Search Results - "Muslehiddinoglu, Jale"

The Development of a Scalable, Chemoselective Nitro Reduction by Gallagher, William P, Marlatt, Mark, Livingston, Robert, Kiau, Susanne, Muslehiddinoglu, Jale

“…We have demonstrated a scalable chemoselective reduction of a nitro functional group in the presence of an aryl imine using (NH4)2S/EtOH or hydrogenation…”
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The Process Development of Ravuconazole: An Efficient Multikilogram Scale Preparation of an Antifungal Agent by Pesti, Jaan, Chen, Chien-Kuang, Spangler, Lori, DelMonte, Albert J, Benoit, Serge, Berglund, Derek, Bien, Jeffrey, Brodfuehrer, Paul, Chan, Yeung, Corbett, Elisabeth, Costello, Carrie, DeMena, Paul, Discordia, Robert P, Doubleday, Wendel, Gao, Zhinong, Gingras, Stephane, Grosso, John, Haas, Oscar, Kacsur, David, Lai, Chiajen, Leung, Simon, Miller, Melanie, Muslehiddinoglu, Jale, Nguyen, Nina, Qiu, Jun, Olzog, Martina, Reiff, Emily, Thoraval, Dominique, Totleben, Michael, Vanyo, Dale, Vemishetti, Purushotham, Wasylak, John, Wei, Chenkou

“…The development of a safe, robust process for the preparation of ravuconazole (1), an antifungal agent, is described. The discovery and development of…”
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Stereoselective Bulk Synthesis of CCR2 Antagonist BMS-741672: Assembly of an All- cis ( S,R,R )-1,2,4-Triaminocyclohexane (TACH) Core via Sequential Heterogeneous Asymmetric Hydrogenations by Deerberg, Joerg, Prasad, Siva J., Sfouggatakis, Chris, Eastgate, Martin D., Fan, Yu, Chidambaram, Ramakrishnan, Sharma, Praveen, Li, Li, Schild, Richard, Müslehiddinoğlu, Jale, Chung, Hyei-Jha, Leung, Simon, Rosso, Victor

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Highly Diastereoselective Hydrogenation of Imines by a Bimetallic Pd−Cu Heterogeneous Catalyst by Müslehiddinoğlu, Jale, Li, Jun, Tummala, Srinivas, Deshpande, Rajendra

“…An efficient and practical heterogeneous bimetallic Pd−Cu/C catalyst was identified as an alternative to Raney nickel for the highly diastereoselective…”
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Development of a Practical Synthesis of a Functionalized Pyrrolo[2,1-f][1,2,4]triazine Nucleus by Zheng, Bin, Conlon, David A, Corbett, R. Michael, Chau, Melissa, Hsieh, Dau-Ming, Yeboah, Agnes, Hsieh, Daniel, Müslehiddinoğlu, Jale, Gallagher, William P, Simon, Jeffrey N, Burt, Justin

“…Functionalized pyrrolotriazine 1b is a key heterocyclic building block in the synthesis of BMS-690514, a potent anticancer agent. Described herein are our…”
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Control Strategy for the Manufacture of Brivanib Alaninate, a Novel Pyrrolotriazine VEGFR/FGFR Inhibitor by Lobben, Paul C, Barlow, Evan, Bergum, James S, Braem, Alan, Chang, Shih-Ying, Gibson, Frank, Kopp, Nathaniel, Lai, Chiajen, LaPorte, Thomas L, Leahy, David K, Müslehiddinoğlu, Jale, Quiroz, Fernando, Skliar, Dimitri, Spangler, Lori, Srivastava, Sushil, Wasser, Daniel, Wasylyk, John, Wethman, Robert, Xu, Zhongmin

“…This manuscript describes the control strategy for the commercial process to manufacture brivanib alaninate. The active pharmaceutical ingredient is a prodrug…”
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A kinetic investigation into the removal of carbobenzyloxy group from protected amines via hydrogenolysis reaction by Müslehiddinoğlu, Jale, Lobben, Paul, Leung, Simon, Spangler, Lori, Kiang, San

“…Hydrogenolysis of a carbobenzyloxy group (CBz) was studied utilizing molecular hydrogen in the presence of carbon-supported palladium catalyst. It was…”
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Adsorption of NO on promoted Ag/α-Al2O3 catalysts by MÜSLEHIDDINOGLU, Jale, VANNICE, M. Albert

