Search Results - "Musler, A"

Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates by de Leng, WWJ, Jansen, M, Carvalho, R, Polak, M, Musler, AR, Milne, ANA, Keller, JJ, Menko, FH, de Rooij, FWM, Iacobuzio-Donahue, CA, Giardiello, FM, Weterman, MAJ, Offerhaus, GJA

“…LKB1/STK11 germline inactivations are identified in the majority (66–94%) of Peutz–Jeghers syndrome (PJS) patients. Therefore, defects in other genes or so far…”
Get full text

Chlamydia psittaci-negative ocular adnexal marginal zone B-cell lymphomas have biased VH4-34 immunoglobulin gene expression and proliferate in a distinct inflammatory environment by van Maldegem, F, Wormhoudt, T A M, Mulder, M M S, Oud, M E C M, Schilder-Tol, E, Musler, A R, Aten, J, Saeed, P, Kersten, M J, Pals, S T, van Noesel, C J M, Bende, R J

“…Ocular adnexal marginal zone B-cell lymphomas (OAMZLs) arise in the connective tissues of the orbit or in the mucosa-associated lymphoid tissue of the…”
Get full text

STRAD in Peutz-Jeghers syndrome and sporadic cancers by de Leng, W W J, Keller, J J, Luiten, S, Musler, A R, Jansen, M, Baas, A F, de Rooij, F W M, Gille, J J P, Menko, F H, Offerhaus, G J A, Weterman, M A J

“…Background/Aims:LKB1 is a tumour suppressor gene that is associated with Peutz-Jeghers syndrome (PJS), a rare autosomal dominant cancer predisposition…”
Get full text

Cyclin E low molecular weight isoforms occur commonly in early-onset gastric cancer and independently predict survival by Milne, A N A, Carvalho, R, Jansen, M, Kranenbarg, E K, van de Velde, C J H, Morsink, F M, Musler, A R, Weterman, M A J, Offerhaus, G J A

“…Post-translational cleavage of full-length cyclin E from the N-terminus can produce low molecular weight (LMW) isoforms of cyclin E containing the C-terminus…”
Get more information

Can K-ras codon 12 mutations be used to distinguish benign bile duct proliferations from metastases in the liver? A molecular analysis of 101 liver lesions from 93 patients by Hruban, RH, Sturm, PD, Slebos, RJ, Wilentz, RE, Musler, AR, Yeo, CJ, Sohn, TA, van Velthuysen, ML, Offerhaus, GJ

“…It can be difficult to distinguish benign bile duct proliferations (BDPs) from well-differentiated metastatic peripancreatic adenocarcinomas on histological…”
Get full text

Helicobacter pylori and Epstein-Barr virus infection and the p53 tumour suppressor pathway in gastric stump cancer compared with carcinoma in the non-operated stomach by Baas, I O, van Rees, B P, Musler, A, Craanen, M E, Tytgat, G N, van den Berg, F M, Offerhaus, G J

“…AIM: To evaluate similarities and differences between gastric stump cancer and conventional carcinoma in the non-operated stomach. METHODS: 26 stump carcinomas…”
Get full text

K-ras mutations in gastric stump carcinomas and in carcinomas from the non-operated stomach by van Rees, B P, Musler, A, Caspers, E, Drillenburg, P, Craanen, M E, Polkowski, W, Chibowski, D, Offerhaus, G J

“…Partial gastrectomy is a well-established pre-malignant condition. It is postulated that in the gastric stump an accelerated neoplastic process takes place,…”
Get more information

Effects of processing delay, formalin fixation, and immunohistochemistry on RNA Recovery From Formalin-fixed Paraffin-embedded Tissue Sections by van Maldegem, Febe, de Wit, Mireille, Morsink, Folkert, Musler, Alex, Weegenaar, Jitske, van Noesel, Carel J M

“…Contemporary pathology involves an emerging role for molecular diagnostics. Current tissue handling procedures [ie, formalin fixation and paraffin embedment…”
Get more information

