Search Results - "Muschler, G F"

Bone graft materials. An overview of the basic science by Bauer, T W, Muschler, G F

“…Autograft, allograft, and synthetic bone graft substitute materials play an important role in reconstructive orthopaedic surgery, and understanding the…”
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Evaluation of rhBMP-2/collagen/TCP-HA bone graft with and without bone marrow cells in the canine femoral multi defect model by Luangphakdy, V, Shinohara, K, Pan, H, Boehm, C, Samaranska, A, Muschler, G F

“…Recombinant human bone morphogenetic protein-2, when applied to an absorbable type 1 bovine collagen sponge (rhBMP-2/ACS) is an effective therapy in many bone…”
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Aspiration to Obtain Osteoblast Progenitor Cells from Human Bone Marrow: The Influence of Aspiration Volume by MUSCHLER, GEORGE F, BOEHM, CYNTHIA, EASLEY, KIRK

“…Bone marrow contains osteoblast progenitor cells that can be obtained with aspiration and appear to arise from a population of pluripotential connective-tissue…”
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Classification systems for platelet-rich plasma by Rossi, L A, Murray, I R, Chu, C R, Muschler, G F, Rodeo, S A, Piuzzi, N S

“…There is good scientific rationale to support the use of growth factors to promote musculoskeletal tissue regeneration. However, the clinical effectiveness of…”
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Characterization of human bone marrow stromal cells with respect to osteoblastic differentiation by Majors, A K, Boehm, C A, Nitto, H, Midura, R J, Muschler, G F

“…Human bone marrow was harvested by means of iliac crest aspiration and cultured under conditions that promote an osteoblastic phenotype. Human bone marrow…”
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Primary Cells Isolated from Human Knee Cartilage Reveal Decreased Prevalence of Progenitor Cells but Comparable Biological Potential During Osteoarthritic Disease Progression by Mantripragada, V.P., Bova, W.A., Boehm, C., Piuzzi, N.S., Obuchowski, N.A., Midura, R.J., Muschler, G.F.

“…Current decisions on cellular therapies for osteoarthritis are based primarily on clinical experience or on assumptions about preferred cell sourcing. They…”
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Prosthetic Knee Replacement after Resection of a Malignant Tumor of the Distal Part of the Femur. Medium to Long-Term Results by KAWAI, AKIRA, MUSCHLER, GEORGE F, LANE, JOSEPH M, OTIS, JAMES C, HEALEY, JOHN H

“…We evaluated the medium to long-term results of treatment with a custom prosthetic knee replacement after wide resection of a primary malignant tumor of the…”
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Evaluation of human bone morphogenetic protein 2 in a canine spinal fusion model by Muschler, G F, Hyodo, A, Manning, T, Kambic, H, Easley, K

“…The efficacy of purified recombinant human bone morphogenetic protein-2 (rhBMP-2) delivered in a porous biodegradable copolymer, poly [D,L…”
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Comparative Assessment of Primary Osteoarthritis Progression Using Conventional Histopathology, Polarized Light Microscopy, and Immunohistochemistry by Mantripragada, V.P., Gao, W., Piuzzi, N.S., Hoemann, C.D., Muschler, G.F., Midura, R.J.

“…Objective Evaluation of collagen orientation and arrangement in articular cartilage can improve our understanding of primary osteoarthritis (OA) progression…”
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Histopathological assessment of primary osteoarthritic knees in large patient cohort reveal the possibility of several potential patterns of osteoarthritis initiation by Mantripragada, V.P., Piuzzi, N.S., Zachos, T., Obuchowski, N.A., Muschler, G.F., Midura, R.J.

“…The two main objectives of the study include (1) Test the hypothesis that the lateral femoral condyle (LFC) in patients with primary OA and varus knees…”
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Evaluation of collagen ceramic composite graft materials in a spinal fusion model by Muschler, G F, Negami, S, Hyodo, A, Gaisser, D, Easley, K, Kambic, H

“…Autogenous bone graft is highly effective in inducing a bone healing response in most clinical settings. However, significant morbidity can occur related to…”
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Age- and gender-related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors by Muschler, George F, Nitto, Hironori, Boehm, Cynthia A, Easley, Kirk A

“…Bone marrow harvested by aspiration contains connective tissue progenitor cells which can be induced to express a bone phenotype in vitro. The number of…”
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Evaluation of bone-grafting materials in a new canine segmental spinal fusion model by Muschler, G F, Huber, B, Ullman, T, Barth, R, Easley, K, Otis, J O, Lane, J M

“…This paper describes a new canine segmental spinal fusion model for the comparison of bone-grafting materials. The test sites in the model are three separate…”
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Candida (Torulopsis) glabrata Septic Arthritis by Gumbo, Tawanda, Isada, Carlos M., Muschler, George F., Longworth, David L.

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A custom distal femoral prosthesis for reconstruction of large defects following wide excision for sarcoma: results and prognostic factors by Muschler, G F, Ihara, K, Lane, J M, Healey, J H, Levine, M J, Otis, J C, Burstein, A H

“…Between 1979 and 1986, 37 patients with sarcoma of the distal femur underwent limb salvage using a custom prosthetic knee replacement. Thirteen (35%) had early…”
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Practical Modeling Concepts for Connective Tissue Stem Cell and Progenitor Compartment Kinetics by Muschler, George F., Midura, Ronald J., Nakamoto, Chizu

“…Stem cell activation and development is central to skeletal development, maintenance, and repair, as it is for all tissues. However, an integrated model of…”
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Factors Affecting Connective Tissue Progenitors and Orthopaedic Implications by Hung, C., Nakamoto, C., Muschler, G. F.

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The design and use of animal models for translational research in bone tissue engineering and regenerative medicine by Muschler, George F, Raut, Vivek P, Patterson, Thomas E, Wenke, Joseph C, Hollinger, Jeffrey O

“…This review provides an overview of animal models for the evaluation, comparison, and systematic optimization of tissue engineering and regenerative medicine…”
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A three-dimensional scaffold with precise micro-architecture and surface micro-textures by Mata, Alvaro, Kim, Eun Jung, Boehm, Cynthia A, Fleischman, Aaron J, Muschler, George F, Roy, Shuvo

“…Abstract A three-dimensional (3D) structure comprising precisely defined micro-architecture and surface micro-textures, designed to present specific physical…”
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In vivo transplantation of autogenous marrow-derived cells following rapid intraoperative magnetic separation based on hyaluronan to augment bone regeneration by Caralla, Tonya, Joshi, Powrnima, Fleury, Sean, Luangphakdy, Viviane, Shinohara, Kentaro, Pan, Hui, Boehm, Cynthia, Vasanji, Amit, Hefferan, Theresa E, Walker, Esteban, Yaszemski, Michael, Hascall, Vincent, Zborowski, Maciej, Muschler, George F

“…This project was designed to test the hypothesis that rapid intraoperative processing of bone marrow based on hyaluronan (HA) could be used to improve the…”
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