Search Results - "Murthy, Rachna"

Sirolimus (rapamycin) for the targeted treatment of the fibrotic sequelae of Graves’ orbitopathy by Roos, Jonathan C. P., Murthy, Rachna

“…Background Rapamycin (alternatively known as sirolimus) is a macrolide immunosuppressant commonly used for organ transplantation. It acts both on lymphocytes…”
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Serial TSH-receptor antibody levels to guide the management of thyroid eye disease: the impact of smoking, immunosuppression, radio-iodine, and thyroidectomy by Roos, Jonathan C. P., Paulpandian, Vignesh, Murthy, Rachna

“…The Thyrotropin receptor antibody (TRAb) is the main driver of Graves’ disease (GD) and its most common extra-thyroidal manifestation: thyroid eye disease…”
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Thyrotropin Receptor Autoantibody Assessment in Thyroid Eye Disease: Does the Assay Type Matter? by Moledina, Malik, Roos, Jonathan, Murthy, Rachna

“…Thyroid receptor antibodies can quantify thyroid eye disease activity, predict outcomes and aid timing of interventions. The type and generation of assay is…”
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Clinical pathophysiology of thyroid eye disease: The Cone Model by Meyer, Paul, Das, Tilak, Ghadiri, Nima, Murthy, Rachna, Theodoropoulou, Sofia

“…The clinical features of thyroid eye disease are dictated by the orbit’s compartmentalisation; particularly, the muscle cone, which is delimited by the rectus…”
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Fornix Fat Prolapse as a Sign for Involutional Entropion by Beigi, Bijan, MD, FRCOphth, Kashkouli, Mohsen Bahmani, MD, Shaw, Andrew, MRCOphth, Murthy, Rachna, MRCOphth

“…Objective To compare horizontal and vertical laxity of lower eyelids in patients with unilateral lower eyelid involutional entropion, introduce a reliable and…”
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Improving aseptic injection standards in aesthetic clinical practice by Murthy, Rachna, Eccleston, David, Mckeown, Darren, Parikh, Apul, Shotter, Sophie

“…The rise in popularity and demand for nonsurgical injectable aesthetic procedures is inherently accompanied by an increase in reported complications,…”
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Update on the clinical assessment and management of thyroid eye disease by Roos, Jonathan C.P, Murthy, Rachna

“…PURPOSE OF REVIEWTo offer an update on advances and controversies in the assessment, investigation and treatment of thyroid eye disease (TED), a disfiguring…”
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Comment on: Epimax-related ocular surface toxicity (EROST): the Glasgow experience by Sullivan, Amy Gallant, Murthy, Rachna, Roos, Jonathan C. P.

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Periocular hyaluronic acid fillers: applications, implications, complications by Murthy, Rachna, Roos, Jonathan C.P, Goldberg, Robert A

“…PURPOSE OF REVIEWThe use of dermal filler in the periocular area is increasing – both for functional and aesthetic indications. Hyaluronic acid fillers…”
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T2-relaxation mapping and fat fraction assessment to objectively quantify clinical activity in thyroid eye disease: an initial feasibility study by Das, Tilak, Roos, Jonathan C. P., Patterson, Andrew J., Graves, Martin J., Murthy, Rachna

“…Imaging in thyroid eye disease (TED) is used to exclude other diagnoses, assess for apical crowding and plan surgery. But to quantify TED activity objectively,…”
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Teprotumumab for Active Thyroid Eye Disease by Roos, Jonathan C P, Hyry, Hanna I, Murthy, Rachna

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Inhibition of Fibrotic Contraction by Sirolimus (Rapamycin) in an Ex Vivo Model of Thyroid Eye Disease by Roos, Jonathan C. P., Eglitis, Viesturs, Murthy, Rachna

“…Background: Thyroid eye disease (TED) is characterized by orbital inflammation and complicated by extraocular muscle fibrosis. Treatment with…”
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Comment on: A British Ophthalmic Surveillance Unit (BOSU) study into dysthyroid optic neuropathy in the United Kingdom by Roos, Jonathan C. P., Murthy, Rachna

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TFOS Lifestyle: Impact of cosmetics on the ocular surface by Sullivan, David A., da Costa, Alexandre X., Del Duca, Ester, Doll, Tracy, Grupcheva, Christina N., Lazreg, Sihem, Liu, Su-Hsun, McGee, Selina R., Murthy, Rachna, Narang, Purvasha, Ng, Alison, Nistico, Steven, O'Dell, Leslie, Roos, Jonathan, Shen, Joanne, Markoulli, Maria

“…In this report the use of eye cosmetic products and procedures and how this represents a lifestyle challenge that may exacerbate or promote the development of…”
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Factors influencing pre‐injection aspiration for hyaluronic acid fillers: A systematic literature review and meta‐analysis by Kapoor, Krishan Mohan, Murthy, Rachna, Hart, Sarah Linden Alethea, Cattin, Teresa Ann, Nola, Paul Fred, Rossiter, Anthony Paul, Singh, Rashpal, Singh, Shobhna

“…Pre‐injection aspiration of hyaluronic acid filler is a well‐recognized yet controversial safety technique. Many consider aspiration to be an important safety…”
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Immune reconstitution after alemtuzumab therapy for multiple sclerosis triggering Graves’ orbitopathy: a case series by Roos, Jonathan C. P., Moran, Carla, Chatterjee, V. Krishna, Jones, Joanne, Coles, Alasdair, Murthy, Rachna

“…Alemtuzumab—a monoclonal antibody targeting the CD52 glycoprotein expressed by most mature leucocytes—effectively decreases relapse rate and disability…”
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Suture midface suspension by Ugurbas, Suat H, Goldberg, Robert A, McCann, John D, Shorr, Norman, Murthy, Rachna, Ben Simon, Guy J

“…To describe a simple and effective facelift technique useful as an adjunct to other oculoplastic procedures Retrospective, non-comparative case series. Thirty…”
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Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment by Kolko, Miriam, Gazzard, Gus, Baudouin, Christophe, Beier, Sofie, Brignole-Baudouin, Françoise, Cvenkel, Barbara, Fineide, Fredrik, Hedengran, Anne, Hommer, Anton, Jespersen, Erik, Messmer, Elisabeth M., Murthy, Rachna, Sullivan, Amy Gallant, Tatham, Andrew J., Utheim, Tor Paaske, Vittrup, Marijke, Sullivan, David A.

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Teprotumumab for Active Thyroid Eye Disease by Kim, Stephanie, Patzek, Sophie, Roos, Jonathan C.P, Hyry, Hanna I, Murthy, Rachna, Douglas, Raymond S, Kahaly, George J

“…To the Editor: Douglas and colleagues (Jan. 23 issue) 1 report exciting results from their phase 3 trial of teprotumumab therapy for Graves’ orbitopathy, which…”
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Silent sinus syndrome by Cobb, Alistair R.M, Murthy, Rachna, Cousin, Gary C.S, El-Rasheed, Adel, Toma, Abbad, Uddin, Jimmy, Manisali, Mehmet

“…Abstract Silent sinus syndrome is defined as a spontaneous and progressive enophthalmos and hypoglobus with hypoplasia of the maxillary sinus and resorption of…”
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