Search Results - "Muselík, Jan"

A Critical Overview of FDA and EMA Statistical Methods to Compare In Vitro Drug Dissolution Profiles of Pharmaceutical Products by Muselík, Jan, Komersová, Alena, Kubová, Kateřina, Matzick, Kevin, Skalická, Barbora

“…A drug dissolution profile is one of the most critical dosage form characteristics with immediate and controlled drug release. Comparing the dissolution…”
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Bilayer mucoadhesive buccal films with prolonged release of ciclopirox olamine for the treatment of oral candidiasis: In vitro development, ex vivo permeation testing, pharmacokinetic and efficacy study in rabbits by Gajdošová, Markéta, Vetchý, David, Muselík, Jan, Gajdziok, Jan, Juřica, Jan, Vetchá, Martina, Hauptman, Karel, Jekl, Vladimír

“…[Display omitted] The incidence of fungal infections has increased in recent decades not only in patients with predisposing and risk factors, but it has also…”
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Development of Orodispersible Films Containing Benzydamine Hydrochloride Using a Modified Solvent Casting Method by Pechová, Veronika, Gajdziok, Jan, Muselík, Jan, Vetchý, David

“…The aim of this study was to develop benzydamine hydrochloride-loaded orodispersible films using the modification of a solvent casting method. An innovative…”
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Structure, dynamics, and functional properties of hybrid alginate-pectin gels dually crosslinked by Ca2+ and Zn2+ ions designed as a delivery device for self-emulsifying systems for lipophilic phytotherapeutics by Urbanova, Martina, Macku, Jan, Kubova, Katerina, Vyslouzil, Jakub, Muselík, Jan, Slouf, Miroslav, Sedenkova, Ivana, Kockova, Olga, Janisova, Larisa, Masek, Josef, Maskova, Eliska, Novobilsky, Adam, Parenicova, Martina, Konefal, Rafal, Czernek, Jiri, Vetchy, David, Pavelkova, Miroslava, Brus, Jiri

“…Alginate gels are outstanding biomaterials widely applicable in food and pharmaceutical industries. This contribution provides comprehensive insight into the…”
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Factor analysis in optimization of formulation of high content uniformity tablets containing low dose active substance by Lukášová, Ivana, Muselík, Jan, Franc, Aleš, Goněc, Roman, Mika, Filip, Vetchý, David

“…Warfarin is intensively discussed drug with narrow therapeutic range. There have been cases of bleeding attributed to varying content or altered quality of the…”
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Preparation of pellets with controlled release of glucose as prevention of hypoglycaemia in paediatric patients by Franc, Aleš, Muselík, Jan, Sabadková, Dana, Neumann, David

“…[Display omitted] Hypoglycaemic episodes represent serious and frequent complications of type 1 and 2 diabetes. Theoretically, the risk of hypoglycaemic states…”
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Influence of Process Parameters on Content Uniformity of a Low Dose Active Pharmaceutical Ingredient in a Tablet Formulation According to GMP by Muselík, Jan, Franc, Aleš, Doležel, Petr, Goněc, Roman, Krondlová, Anna, Lukášová, Ivana

“…The article describes the development and production of tablets using direct compression of powder mixtures. The aim was to describe the impact of filler…”
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The effects of the treatment conditions on the dissolution profile of ethylcellulose coated pellets by Pavloková, Sylvie, Muselík, Jan, Sabadková, Dana, Bernatová, Silvie, Samek, Ota, Neumann, David, Franc, Aleš

“…Due to the additional particle coalescence in the coating, changes in the dissolution profile occur over time in the formulations coated by aqueous…”
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Efficacy of poly (lactic-co-glycolic acid) microparticles as a gonadotropin-releasing hormone analogue delivery system to stimulate ovulation of peled Coregonus peled by Knowles, Jindřiška, Vysloužil, Jakub, Muselík, Jan, Stejskal, Vlastimil, Kouřil, Jan, Podhorec, Peter

“…The aim of the study was to determine the efficacy of poly (lactic-co-glycolic acid) microparticles as a carrier of gonadotropin-releasing hormone analogues…”
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The Chemical Composition of Achillea wilhelmsii C. Koch and Its Desirable Effects on Hyperglycemia, Inflammatory Mediators and Hypercholesterolemia as Risk Factors for Cardiometabolic Disease by Khazneh, Elian, Hřibová, Petra, Hošek, Jan, Suchý, Pavel, Kollár, Peter, Pražanová, Gabriela, Muselík, Jan, Hanaková, Zuzana, Václavík, Jiří, Miłek, Michał, Legáth, Jaroslav, Šmejkal, Karel

