Search Results - "Musgrove, A."

Biological determinants of endocrine resistance in breast cancer by Musgrove, Elizabeth A, Sutherland, Robert L

“…Key Points Endocrine therapies that target oestrogen action (anti-oestrogens and aromatase inhibitors) are widely used and successful breast cancer therapies,…”
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Anatomy of STEM teaching in North American universities by Stains, M, Harshman, J, Barker, M K, Chasteen, S V, Cole, R, DeChenne-Peters, S E, Eagan, Jr, M K, Esson, J M, Knight, J K, Laski, F A, Levis-Fitzgerald, M, Lee, C J, Lo, S M, McDonnell, L M, McKay, T A, Michelotti, N, Musgrove, A, Palmer, M S, Plank, K M, Rodela, T M, Sanders, E R, Schimpf, N G, Schulte, P M, Smith, M K, Stetzer, M, Van Valkenburgh, B, Vinson, E, Weir, L K, Wendel, P J, Wheeler, L B, Young, A M

“…Lecture is prominent, but practices vary A large body of evidence demonstrates that strategies that promote student interactions and cognitively engage…”
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Cyclins: Roles in mitogenic signaling and oncogenic transformation by Musgrove, Elizabeth A.

“…Cyclins are the regulatory subunits of kinases that control progress through the cell cycle. This review focuses on cyclins that are targets for extracellular…”
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Formal robotic training diminishes the learning curve for robotic pancreatoduodenectomy: Implications for new programs in complex robotic surgery by Schmidt, Carl R., Harris, Britney R., Musgrove, Kelsey A., Rao, Pavan, Marsh, J. Wallis, Thomay, Alan A., Hogg, Melissa E., Zeh, Herbert J., Zureikat, Amer H., Boone, Brian A.

“…Introduction The learning curve associated with robotic pancreatoduodenectomy (RPD) is a hurdle for new programs to achieve optimal results. Since early…”
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The prognostic and predictive value of serum CA19.9 in pancreatic cancer by Humphris, J.L., Chang, D.K., Johns, A.L., Scarlett, C.J., Pajic, M., Jones, M.D., Colvin, E.K., Nagrial, A., Chin, V.T., Chantrill, L.A., Samra, J.S., Gill, A.J., Kench, J.G., Merrett, N.D., Das, A., Musgrove, E.A., Sutherland, R.L., Biankin, A.V.

“…Current staging methods for pancreatic cancer (PC) are inadequate, and biomarkers to aid clinical decision making are lacking. Despite the availability of the…”
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Use of HSI to measure oxygen saturation in the lower limb and its correlation with healing of foot ulcers in diabetes by Jeffcoate, W. J., Clark, D. J., Savic, N., Rodmell, P. I., Hinchliffe, R. J., Musgrove, A., Game, F. L.

“…Aim To explore the use of hyperspectral imaging (HSI) to predict healing of diabetic foot ulcers in patients with diabetes. Methods We used a HSI technique…”
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Cytoplasmic Localization of β-Catenin is a Marker of Poor Outcome in Breast Cancer Patients by LOPEZ-KNOWLES, Elena, ZARDAWI, Sarah J, MCNEIL, Catriona M, MILLAR, Ewan K. A, CREA, Paul, MUSGROVE, Elizabeth A, SUTHERLAND, Robert L, O'TOOLE, Sandra A

“…β-catenin is involved in cell adhesion through catenin-cadherin complexes and as a transcriptional regulator in the Wnt signaling pathway. Its deregulation is…”
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Cell cycle control in breast cancer cells by Caldon, C. Elizabeth, Daly, Roger J., Sutherland, Robert L., Musgrove, Elizabeth A.

“…In breast cancer, cyclins D1 and E and the cyclin‐dependent kinase inhibitors p21 (Waf1/Cip1)and p27 (Kip1) are important in cell‐cycle control and as…”
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Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer by Caldon, C Elizabeth, Musgrove, Elizabeth A

“…The highly conserved E-type cyclins are core components of the cell cycle machinery, facilitating the transition into S phase through activation of the cyclin…”
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Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction by Scarlett, Christopher J, Colvin, Emily K, Pinese, Mark, Chang, David K, Morey, Adrienne L, Musgrove, Elizabeth A, Pajic, Marina, Apte, Minoti, Henshall, Susan M, Sutherland, Robert L, Kench, James G, Biankin, Andrew V

