Search Results - "Musci, Thomas"

Cell-free DNA Analysis for Noninvasive Examination of Trisomy by Norton, Mary E, Jacobsson, Bo, Swamy, Geeta K, Laurent, Louise C, Ranzini, Angela C, Brar, Herb, Tomlinson, Mark W, Pereira, Leonardo, Spitz, Jean L, Hollemon, Desiree, Cuckle, Howard, Musci, Thomas J, Wapner, Ronald J

“…This multicenter study compared a prenatal assay of cell-free DNA with a standard method of screening for trisomies among women at average risk. The positive…”
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Gestational age and maternal weight effects on fetal cell-free DNA in maternal plasma by Wang, Eric, Batey, Annette, Struble, Craig, Musci, Thomas, Song, Ken, Oliphant, Arnold

“…ABSTRACT Objective To determine the effects of gestational age and maternal weight on percent fetal cell‐free DNA (cfDNA) in maternal plasma and the change in…”
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Clinical performance of non-invasive prenatal testing (NIPT) using targeted cell-free DNA analysis in maternal plasma with microarrays or next generation sequencing (NGS) is consistent across multiple controlled clinical studies by Stokowski, Renee, Wang, Eric, White, Karen, Batey, Annette, Jacobsson, Bo, Brar, Herb, Balanarasimha, Madhumitha, Hollemon, Desiree, Sparks, Andrew, Nicolaides, Kypros, Musci, Thomas J.

“…Objective To evaluate the clinical performance of non‐invasive prenatal testing for trisomy 21, 18, and 13 using targeted cell‐free DNA (cfDNA) analysis…”
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Clinical utility and cost of non-invasive prenatal testing with cfDNA analysis in high-risk women based on a US population by Song, Ken, Musci, Thomas J., Caughey, Aaron B.

“…Abstract Objective: Evaluate the clinical and economic consequences of fetal trisomy 21 (T21) screening with non-invasive prenatal testing (NIPT) in high-risk…”
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Clinical experience of noninvasive prenatal testing with cell-free DNA for fetal trisomies 21, 18, and 13, in a general screening population by Fairbrother, Genevieve, Johnson, Shayla, Musci, Thomas J., Song, Ken

“…ABSTRACT Objective Evaluate noninvasive prenatal testing (NIPT) with cell‐free DNA as a screening method for trisomies 21, 18, and 13 in an obstetrical…”
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Assessment of fetal sex chromosome aneuploidy using directed cell-free DNA analysis by Nicolaides, Kypros H, Musci, Thomas J, Struble, Craig A, Syngelaki, Argyro, Gil, M M

“…To examine the performance of chromosome-selective sequencing of cell-free (cf) DNA in maternal blood for assessment of fetal sex chromosome aneuploidies. This…”
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Non-invasive prenatal testing with cell-free DNA: US physician attitudes toward implementation in clinical practice by Musci, Thomas J., Fairbrother, Genevieve, Batey, Annette, Bruursema, Jennifer, Struble, Craig, Song, Ken

“…ABSTRACT Objective The aim of this study was to assess awareness, potential adoption, and current utilization of non‐invasive prenatal testing (NIPT) analysis…”
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Isolation of single circulating trophoblasts from maternal circulation for noninvasive fetal copy number variant profiling by Doffini, Anna, Forcato, Claudio, Mangano, Chiara, Lattuada, Debora, Aversa, Roberta, Maranta, Chiara, Giovannone, Emilia D., Buson, Genny, Bolognesi, Chiara, Maiocchi, Rebecca, Dori, Martina, Jamal, Liyana, Ahmad, Raidah B., Yeo, George S. H., Yeo, Tai Wai, Saragozza, Silvia, Silipigni, Rosamaria, Serafini, Marta, Biondi, Andrea, Perego, Sofia, Vergani, Patrizia, Ferrazzi, Enrico, Ricciardi‐Castagnoli, Paola, Musci, Thomas J., Grati, Francesca Romana

“…Objective To develop a multi‐step workflow for the isolation of circulating extravillous trophoblasts (cEVTs) by describing the key steps enabling a…”
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Complications of Term Pregnancies Beyond 37 Weeks of Gestation by Caughey, Aaron B., Musci, Thomas J.

“…OBJECTIVE:To estimate when rates of pregnancy complications increase beyond 37 weeks of gestation. METHODS:We designed a retrospective, cohort study of all…”
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COSMOS: a platform for real-time morphology-based, label-free cell sorting using deep learning by Salek, Mahyar, Li, Nianzhen, Chou, Hou-Pu, Saini, Kiran, Jovic, Andreja, Jacobs, Kevin B., Johnson, Chassidy, Lu, Vivian, Lee, Esther J., Chang, Christina, Nguyen, Phuc, Mei, Jeanette, Pant, Krishna P., Wong-Thai, Amy Y., Smith, Quillan F., Huang, Stephanie, Chow, Ryan, Cruz, Janifer, Walker, Jeff, Chan, Bryan, Musci, Thomas J., Ashley, Euan A., Masaeli, Maddison (Mahdokht)

“…Cells are the singular building blocks of life, and a comprehensive understanding of morphology, among other properties, is crucial to the assessment of…”
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The fetal fraction of cell-free DNA in maternal plasma is not affected by a priori risk of fetal trisomy by Brar, Herb, Wang, Eric, Struble, Craig, Musci, Thomas J., Norton, Mary E.

