Search Results - "Mus, M"
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A new species of Cloudina from the terminal Ediacaran of Spain
Published in Precambrian research (2010)“…The terminal Ediacaran genus Cloudina includes some of the earliest biomineralized fossils. It consists of a tube formed by stacked funnel-shaped elements, and…”
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Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin‐17A production
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-01-2011)“…Objective Both Th1 cells and Th17 cells have been recognized in rheumatoid arthritis (RA); however, it remains unclear whether Th1 cells and/or Th17 cells are…”
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Vehicle development, pharmacokinetics and toxicity of the anti-invasive agent 4-fluoro-3',4',5'-trimethoxychalcone in rodents
Published in PloS one (22-02-2018)“…Effective inhibitors of invasion and metastasis represent a serious unmet clinical need. We have recently identified 4-fluoro-3',4',5'-trimethoxychalcone or…”
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4
Blood-derived dendritic cell vaccinations induce immune responses that correlate with clinical outcome in patients with chemo-naive castration-resistant prostate cancer
Published in Journal for immunotherapy of cancer (14-11-2019)“…BackgroundClinical benefit of cellular immunotherapy has been shown in patients with castration-resistant prostate cancer (CRPC). We investigated the…”
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NBAtlas: A harmonized single-cell transcriptomic reference atlas of human neuroblastoma tumors
Published in Cell reports (Cambridge) (22-10-2024)“…Neuroblastoma, a rare embryonic tumor arising from neural crest development, is responsible for 15% of pediatric cancer-related deaths. Recently, several…”
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IL-23 receptor deficiency results in lower bone mass via indirect regulation of bone formation
Published in Scientific reports (13-05-2021)“…The IL-23 receptor (IL-23R) signaling pathway has pleiotropic effects on the differentiation of osteoclasts and osteoblasts, since it can inhibit or stimulate…”
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Lack of IL-17 Receptor A signaling aggravates lymphoproliferation in C57BL/6 lpr mice
Published in Scientific reports (11-03-2019)“…Defects in Fas function correlate with susceptibility to systemic autoimmune diseases like autoimmune lymphoproliferative syndrome (ALPS) and systemic lupus…”
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MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells
Published in Scientific reports (14-07-2021)“…MYCN is an oncogenic driver in neural crest-derived neuroblastoma and medulloblastoma. To better understand the early effects of MYCN activation in a…”
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Diagnosis of pediatric central nervous system tumors using methylation profiling of cfDNA from cerebrospinal fluid
Published in Clinical epigenetics (05-07-2024)“…Pediatric central nervous system tumors remain challenging to diagnose. Imaging approaches do not provide sufficient detail to discriminate between different…”
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The current level of shared decision-making in anesthesiology: an exploratory study
Published in BMC anesthesiology (12-07-2017)“…Shared decision-making (SDM) seeks to involve both patients and clinicians in decision-making about possible health management strategies, using patients'…”
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The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness
Published in Scientific reports (14-01-2020)“…Neuroblastoma is an aggressive childhood cancer arising from sympatho-adrenergic neuronal progenitors. The low survival rates for high-risk disease point to an…”
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12
Using computer-aided detection in mammography as a decision support
Published in European radiology (01-10-2010)“…Objective: To evaluate an interactive computer-aided detection (CAD) system for reading mammograms to improve decision making. Methods: A dedicated…”
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IL-23 dependent and independent stages of experimental arthritis: no clinical effect of therapeutic IL-23p19 inhibition in collagen-induced arthritis
Published in PloS one (28-02-2013)“…IL-23p19 deficient mice have revealed a critical role of IL-23 in the development of experimental autoimmune diseases, such as collagen-induced arthritis…”
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1,25(OH)2D3 and dexamethasone additively suppress synovial fibroblast activation by CCR6+ T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade
Published in Arthritis research & therapy (20-09-2018)“…Background Despite recent improvements in the treatment of rheumatoid arthritis (RA), an insufficient treatment response and the development of treatment…”
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Transition Probabilities from Pollination to Establishment in a Rare Dioecious Shrub Species (Rhamnus ludovici-salvatoris) in Two Habitats
Published in The Journal of ecology (01-06-2003)“…1 We elucidated the critical life stages and processes in the recruitment of Rhamnus ludovici-salvatoris, a dioecious shrub endemic to the Balearic Islands…”
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Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis
Published in PloS one (20-11-2015)“…Dendritic cells (DCs) are professional antigen presenting cells that have the dual ability to stimulate immunity and maintain tolerance. However, the…”
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Loss of IL‐22 inhibits autoantibody formation in collagen‐induced arthritis in mice
Published in European journal of immunology (01-06-2016)“…Interleukin 22 (IL‐22) expression is associated with increased joint destruction and disease progression in rheumatoid arthritis (RA). Although IL‐22 is…”
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Absence of Interleukin‐17 Receptor A Signaling Prevents Autoimmune Inflammation of the Joint and Leads to a Th2‐like Phenotype in Collagen‐Induced Arthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-02-2014)“…Objective Interleukin‐17A (IL‐17A) signals through the IL‐17 receptor (IL‐17R) A/C heterodimer. IL‐17RA serves as a common receptor subunit for several IL‐17…”
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SKELETAL MICROSTRUCTURE OF HELENS, LATERAL SPINES OF HYOLITHIDS
Published in Palaeontology (01-09-2007)“…: In hyolithids the skeleton consists of four elements: a conch, an operculum and a pair of long, logarithmically curved ‘spines’ called helens. These last…”
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Critical stages in the recruitment process of Rhamnus alaternus L
Published in Annals of botany (01-06-2004)“…Background and Aims: Rhamnus alaternus is a Mediterranean shrub commonly used in reforestation programs. Although several aspects of its reproductive biology…”
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