“…Chronic pancreatitis and pancreatic cancer are characterised by extensive stellate cell mediated fibrosis, and current therapeutic development includes…”
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Clinical and Pathologic Features of Familial Pancreatic Cancer by HUMPHRIS, Jeremy L, JOHNS, Amber L, SCOTT MEAD, R, GILL, Anthony J, SAMRA, Jaswinder S, KENCH, James G, MUSGROVE, Elizabeth A, TUCKER, Katherine M, SPIGELMAN, Allan D, WADDELL, Nic, GRIMMOND, Sean M, BIANKIN, Andrew V, SIMPSON, Skye H, COWLEY, Mark J, PAJIC, Marina, CHANG, David K, NAGRIAL, Adnan M, CHIN, Venessa T, CHANTRILL, Lorraine A, PINESE, Mark

“…Inherited predisposition to pancreatic cancer contributes significantly to its incidence and presents an opportunity for the development of early detection…”
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Downstream targets of growth factor and oestrogen signalling and endocrine resistance: the potential roles of c-Myc, cyclin D1 and cyclin E by Butt, Alison J, McNeil, Catriona M, Musgrove, Elizabeth A, Sutherland, Robert L

“…Antioestrogen therapy is a highly effective treatment for patients with oestrogen-receptor (ER)-positive breast cancer, emphasising the central role of…”
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Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer by Stone, Andrew, Valdés-Mora, Fatima, Gee, Julia M W, Farrow, Lynne, McClelland, Richard A, Fiegl, Heidi, Dutkowski, Carol, McCloy, Rachael A, Sutherland, Robert L, Musgrove, Elizabeth A, Nicholson, Robert I

“…In the present study, we have taken the novel approach of using an in vitro model representative of tamoxifen-withdrawal subsequent to clinical relapse to…”
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Clinical and molecular characterization of HER2 amplified-pancreatic cancer by Chou, Angela, Waddell, Nicola, Cowley, Mark J, Gill, Anthony J, Chang, David K, Patch, Ann-Marie, Nones, Katia, Wu, Jianmin, Pinese, Mark, Johns, Amber L, Miller, David K, Kassahn, Karin S, Nagrial, Adnan M, Wasan, Harpreet, Goldstein, David, Toon, Christopher W, Chin, Venessa, Chantrill, Lorraine, Humphris, Jeremy, Mead, R Scott, Rooman, Ilse, Samra, Jaswinder S, Pajic, Marina, Musgrove, Elizabeth A, Pearson, John V, Morey, Adrienne L, Grimmond, Sean M, Biankin, Andrew V

“…Pancreatic cancer is one of the most lethal and molecularly diverse malignancies. Repurposing of therapeutics that target specific molecular mechanisms in…”
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Estrogen and antiestrogen regulation of cell cycle progression in breast cancer cells by Doisneau-Sixou, S F, Sergio, C M, Carroll, J S, Hui, R, Musgrove, E A, Sutherland, R L

“…The central involvement of estrogen in the development of the mammary gland and in the genesis of breast cancer has lent impetus to studies of the links…”
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Meta-analysis and gene set enrichment relative to er status reveal elevated activity of MYC and E2F in the "basal" breast cancer subgroup by Alles, M Chehani, Gardiner-Garden, Margaret, Nott, David J, Wang, Yixin, Foekens, John A, Sutherland, Robert L, Musgrove, Elizabeth A, Ormandy, Christopher J

“…Breast cancers lacking the estrogen receptor (ER) can be distinguished from other breast cancers on the basis of poor prognosis, high grade, distinctive…”
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Cyclin D1, EMS1 and 11q13 amplification in breast cancer by Ormandy, Christopher J, Musgrove, Elizabeth A, Hui, Rina, Daly, Roger J, Sutherland, Robert L

“…Chromosome locus 11q13 is frequently amplified in a number of human cancers including carcinoma of the breast where up to 15% carry this chromosomal…”
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Evaluation of the effect of nurse education on patient-reported foot checks and foot care behaviour of people with diabetes receiving haemodialysis by Brand, S. L., Musgrove, A., Jeffcoate, W. J., Lincoln, N. B.

“…Aims To assess whether a programme of nurse education increased the frequency with which nurses conducted foot checks on people with diabetes undergoing…”
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Estrogen Regulation of Cyclin E2 Requires Cyclin D1 but Not c-Myc by Caldon, C. Elizabeth, Sergio, C. Marcelo, Schütte, Judith, Boersma, Marijke N., Sutherland, Robert L., Carroll, Jason S., Musgrove, Elizabeth A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Differences in degradation lead to asynchronous expression of cyclin E1 and cyclin E2 in cancer cells by Caldon, C. Elizabeth, Sergio, C. Marcelo, Sutherland, Robert L., Musgrove, Elizabeth A.

“…Cyclin E1 is expressed at the G₁/S phase transition of the cell cycle to drive the initiation of DNA replication and is degraded during S/G₂M. Deregulation of…”
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