Chlamydia psittaci-negative ocular adnexal marginal zone B-cell lymphomas have biased V sub(H)4-34 immunoglobulin gene expression and proliferate in a distinct inflammatory environment by van Maldegem, F, Wormhoudt, T A M, Mulder, M M S, Oud, M E C M, Schilder-Tol, E, Musler, A R, Aten, J, Saeed, P, Kersten, M J, Pals, S T, van Noesel, C J M, Bende, R J

“…Ocular adnexal marginal zone B-cell lymphomas (OAMZLs) arise in the connective tissues of the orbit or in the mucosa-associated lymphoid tissue of the…”
Get full text

Graft-versus-host-like disease complicating thymoma: Lack of AIRE expression as a cause of non-hereditary autoimmunity? by Offerhaus, G. Johan, Schipper, Marguerite E.I, Lazenby, Audrey J, Montgomery, Elizabeth, Morsink, Folkert H.M, Bende, Richard J, Musler, Alex R, van Lier, Rene A.W, van Noesel, Carel J.M

“…Abstract Three patients with graft-versus-host-like enterocolonopathy are reported. Their history was remarkable for thymoma and other autoimmune…”
Get full text

K‐ras mutations in the duodenal fluid of patients with pancreatic carcinoma by Wilentz, Robb E., Chung, Christine H., Sturm, Patrick D. J., Musler, Alex, Sohn, Taylor A., Offerhaus, G. Johan A., Yeo, Charles J., Hruban, Ralph H., Slebos, Robbert J. C.

“…BACKGROUND Many patients with carcinoma of the pancreas die because their disease is not detected until late in its course. Methods that detect these cancers…”
Get full text

Molecular Analysis of Sulindac-resistant Adenomas in Familial Adenomatous Polyposis by KELLER, Josbert J, OFFERHAUS, G. Johan A, DRILLENBURG, Paul, CASPERS, Eric, MUSLER, Alex, RISTIMÄKI, Ari, GIARDIELLO, Francis M

“…Purpose: Sulindac causes the reduction of adenomas in familial adenomatous polyposis (FAP) patients, but complete regression is unusual, and breakthrough of…”
Get full text

Sulindac resistant adenomas in familial adenomatous polyposis patients: A molecular evaluation by KELLER, J, OFFERHAUS, J, DRILLENBURG, P, CASPERS, E, MUSLER, A

Get full text

The prevalence of K-ras mutations in ductal brush cytology and bile of subjects without pancreatic disease using the epidemiologic necropsy as study design by van Heek, NT, Caspers, E, Tascilar, M, Musler, A, Polak, M, Gouma, DJ, Drillenburg, P, Offerhaus, GJA

Get full text

Cyclooxygenase-2 expression during tumor progression and characterization of cox-2 positive stromal cells in the stomach by VANREES, B, RISTIMAKI, A, SAUKKONEN, K, MORSINK, F, MUSLER, A, CRAANEN, M, DRILLENBURG, P, JOHAN, G, OFFERHAUS, A

Get full text

Early-onset gastric cancers have a different molecular expression profile than conventional gastric cancers by Milne, Anya N A, Carvalho, Ralph, Morsink, Folkert M, Musler, Alex R, de Leng, Wendy W J, Ristimäki, Ari, Offerhaus, G Johan A

“…Many studies examine the molecular genetics of gastric cancer, but few look at young patients in particular and there is no comparison of molecular expression…”
Get full text

Short Report: Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates by de Leng, WWJ, Jansen, M, Carvalho, R, Polak, M, Musler, AR, Milne, ANA, Keller, JJ, Menko, FH, de Rooij, FWM, Iacobuzio-Donahue, CA, Giardiello, FM, Weterman, MAJ, Offerhaus, GJA

“…de Leng WWJ, Jansen M, Carvalho R, Polak M, Musler AR, Milne ANA, Keller JJ, Menko FH, de Rooij FWM, Iacobuzio-Donahue CA, Giardiello FM, Weterman MAJ,…”
Get full text