwa, Abbas, Kaunda, Symon, Karoney, Mercy, Musoro, Godfrey, Kabahenda, Sheila, Nathoo, Kusum, Maitland, Kathryn, Griffiths, Anna, Thomason, Margaret J, Kityo, Cissy, Mugyenyi, Peter, Prendergast, Andrew J, Walker, A. Sarah, Gibb, Diana M

“…High mortality is associated with initiation of antiretroviral therapy for HIV. In this report from sub-Saharan Africa, enhanced prophylaxis with isoniazid,…”
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New Insights on Long-Term Hepatitis B Virus Responses in HIV–Hepatitis B virus Co-infected Patients: Implications for Antiretroviral Management in Hepatitis B virus-Endemic Settings by Dunn, David, Price, Huw, Vudriko, Tobias, Kityo, Cissy, Musoro, Godfrey, Hakim, James, Gilks, Charles, Kaleebu, Pontiano, Pillay, Deenan, Gilson, Richard

“…WHO treatment guidelines recommend tenofovir plus lamivudine or emtricitabine as the nucleoside reverse transcriptase inhibitor backbone in first-line regimens…”
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Changes over time in creatinine clearance and comparison of emergent adverse events for HIV-positive adults receiving standard doses (300 mg/day) of lamivudine-containing antiretroviral therapy with baseline creatinine clearance of 30-49 vs ≥50 mL/min by Ross, Lisa L, Walker, A Sarah, Lou, Yu, Tenorio, Allan R, Gibb, Diana M, Double, Julia, Gilks, Charles, McCoig, Cynthia C, Munderi, Paula, Musoro, Godfrey, Kityo, Cissy M, Grosskurth, Heiner, Hakim, James, Mugyenyi, Peter N, Cutrell, Amy, Perger, Teodora, Shaefer, Mark S

“…A retrospective analysis of the randomized controlled DART (Development of AntiRetroviral Therapy in Africa; ISRCTN13968779) trial in HIV-1-positive adults…”
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OA-225 Optimising second line anchor drug options for children with HIV in Africa: 96 week results of the CHAPAS-4 randomised trial by Lugemwa, Abbas, Szubert, Alexander J, Ndebele, Wedu, Walker, Sarah, Turkova, Anna, Tafeni, Sue, Siziba, Grace, Shakeshaft, Clare, Nduna, Bwendo, Nazzinda, Rashida, Nambi, Esether, Mwamabazi, Mwate, Musoro, Godfrey, Musiime, Victor, Mulenga, Veronica, Mujuru, Hilda, McIlleron, Helen, Makumbi, Shafic, Lungu, Joyce, Kityo, Cissy, Dudakia, Nimisha, Doerholt, Katja, Chabala, Chishala, Bwakura-Dangarembizi, Mutsa, Bamford, Alasdair, Gibb, Diana M

“…BackgroundPaediatric second line antiretroviral therapy (ART) formulations are limited. CHAPAS-4 (ISRCTN22964075), a 2X4 factorial randomised trial…”
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Dolutegravir as First- or Second-Line Treatment for HIV-1 Infection in Children by Turkova, Anna, White, Ellen, Mujuru, Hilda A, Kekitiinwa, Adeodata R, Kityo, Cissy M, Violari, Avy, Lugemwa, Abbas, Cressey, Tim R, Musoke, Philippa, Variava, Ebrahim, Cotton, Mark F, Archary, Moherndran, Puthanakit, Thanyawee, Behuhuma, Osee, Kobbe, Robin, Welch, Steven B, Bwakura-Dangarembizi, Mutsa, Amuge, Pauline, Kaudha, Elizabeth, Barlow-Mosha, Linda, Makumbi, Shafic, Ramsagar, Nastassja, Ngampiyaskul, Chaiwat, Musoro, Godfrey, Atwine, Lorna, Liberty, Afaaf, Musiime, Victor, Bbuye, Dickson, Ahimbisibwe, Grace M, Chalermpantmetagul, Suwalai, Ali, Shabinah, Sarfati, Tatiana, Wynne, Ben, Shakeshaft, Clare, Colbers, Angela, Klein, Nigel, Bernays, Sarah, Saïdi, Yacine, Coelho, Alexandra, Grossele, Tiziana, Compagnucci, Alexandra, Giaquinto, Carlo, Rojo, Pablo, Ford, Deborah, Gibb, Diana M

