Search Results - "Musgrove, Lois C"

Cytomegalovirus enhances macrophage TLR expression and MyD88-mediated signal transduction to potentiate inducible inflammatory responses by Smith, Phillip D, Shimamura, Masako, Musgrove, Lois C, Dennis, Evida A, Bimczok, Diane, Novak, Lea, Ballestas, Mary, Fenton, Anne, Dandekar, Satya, Britt, William J, Smythies, Lesley E

“…Circulating monocytes carrying human CMV (HCMV) migrate into tissues, where they differentiate into HCMV-infected resident macrophages that upon interaction…”
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A Gonadotropin-Releasing Hormone (GnRH) Receptor Specific for GnRH II in Primates by Neill, Jimmy D., Duck, L.Wayne, Sellers, Jeffrey C., Musgrove, Lois C.

“…Mammalian gonadotropin-releasing hormone (GnRH I) is a hypothalamic decapeptide that stimulates gonadotropic hormone secretion upon interaction with its…”
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Mutations in gonadotropin-releasing hormone receptor gene cause hypogonadotropic hypogonadism by Layman, Lawrence C, Cohen, David P, Jin, Mei, Xie, Jun, Li, Zhu, Reindollar, Richard H, Bolbolan, Shahla, Bick, David P, Sherins, Richard R, Duck, L. Wayne, Musgrove, Lois C, Sellers, Jeffrey C, Neill, Jimmy D

“…Idiopathic hypogonadotropic hypogonadism (IHH) is one of the most common causes of hereditary hypogonadism. Affected males and females present with…”
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Cloning, sequencing, and expression of human gonadotropin releasing hormone (GnRH) receptor by Kakar, S S, Musgrove, L C, Devor, D C, Sellers, J C, Neill, J D

“…Gonadotropin releasing hormone is a hypothalamic decapeptide that stimulates the release of gonadotropic hormones from the anterior pituitary gland…”
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Potential Role for a Regulator of G Protein Signaling (RGS3) in Gonadotropin-Releasing Hormone (GnRH) Stimulated Desensitization by Neill, Jimmy D, Duck, L. Wayne, Sellers, Jeffrey C, Musgrove, Lois C, Scheschonka, Astrid, Druey, Kirk M, Kehrl, John H

“…The cellular and molecular mechanisms of gonadotrope desensitization are unknown but transduction of the GnRH signal is known to involve sequentially the GnRH…”
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Angiotensin II type-1 receptor subtype cDNAs: differential tissue expression and hormonal regulation by Kakar, S S, Sellers, J C, Devor, D C, Musgrove, L C, Neill, J D

“…A rat angiotensin, type 1A (AT1A) receptor cDNA was cloned recently and shown to be a member of the 7-transmembrane, G-protein coupled family of receptors…”
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Potential Regulatory Roles for G Protein-Coupled Receptor Kinases and β-Arrestins in Gonadotropin-Releasing Hormone Receptor Signaling by Neill, Jimmy D., Duck, L. Wayne, Musgrove, Lois C., Sellers, Jeffrey C.

“…Abstract GnRH stimulates gonadotropin secretion, which desensitizes unless the releasing hormone is secreted or administered in a pulsatile fashion. The…”
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High Efficiency Method for Gene Transfer in Normal Pituitary Gonadotropes: Adenoviral-Mediated Expression of G Protein-Coupled Receptor Kinase 2 Suppresses Luteinizing Hormone Secretion by Neill, Jimmy D., Musgrove, Lois C., Duck, L. Wayne, Sellers, Jeffrey C.

“…Abstract The level of LH secretion is determined by both alterations in gonadotrope responsiveness and alterations in GnRH secretion. The molecular mechanisms…”
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Rat gonadotropin-releasing hormone (GnRH) receptor: tissue expression and hormonal regulation of its mRNA by Kakar, S S, Grantham, K, Musgrove, L C, Devor, D, Sellers, J C, Neill, J D

“…The binding of gonadotropin-releasing hormone (GnRH) to its receptor in the anterior pituitary gland is the key molecular interaction regulating the…”
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A regulator of G protein signaling, RGS3, inhibits gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone (LH) secretion by Neill, J D, Duck, L W, Sellers, J C, Musgrove, L C, Kehrl, J H

“…Luteinizing hormone secreted by the anterior pituitary gland regulates gonadal function. Luteinizing hormone secretion is regulated both by alterations in…”
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Epitope-tagged gonadotropin-releasing hormone receptors heterologously-expressed in mammalian (COS-1) and insect (Sf9) cells by Neill, Jimmy D, Sellers, Jeffrey C, Musgrove, Lois C, Duck, L.Wayne

“…The molecular cloning and nucleotide sequencing of the gonadotropin-releasing hormone (GnRH) receptor represented an enhanced step in the experimental effort…”
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Newly recognized GnRH receptors: function and relative role by Neill, Jimmy D., Musgrove, Lois C., Duck, L. Wayne

“…Hypothalamic gonadotropin releasing hormone (GnRH I) and its pituitary receptor are responsible for the CNS regulation of reproduction. However, a second GnRH…”
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Newly recognized GnRH receptors: function and relative role by NEILL, Jimmy D, MUSGROVE, Lois C, DUCK, L. Wayne

“…Hypothalamic gonadotropin releasing hormone (GnRH I) and its pituitary receptor are responsible for the CNS regulation of reproduction. However, a second GnRH…”
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High Efficiency Method for Gene Transfer in Normal Pituitary Gonadotropes: Adenoviral-Mediated Expression of G Protein-Coupled Receptor Kinase 2 Suppresses Luteinizing Hormone Secretion1 by Neill, Jimmy D, Musgrove, Lois C, Duck, L. Wayne, Sellers, Jeffrey C

“…The level of LH secretion is determined by both alterations in gonadotrope responsiveness and alterations in GnRH secretion. The molecular mechanisms…”
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Potential Regulatory Roles for G Protein-Coupled Receptor Kinases and β-Arrestins in Gonadotropin-Releasing Hormone Receptor Signaling1 by Neill, Jimmy D, Duck, L. Wayne, Musgrove, Lois C, Sellers, Jeffrey C

“…GnRH stimulates gonadotropin secretion, which desensitizes unless the releasing hormone is secreted or administered in a pulsatile fashion. The mechanism of…”
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Epitope-tagged gonadotropin-releasing hormone receptors heterologously-expressed in mammalian (COS-1) and insect (Sf9) cells1Note: Supported by NIH Research Grant DK45519 to J.D.N.12Note: Presented as preliminary reports at the 1995 Endocrine Society Meetings (Washington, DC), and at the 1995 Society for Neuroscience Meetings (San Diego, CA).2 by Neill, Jimmy D, Sellers, Jeffrey C, Musgrove, Lois C, Duck, L.Wayne

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Identification by polymerase chain reaction of the G protein-coupled receptor kinases expressed in the mouse gonadotropic alpha T3-1 cell line by Neill, J D, Musgrove, L C, Sellers, J C, Duck, L W

“…G protein-coupled receptor kinases (GRK 1-6) stimulate short-term desensitization (< 5 min) by phosphorylating G-protein coupled receptors, and also…”
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Dual intracellular pathways in gonadotropin releasing hormone (GnRH) induced desensitization of luteinizing hormone (LH) secretion by Cassina, M.Patricia, Musgrove, Lois C., Duck, L.Wayne, Sellers, Jeffrey C., Neill, Jimmy D.

“…The mechanisms of GnRH-induced desensitization of LH secretion are poorly understood. Protein kinase C (PKC) and protein kinase A (PKA) desensitize some…”
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