“…This study was done to identify the content compounds of Achillea wilhelmsii (A. wilhelmsii) and to evaluate its hypoglycemic and anti-hypercholesterolemic…”
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Exploration of Neusilin ® US2 as an Acceptable Filler in HPMC Matrix Systems-Comparison of Pharmacopoeial and Dynamic Biorelevant Dissolution Study by Bílik, Tomáš, Vysloužil, Jakub, Naiserová, Martina, Muselík, Jan, Pavelková, Miroslava, Mašek, Josef, Čopová, Drahomíra, Čulen, Martin, Kubová, Kateřina

“…Modern pharmaceutical technology still seeks new excipients and investigates the further use in already known ones. An example is magnesium aluminometasilicate…”
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Synthesis, structural characterization, antiradical and antidiabetic activities of copper(II) and zinc(II) Schiff base complexes derived from salicylaldehyde and β-alanine by Vančo, Ján, Marek, Jaromír, Trávníček, Zdeněk, Račanská, Eva, Muselík, Jan, Švajlenová, Ol’ga

“…A series of copper(II) and zinc(II) complexes involving a tridentate O,N,O’-donor Schiff base derived from salicylaldehyde and β-alanine {i.e…”
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Evaluation and Comparison of Three Types of Spray Dried Coprocessed Excipient Avicel® for Direct Compression by Solný, Tomaš, Muselík, Jan, Elbl, Jan, Franc, Ales, Svačinová, Petra, Vraníková, Barbora, Vodáčková, Pavlína, Kubalák, Roman

“…As coprocessed excipients (CPE) gain a lot of focus recently, this article compares three commercially available CPE of Avicel brand, namely, CE 15, DG, and…”
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Influence of concentration and type of microcrystalline cellulose on the physical properties of tablets containing Cornelian cherry fruits by Franc, Aleš, Kurhajec, Slavomir, Pavloková, Sylvie, Sabadková, Dana, Muselík, Jan

“…The aim of this study was to find the optimal tablet composition with maximum content of dried fruits (Cornus mas L.). The effect of three different…”
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The effect of amorphous and crystal sodium warfarin and its content uniformity on bioequivalence of tablets by Franc, Aleš, Muselík, Jan, Zeman, Jiří, Lukášová, Ivana, Kurhajec, Slavomír, Bartoníčková, Eva, Galvánková, Lucie, Mika, Filip, Dominik, Martin, Vetchý, David

“…Warfarin is intensively discussed in terms of generic substitution due to particular cases of bleeding, which are attributable to fluctuations in API content…”
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Structural Changes of Sodium Warfarin in Tablets Affecting the Dissolution Profiles and Potential Safety of Generic Substitution by Muselík, Jan, Urbanova, Martina, Bartoníčková, Eva, Palovčík, Jakub, Vetchý, David, Czernek, Jiří, Janisova, Larisa, Velychkivska, Nadiia, Franc, Aleš, Brus, Jiří

“…At present, the risk of generic substitutions in warfarin tablets is still being discussed. The aim of this study was to assess whether API interactions with…”
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Measurement of Antioxidant Activity of Wine Catechins, Procyanidins, Anthocyanins and Pyranoanthocyanins by Muselík, Jan, García-Alonso, María, Martín-López, María P., Žemlička, Milan, Rivas-Gonzalo, Julián C.

“…Nowadays, there is considerable interest in finding out about antioxidants thatare consumed in the habitual diet. It is known that polyphenols are involved in…”
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Coated pellets with delayed-release glucose for prevention of hypoglycemic episodes by Sabadková, Dana, Franc, Aleš, Muselík, Jan, Neumann, David

“…Patients tend to prevent hypoglycemia by excessive saccharide intake leading to poorer glycemic control with potentially fatal consequences. This problem could…”
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The Effect of Acid pH Modifiers on the Release Characteristics of Weakly Basic Drug from Hydrophlilic–Lipophilic Matrices by Dvořáčková, Kateřina, Doležel, Petr, Mašková, Eliška, Muselík, Jan, Kejdušová, Martina, Vetchý, David

“…The solubility of weakly basic drugs within passage though GI tract leads to pH-dependent or even incomplete release of these drugs from extended release…”
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Antiradical and cytoprotective activities of several C-geranyl-substituted flavanones from Paulownia tomentosa fruit by Zima, Ales, Hosek, Jan, Treml, Jakub, Muselík, Jan, Suchý, Pavel, Prazanová, Gabriela, Lopes, Ana, Zemlicka, Milan

“…Antiradical and cytoprotective activities of several flavanones isolated from Paulownia tomentosa (Thunb.) Steud. (Scrophulariaceae) have been evaluated using…”
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