“…In an open-label, randomized, noninferiority trial, dolutegravir-based antiretroviral therapy was compared with standard care in children and adolescents…”
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Benefits of enhanced infection prophylaxis at antiretroviral therapy initiation by cryptococcal antigen status by Pett, Sarah L., Spyer, Moira, Haddow, Lewis J., Nhema, Ruth, Benjamin, Laura A., Najjuka, Grace, Bilima, Sithembile, Daud, Ibrahim, Musoro, Godfrey, Kitabalwa, Juliet, Selemani, George, Kandie, Salome, Cornelius, K. Magut, Katemba, Chrispus, Berkley, Jay A., Hassan, Amin S., Kityo, Cissy, Hakim, James, Heyderman, Robert S., Gibb, Diana M., Walker, Ann S.

“…OBJECTIVES:To assess baseline prevalence of cryptococcal antigen (CrAg) positivity; and its contribution to reductions in all-cause mortality, deaths from…”
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Dolutegravir dosing for children with HIV weighing less than 20 kg: pharmacokinetic and safety substudies nested in the open-label, multicentre, randomised, non-inferiority ODYSSEY trial by Waalewijn, Hylke, Chan, Man K, Bollen, Pauline D J, Mujuru, Hilda A, Makumbi, Shafic, Kekitiinwa, Adeodata R, Kaudha, Elizabeth, Sarfati, Tatiana, Musoro, Godfrey, Nanduudu, Annet, Lugemwa, Abbas, Amuge, Pauline, Moore, Cecilia L, Rojo, Pablo, Giaquinto, Carlo, Colbers, Angela, Gibb, Diana M, Ford, Deborah, Turkova, Anna, Burger, David M

“…Dolutegravir-based antiretroviral therapy is a preferred first-line treatment for adults and children living with HIV; however, very little pharmacokinetic…”
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Raltegravir-intensified initial antiretroviral therapy in advanced HIV disease in Africa: A randomised controlled trial by Kityo, Cissy, Szubert, Alexander J, Siika, Abraham, Heyderman, Robert, Bwakura-Dangarembizi, Mutsa, Lugemwa, Abbas, Mwaringa, Shalton, Griffiths, Anna, Nkanya, Immaculate, Kabahenda, Sheila, Wachira, Simon, Musoro, Godfrey, Rajapakse, Chatu, Etyang, Timothy, Abach, James, Spyer, Moira J, Wavamunno, Priscilla, Nyondo-Mipando, Linda, Chidziva, Ennie, Nathoo, Kusum, Klein, Nigel, Hakim, James, Gibb, Diana M, Walker, A Sarah, Pett, Sarah L

“…In sub-Saharan Africa, individuals infected with HIV who are severely immunocompromised have high mortality (about 10%) shortly after starting antiretroviral…”
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Simplified dolutegravir dosing for children with HIV weighing 20 kg or more: pharmacokinetic and safety substudies of the multicentre, randomised ODYSSEY trial by Bollen, Pauline D J, Moore, Cecilia L, Mujuru, Hilda A, Makumbi, Shafic, Kekitiinwa, Adeodata R, Kaudha, Elisabeth, Parker, Anna, Musoro, Godfrey, Nanduudu, Annet, Lugemwa, Abbas, Amuge, Pauline, Hakim, James G, Rojo, Pablo, Giaquinto, Carlo, Colbers, Angela, Gibb, Diana M, Ford, Deborah, Turkova, Anna, Burger, David M

“…Paediatric dolutegravir doses approved by stringent regulatory authorities (SRAs) for children weighing 20 kg to less than 40 kg until recently required 25 mg…”
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Prevalence, incidence and predictors of peripheral neuropathy in African adults with HIV infection within the DART trial by KIWUWA-MUYINGO, Sylvia, KIKAIRE, Bernard, MAMBULE, Ivan, MUSANA, Helen, MUSORO, Godfrey, GILKS, Charles F, LEVIN, Jonathan B, WALKER, Anne Sarah

“…We investigated the prevalence, incidence and predictors of new peripheral neuropathy episodes in previously untreated, symptomatic HIV-infected…”
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Changes over time in creatinine clearance and comparison of emergent adverse events for HIV-positive adults receiving standard doses by Ross, Lisa L, Walker, A. Sarah, Lou, Yu, Tenorio, Allan R, Gibb, Diana M, Double, Julia, Gilks, Charles, McCoig, Cynthia C, Munderi, Paula, Musoro, Godfrey, Kityo, Cissy M, Grosskurth, Heiner, Hakim, James, Mugyenyi, Peter N, Cutrell, Amy, Perger, Teodora, Shaefer, Mark S

