Search Results - "Muscat, Samantha N"

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  1. 1

    Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis by Best, Katherine T, Korcari, Antonion, Mora, Keshia E, Nichols, Anne Ec, Muscat, Samantha N, Knapp, Emma, Buckley, Mark R, Loiselle, Alayna E

    Published in eLife (22-01-2021)
    “…Despite the requirement for -lineage (Scx ) cells during tendon development, the function of Scx cells during adult tendon repair, post-natal growth, and adult…”
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    Journal Article
  2. 2

    Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing by Ackerman, Jessica E., Muscat, Samantha N., Adjei-Sowah, Emmanuela, Korcari, Antonion, Nichols, Anne E.C., Buckley, Mark R., Loiselle, Alayna E.

    Published in Matrix biology (01-01-2024)
    “…•Periostin-lineage cells contribute to a transient but not persistent myofibroblast population.•Periostin serves as a supportive niche for myofibroblast…”
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    Journal Article
  3. 3

    Metabolic Regulation of Tendon Inflammation and Healing Following Injury by Ackerman, Jessica E., Best, Katherine T., Muscat, Samantha N., Loiselle, Alayna E.

    Published in Current rheumatology reports (10-02-2021)
    “…Purpose of Review This review seeks to provide an overview of the role of inflammation and metabolism in tendon cell function, tendinopathy, and tendon…”
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    Journal Article
  4. 4

    Impact of isolation method on cellular activation and presence of specific tendon cell subpopulations during in vitro culture by Nichols, Anne E. C., Muscat, Samantha N., Miller, Sarah E., Green, Luke J., Richards, Michael S., Loiselle, Alayna E.

    Published in The FASEB journal (01-07-2021)
    “…Tendon injuries are common and heal poorly, due in part to a lack of understanding of fundamental tendon cell biology. A major impediment to the study of…”
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  5. 5

    Defining the spatial-molecular map of fibrotic tendon healing and the drivers of Scleraxis-lineage cell fate and function by Ackerman, Jessica E, Best, Katherine T, Muscat, Samantha N, Pritchett, Elizabeth M, Nichols, Anne E C, Wu, Chia-Lung, Loiselle, Alayna E

    Published in Cell reports (Cambridge) (22-11-2022)
    “…Tendon injuries heal via a scar-mediated response, and there are no biological approaches to promote more regenerative healing. Mouse flexor tendons heal…”
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    Journal Article