Search Results - "Muscat, Samantha N"
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Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis
Published in eLife (22-01-2021)“…Despite the requirement for -lineage (Scx ) cells during tendon development, the function of Scx cells during adult tendon repair, post-natal growth, and adult…”
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Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing
Published in Matrix biology (01-01-2024)“…•Periostin-lineage cells contribute to a transient but not persistent myofibroblast population.•Periostin serves as a supportive niche for myofibroblast…”
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Metabolic Regulation of Tendon Inflammation and Healing Following Injury
Published in Current rheumatology reports (10-02-2021)“…Purpose of Review This review seeks to provide an overview of the role of inflammation and metabolism in tendon cell function, tendinopathy, and tendon…”
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Impact of isolation method on cellular activation and presence of specific tendon cell subpopulations during in vitro culture
Published in The FASEB journal (01-07-2021)“…Tendon injuries are common and heal poorly, due in part to a lack of understanding of fundamental tendon cell biology. A major impediment to the study of…”
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Defining the spatial-molecular map of fibrotic tendon healing and the drivers of Scleraxis-lineage cell fate and function
Published in Cell reports (Cambridge) (22-11-2022)“…Tendon injuries heal via a scar-mediated response, and there are no biological approaches to promote more regenerative healing. Mouse flexor tendons heal…”
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