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Highly Diastereoselective Hydrogenation of Imines by a Bimetallic Pd−Cu Heterogeneous Catalyst by Müslehiddinoǧlu, Jale, Li, Jun, Tummala, Srinivas, Deshpande, Rajendra

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CO adsorption on supported and promoted Ag epoxidation catalysts by Müslehiddinoğlu, Jale, Vannice, M.Albert

“…CO was used to probe the nature of adsorption sites on Ag/ α-Al 2O 3 epoxidation catalysts and to investigate the effect of Cs and Cl promoters by employing…”
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Adsorption of 1,3-butadiene on supported and promoted silver catalysts by Müslehiddinoğlu, Jale, Vannice, M.Albert

“…After exposure to 1,3-butadiene, unpromoted Ag/ α-Al 2O 3 and Ag/ α-Al 2O 3 promoted with Cs and Cl were characterized using DRIFTS. Weakly adsorbed molecular…”
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Development of a Continuous Plug Flow Process for Preparation of a Key Intermediate for Brivanib Alaninate by LaPorte, Thomas L., Spangler, Lori, Hamedi, Mourad, Lobben, Paul, Chan, Steven H., Muslehiddinoglu, Jale, Wang, Steve S. Y.

“…A thermal runaway potential was identified for the conversion of a tertiary alcohol to a hydroxypyrrolotriazine intermediate in the synthesis of brivanib…”
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Effect of operating parameters on selective separation of heavy metals from binary mixtures via polymer enhanced ultrafiltration by Müslehiddinoğlu, Jale, Uludağ, Yusuf, Özbelge, Hilmi Önder, Yilmaz, Levent

“…Performance of continuous polymer enhanced ultrafiltration (PEUF) method was investigated for removal of mercury and cadmium from binary mixtures. This method…”
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European Pharma Oligonucleotide Consortium: A Move to Consolidate Oligonucleotide Knowledge and Share Experience Within the Community by Tivesten, Anna, Akhtar, Nadim, Stolee, Jessica, Fillon, Yannick, Orr, Rachel, Hill, Malcolm L, Van den Bergh, Leo, Huybrechts, Tom, Muslehiddinoglu, Jale, McCormac, Paul, Amery, John, Brecht, Andrea, Geiser, Achim, Metzenthin, Tobias, Eichinger, Thomas

“…A consortium of seven pharma companies has been formed with the aim of sharing knowledge on and harmonizing approaches to oligonucleotide development. This…”
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Characterization of supported and promoted silver epoxidation catalysts using molecular probes by Muslehiddinoglu, Jale

“…Silver supported on low surface area alpha-Al2O3 and promoted with Cs or Cs plus Cl was studied using CO, NO, 1,3-butadiene, and 3,4-epoxy-l-butene as probe…”
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Characterization of supported and promoted silver epoxidation catalysts using molecular probes by Muslehiddinoglu, Jale

“…Silver supported on low surface area α-Al2O3 and promoted with Cs or Cs plus Cl was studied using CO, NO, 1,3-butadiene, and 3,4-epoxy-l-butene as probe…”
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Adsorption of NO on promoted Ag/ α-Al 2O 3 catalysts by Müslehiddinoğlu, Jale, Vannice, M.Albert

“…Nitric oxide was used to probe Ag/ α-Al 2O 3 epoxidation catalysts. NO dissociated on reduced silver catalysts to oxidize metallic silver sites and desorb N 2O…”
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Stereoselective Bulk Synthesis of CCR2 Antagonist BMS-741672: Assembly of an All-cis (S,R,R)‑1,2,4-Triamino­cyclohexane (TACH) Core via Sequential Heterogeneous Asymmetric Hydrogenations by Deerberg, Joerg, Prasad, Siva J, Sfouggatakis, Chris, Eastgate, Martin D, Fan, Yu, Chidambaram, Ramakrishnan, Sharma, Praveen, Li, Li, Schild, Richard, Müslehiddinoğlu, Jale, Chung, Hyei-Jha, Leung, Simon, Rosso, Victor

“…A concise bulk synthesis of stereochemically complex CCR2 antagonist BMS-741672 is reported. A distinct structural feature is the chiral all-cis…”
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Determination of heavy metal concentration in feed and permeate streams of polymer enhanced ultrafiltration process by MÜSLEHIDDINOG, J, ULUDAG, Y, ÖZBELGE, H. O, YILMAZ, L

“…Polymer enhanced ultrafiltration (PEUF) is a newly developed method for the removal of heavy metals from aqueous solutions. This method was applied for the…”
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