“…Objective: To determine the relationship between a priori risk for fetal trisomy and the fraction of fetal cell-free DNA (cfDNA) in maternal blood. Methods: A…”
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The cost-effectiveness of prenatal screening for spinal muscular atrophy by Little, Sarah E., MD, Janakiraman, Vanitha, MD, Kaimal, Anjali, MD, MAS, Musci, Thomas, MD, Ecker, Jeffrey, MD, Caughey, Aaron B., MD, PhD

“…Objective We sought to investigate the cost-effectiveness of prenatal screening for spinal muscular atrophy (SMA). Study Design A decision analytic model was…”
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Author Correction: COSMOS: a platform for real-time morphology-based, label-free cell sorting using deep learning by Salek, Mahyar, Li, Nianzhen, Chou, Hou-Pu, Saini, Kiran, Jovic, Andreja, Jacobs, Kevin B., Johnson, Chassidy, Lu, Vivian, Lee, Esther J., Chang, Christina, Nguyen, Phuc, Mei, Jeanette, Pant, Krishna P., Wong-Thai, Amy Y., Smith, Quillan F., Huang, Stephanie, Chow, Ryan, Cruz, Janifer, Walker, Jeff, Chan, Bryan, Musci, Thomas J., Ashley, Euan A., Masaeli, Maddison (Mahdokht)

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P616: Cell-based noninvasive prenatal screening for a comprehensive fetal genome profiling for pathogenic submicroscopic CNVs in circulating trophoblasts from maternal blood by Doffini, Anna, Forcato, Claudio, Mangano, Chiara, Lattuada, Debora, Aversa, Roberta, Maranta, Chiara, Giovannone, Emilia, Buson, Genny, Bolognesi, Chiara, Maiocchi, Rebecca, Dori, Martina, Jamal, Liyana, Ahmad, Raidah, Yeo, George S.H., Yeo, Tai Wai, Saragozza, Silvia, Silipigni, Rosamaria, Serafini, Marta, Biondi, Andrea, Perego, Sofia, Vergani, Patrizia, Ferrazzi, Enrico, Ricciardi-Castagnoli, Paola, Musci, Thomas, Grati, Francesca Romana

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The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function by Zhang, Ying, Musci, Thomas, Derynck, Rik

“…Background: The invertebrate and vertebrate Smad proteins have recently been identified as important mediators of the responses to transforming growth factor β…”
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Cost-effectiveness analysis of prenatal population-based fragile X carrier screening by Musci, Thomas J., Caughey, Aaron B.

“…To investigate the cost-effectiveness of a widespread prenatal population-based fragile X carrier screening program. A decision tree was designed comparing…”
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Prenatal Carrier Testing for Fragile X: Counseling Issues and Challenges by Musci, Thomas J., MD, Moyer, Krista, MGC

“…Healthy women who carry a ‘‘premutation'’ in the FMR1 gene (or fragile X mental retardation protein) can pass on a further mutated copy of FMR1 to either male…”
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Cell-Free DNA Analysis for Noninvasive Examination of Trisomy by Norton, Mary E, Jacobsson, Bo, Swamy, Geeta K, Laurent, Louise C, Ranzini, Angela C, Brar, Herb, Tomlinson, Mark W, Pereira, Leonardo, Spitz, Jean L, Hollemon, Desiree, Cuckle, Howard, Musci, Thomas J, Wapner, Ronald J

“…ABSTRACTWhile cell-free DNA (cfDNA) testing for fetal aneuploidy has been shown to have a high detection rate for trisomy, most large studies have included…”
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Assessment of Fetal Sex Chromosome Aneuploidy Using Directed Cell-Free DNA Analysis by Nicolaides, Kypros H, Musci, Thomas J, Struble, Craig A, Syngelaki, Argyro, del Mar Gil, Maria

“…ABSTRACTPrenatal screening for fetal aneuploidies has focused on trisomies 21, 18, and 13. The sex chromosome aneuploidies, monosomy X (45,X), Klinefelter…”
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Fast MR Imaging of Fetal CNS Anomalies in Utero by Simon, Erin M, Goldstein, Ruth B, Coakley, Fergus V, Filly, Roy A, Broderick, Kelly C, Musci, Thomas J, Barkovich, A. James

“…Although sonography is the primary imaging technique for evaluating the developing fetus, significant limitations exist in the sonographic prenatal diagnosis…”
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