Search Results - "Musharbash, Awni"
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BRAF/MEK inhibitors use for pediatric gliomas; real world experience from a resource-limited country
Published in Frontiers in oncology (27-09-2024)“…Most pediatric low-grade-gliomas (LGG) and some high-grade-gliomas (HGG) have alterations in the RAS/MAPK pathway. Promising high tumor response rates were…”
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Next-generation sequencing for pediatric CNS tumors: does it add value in a middle-income country setup?
Published in Frontiers in oncology (19-02-2024)“…Advances in molecular diagnostics led to improved targeted interventions in the treatment of pediatric CNS tumors. However, the capacity to test for these is…”
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Molecular Subgroup Is the Strongest Predictor of Medulloblastoma Outcome in a Resource-Limited Country
Published in JCO global oncology (01-12-2021)“…PURPOSE Medulloblastoma is composed of four clinically and prognostically distinct molecular subgroups (WNT, SHH, group 3, and group 4). However, the clinical…”
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Mondini Malformation Associated With Diastematomyelia and Presenting With Recurrent Meningitis
Published in Journal of child neurology (01-05-2011)“…The authors report the case of 5-year-old girl who presented with 4 episodes of recurrent meningitis. Her initial workup revealed a lumbosacral dermoid sinus…”
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Embryonal tumor with abundant neuropil and true rosettes: a report of three cases of a rare tumor, with an unusual case showing rhabdomyoblastic and melanocytic differentiation
Published in Neuropathology (01-12-2011)“…Embryonal tumor with abundant neuropil and true rosettes (ETANTR) is an increasingly recognized entity that belongs to the family of embryonal tumors of the…”
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Brain stem gliomas: a clinicopathological study from a single cancer center
Published in Brain tumor pathology (01-04-2013)“…Brain stem gliomas (BSG) are rare tumors occurring predominantly in childhood. They are mostly of astrocytic origin and are divided into infiltrative versus…”
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Ataxia-Telangiectasia Complicated by Craniopharyngioma – A New Observation
Published in Pediatric neurology (01-10-2006)“…Ataxia-telangiectasia is a rare autosomal recessive neurodegenerative disorder with high incidence of malignancy including leukemias, lymphomas, and solid…”
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Video-Teleconferencing in Pediatric Neuro-Oncology: Ten Years of Experience
Published in Journal of global oncology (01-09-2018)“…The management of central nervous system tumors is challenging in low- and middle-income countries. Little is known about applicability of twinning initiatives…”
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Descriptive epidemiological analysis, MRI signals intensity and histopathological correlations of meningiomas
Published in Neurosciences (Riyadh, Saudi Arabia) (01-01-2010)“…To present our experience in operated meningioma cases regarding their prevalence, anatomical location, multiplicity, presenting signs and symptoms, and the…”
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PATH-63. NEXT GENERATION SEQUENCING FOR CNS TUMORS IN CHILDREN; DOES IT ADD VALUE IN A MIDDLE-INCOME COUNTRY SETUP?
Published in Neuro-oncology (Charlottesville, Va.) (10-11-2023)“…Abstract INTRODUCTION Advances in molecular diagnostics led to improved targeted interventions in the treatment of pediatric CNS tumors. However, the capacity…”
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High frequency of mismatch repair deficiency among pediatric high grade gliomas in Jordan
Published in International journal of cancer (15-01-2016)“…Biallelic mismatch repair deficiency (bMMRD) is a cancer predisposition syndrome affecting primarily individuals from consanguinous families resulting in…”
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BRAF/MEK inhibitors use to treat ventriculoperitoneal shunt‐associated ascites in pediatric low‐grade gliomas
Published in Pediatric blood & cancer (01-08-2024)Get full text
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SIOP PODC–adapted treatment guidelines for craniopharyngioma in low‐ and middle‐income settings
Published in Pediatric blood & cancer (01-11-2023)“…Abstract Pediatric craniopharyngioma is a rare tumor with excellent survival but significant long‐term morbidities due to the loco‐regional tumor growth or…”
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Sustained Response to Targeted Therapy in a Patient With Disseminated Anaplastic Pleomorphic Xanthoastrocytoma
Published in Journal of pediatric hematology/oncology (01-08-2018)“…Pleomorphic xanthoastrocytoma is a rare brain tumor with unique high frequency of BRAF V600E mutation which is plausible for targeted therapy. The anaplastic…”
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Molecular correlates of cerebellar mutism syndrome in medulloblastoma
Published in Neuro-oncology (Charlottesville, Va.) (20-02-2020)“…Abstract Background Cerebellar mutism syndrome (CMS) is a common complication following resection of posterior fossa tumors, most commonly after surgery for…”
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Who are the high risk medulloblastoma subgroups in Jordan?
Published in Journal of clinical oncology (20-05-2018)“…Abstract only…”
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Feasibility of treating pediatric intracranial germ cell tumors in a middle‐income country: The Jordanian experience
Published in Pediatric blood & cancer (01-12-2022)“…Background Pediatric intracranial germ cell tumors (iGCT) are rare, with limited data available from Arabic countries. Methods We retrospectively reviewed the…”
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DEV-17. WHO ARE THE HIGH RISK MEDULLOBLASTOMA SUBGROUPS IN JORDAN?
Published in Neuro-oncology (Charlottesville, Va.) (22-06-2018)“…Abstract BACKGROUND Medulloblastoma is comprised of four distinct molecular subgroups (WNT, SHH, Group3,Group4) with unique clinical and prognostic…”
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Incidence of second primary cancers with pediatric high grade glioma: Single institution experience
Published in Journal of clinical oncology (20-05-2015)“…Abstract only…”
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Central nervous system tumors in the first year of life: a clinical and pathologic experience from a single cancer center
Published in Child's nervous system (01-10-2013)“…Purpose This study aims to review our experience with central nervous system (CNS) tumors occurring during the first year of life and to report differing…”
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