Search Results - "Muscat Galea, Charlene"
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Method optimization for drug impurity profiling in supercritical fluid chromatography: Application to a pharmaceutical mixture
Published in Journal of Chromatography A (01-12-2017)“…•Effect of different modifier and injection solvent compositions on retention and peak shape.•Optimization of temperature, back-pressure and gradient time with…”
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Investigation of the effect of column temperature and back-pressure in achiral supercritical fluid chromatography within the context of drug impurity profiling
Published in Journal of Chromatography A (06-10-2017)“…•Characterization of a set of polar and aromatic stationary phases.•Optimization of temperature and back-pressure with a response surface design…”
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Investigation of the effect of mobile phase composition on selectivity using a solvent-triangle based approach in achiral SFC
Published in Journal of pharmaceutical and biomedical analysis (05-01-2017)“…•A solvent-triangle based approach in SFC.•Effect of modifier composition on selectivity.•Optimization of mobile phase composition in achiral SFC. Defining a…”
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First inter-laboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities
Published in Journal of pharmaceutical and biomedical analysis (30-11-2018)“…[Display omitted] •Inter-laboratory study was conducted for the first time in SFC.•This study involved 19 participating laboratories from 4 continents and 9…”
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