“…A retrospective analysis of the randomized controlled DART (Development of AntiRetroviral Therapy in Africa; ISRCTN13968779) trial in HIV-1-positive adults…”
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Causes and Timing of Mortality and Morbidity Among Late Presenters Starting Antiretroviral Therapy in the REALITY Trial by Post, Frank A, Szubert, Alexander J, Prendergast, Andrew J, Johnston, Victoria, Lyall, Hermione, Fitzgerald, Felicity, Musiime, Victor, Musoro, Godfrey, Chepkorir, Priscilla, Agutu, Clara, Mallewa, Jane, Rajapakse, Chathurika, Wilkes, Helen, Hakim, James, Mugyenyi, Peter, Walker, A Sarah, Gibb, Diana M, Pett, Sarah L

“…In sub-Saharan Africa, 20%-25% of people starting antiretroviral therapy (ART) have severe immunosuppression; approximately 10% die within 3 months. In the…”
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Peripheral neuropathy in HIV patients in sub-Saharan Africa failing first-line therapy and the response to second-line ART in the EARNEST trial by Arenas-Pinto, Alejandro, Thompson, Jennifer, Musoro, Godfrey, Musana, Hellen, Lugemwa, Abbas, Kambugu, Andrew, Mweemba, Aggrey, Atwongyeire, Dickens, Thomason, Margaret J., Walker, A. Sarah, Paton, Nicholas I.

“…Sensory peripheral neuropathy (PN) remains a common complication in HIV-positive patients despite effective combination anti-retroviral therapy (ART). Data on…”
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Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial by Mallewa, Jane, Szubert, Alexander J, Mugyenyi, Peter, Baleeta, Keith, Etyang, Anthony, Warambwa, Colin, Kelly, Christine, Agutu, Clara, Nkomani, Sanele, Musiime, Victor, Pett, Sarah L, Prendergast, Andrew J, Gibb, Diana M, Walker, A Sarah, Berkley, James A, Kityo, Cissy, Musiime, Victor, Wavamunno, Priscilla, Nambi, Esther, Ocitti, Paul, Ndigendawani, Milly, Acen, Juliet, Mbonye, Andrew, Nambaziira, Florence, Kangah, Mary, Abongomera, George, Aciro, Irene, Philliam, Aleti, Arach, Beatrice, Adong, Claudia, Otto, Ben, Abwola, Mary, Ssennono, Fred, Namisi, Ronald, Kikyonkyo, Dickson, Mushahara, Furaha, Musiime, Alex, Sirikye, Sowal, Myalo, Sula, Lugemwa, Abbas, Kasozi, Mariam, Atwine, Lorna, Natuhurira, Ian, Katemba, Chrispus, Ankunda, Rogers, Tukwasibwe, Deogratious, Ayesiga, Lillian, Hakim, James, Chidziva, Ennie, Tinago, Gloria, Steamer, John, Warambwa, Colin, Vhembo, Sydney, Mlambo, Brian, Ndemera, Buxton, Willard, Marko, Matiza, Patience, Guti, Vongai, Etyang, Anthony, Agutu, Clara, Njuguna, Patricia, Etyang, Timothy, Kithunga, Jefwa, Said Maitha, Salma, Mutai, Robert, Lozi Lewa, Margaret, Fondo, Amos, Njogu, Anne, Mwakisha, Bryan, Sudoi, Allan, Wachira, Simon, Tanui, Michael, Ekiru, Wilson, Mengich, Cecilia, Choge, Julie, Njenga, Kennedy, Anyango Orido, Millicent, Omondi Lwande, Gerald, Rutto, Peter, Mudogo, Alice, Kutto, Irene, Jaika, Linda, Pierre, Mowlem, Mallewa, Jane, Kaunda, Symon, Van Oosterhout, Joep, Heydermann, Robert, Selemani, George, Banda, Peter, Msuku, Harrison, Manda, Yollam, Sheha, Irene, Bwanali, Joseph, Limbuni, Molly, Gibb, Diana M, Walker, Ann Sarah, Rajapakse, Chathurika, Van Looy, Nadine, Bernays, Sarah, Mupambireyi, Zivai

“…In sub-Saharan Africa, severely immunocompromised HIV-infected individuals have a high risk of mortality during the first few months after starting…”
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