Search Results - "Musiyak, V. V."
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Antiviral effect of novel purine conjugate LAS-131 against Herpes simplex virus type 1 (Herpesviridae: Alphaherpesvirinae: Simplexvirus: Human alphaherpesvirus 1) in vitro
Published in Voprosy virusologiĭ (07-01-2021)“…Introduction. Herpes simplex viruses type 1 (HSV-1) are extremely widespread throughout the world and, similar to other herpesviruses, establish lifelong…”
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Synthesis of Pyrimidine Conjugates with 4-(6-Amino-hexanoyl)-7,8-difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine and Evaluation of Their Antiviral Activity
Published in Molecules (Basel, Switzerland) (30-06-2022)“…A series of pyrimidine conjugates containing a fragment of racemic 7,8-difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine and its (S)-enantiomer attached via a…”
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Synthesis and Cytotoxic Activity of the Derivatives of N -(Purin-6-yl)aminopolymethylene Carboxylic Acids and Related Compounds
Published in Molecules (Basel, Switzerland) (15-02-2023)“…Testing a number of -[omega-(purin-6-yl)aminoalkanoyl] derivatives of 7,8-difluoro-3,4-dihydro-3-methyl-2 -[1,4]benzoxazine in a panel of nine tumor cell lines…”
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Synthesis of New Purine Derivatives Containing α- and ω-Amino Acid Fragments
Published in Russian journal of organic chemistry (01-06-2019)“…New conjugates of purine and 2-aminopurine with several α- and ω-amino acids have been synthesized following two approaches based on the condensation and…”
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Analysis of racemic conjugates of purine with heterocyclic amines by chiral high-performance liquid chromatography
Published in Russian chemical bulletin (01-09-2018)“…Reversed-phase HPLC on chiral stationary phases was used to study the influence of the structure of purine and 2-aminopurine conjugates with chiral…”
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Stereochemical aspects in the synthesis of novel N-(purin-6-yl)dipeptides as potential antimycobacterial agents
Published in Amino acids (01-03-2021)“…The synthesis of purine conjugates with natural amino acids is one of the promising directions in search for novel therapeutic agents, including…”
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N‐[ω‐(Purin‐6‐yl)aminoalkanoyl] Derivatives of Chiral Heterocyclic Amines as Promising Anti‐Herpesvirus Agents
Published in European journal of organic chemistry (15-08-2019)“…Novel conjugates of 2‐aminopurine and purine containing fragments of chiral heterocyclic amines attached at position 6 of purine core via a linker, fragment of…”
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Synthesis and antimycobacterial activity of N-(2-aminopurin-6-yl) and N-(purin-6-yl) amino acids and dipeptides
Published in Bioorganic & medicinal chemistry letters (01-06-2016)“…[Display omitted] Synthetic routes to novel N-(purin-6-yl)- and N-(2-aminopurin-6-yl) conjugates with amino acids and glycine-containing dipeptides were…”
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Novel purine conjugates with N-heterocycles: synthesis and anti-influenza activity
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01-04-2021)“…A number of novel amides were synthesized by coupling of 6-[(9 H -purin-6-yl)amino]hexanoic acid to heterocyclic amines. The antiviral activity of the obtained…”
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Intramolecular cyclization of 2-(heteroarylsulfanyl)-N-(3-oxoalkenyl)acetamides: synthesis of 3-(heteroarylsulfanyl)- and 3-sulfanylpyridin-2(1H)-ones
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01-09-2020)“…The reaction of 2-chloro- N -(3-oxoalkenyl)acetamides with 1,3-benzothiazole-2(3 H )-thione, 1,3-benzoxazole-2(3 H )-thione, and 1-methyl-1,3-dihydro-2 H…”
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Synthesis of purine and 2-aminopurine conjugates bearing the fragments of heterocyclic amines at position 6
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01-08-2015)“…A series of novel N -(purin-6-yl)- and N -(2-aminopurin-6-yl) derivatives of heterocyclic amines was synthesized. It was found that preferred preparative…”
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Synthesis and Cytotoxic Activity of the Derivatives of IN/I-aminopolymethylene Carboxylic Acids and Related Compounds
Published in Molecules (Basel, Switzerland) (01-02-2023)“…Testing a number of N-[omega-(purin-6-yl)aminoalkanoyl] derivatives of 7,8-difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine in a panel of nine tumor cell…”
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Synthesis and antimycobacterial activity of purine conjugates with (S)-lysine and (S)-ornithine
Published in Mendeleev communications (01-01-2019)“…[Display omitted] Novel purin-6-yl, 2-aminopurin-6-yl and N-(purin-6-yl)glycyl derivatives of (S)-lysine and (S)-ornithine with free α-functional groups, as…”
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Intramolecular cyclization of 2--ones
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01-09-2020)“…The reaction of 2-chloro-N-(3-oxoalkenyl)acetamides with 1,3-benzothiazole-2(3H)-thione, 1,3-benzoxazole-2(3H)-thione, and…”
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Synthesis of novel purin-6-yl conjugates with heterocyclic amines linked via 6-aminohexanoyl fragment
Published in Mendeleev communications (01-11-2015)“…[Display omitted] Novel conjugates of purine and 2-aminopurine linked with heterocyclic amines, including chiral derivatives of…”
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