Search Results - "Murthy, R. K."

Synthesis, Electronic Structure, UV-Vis, Wave Function, and Molecular Docking Studies of Schiff Base (Z)-N-(Thiazol-2-yl)-4-((Thiophene-2-ylmethylene)Amino)Benzenesulfonamide by Kanagavalli, A., Thilagavathi, G., Jayachitra, R., Elangovan, N., Sowrirajan, S., Shadakshara Murthy, K. R., Thomas, Renjith

“…The (Z)-N-(thiazol-2-yl)-4-((thiophene-2-ylmethylene)amino)benzenesulfonamide (TH2TH) were synthesized. The geometry was optimized by density functional theory…”
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CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells by Yang, Xiaojing, Karuturi, R K Murthy, Sun, Feng, Aau, Meiyee, Yu, Kun, Shao, Rongguang, Miller, Lance D, Tan, Patrick Boon Ooi, Yu, Qiang

“…CDKN1C (encoding tumor suppressor p57(KIP2)) is a cyclin-dependent kinase (CDK) inhibitor whose family members are often transcriptionally downregulated in…”
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BCL2A1 regulates Canady Helios Cold Plasma-induced cell death in triple-negative breast cancer by Murthy, Saravana R. K., Cheng, Xiaoqian, Zhuang, Taisen, Ly, Lawan, Jones, Olivia, Basadonna, Giacomo, Keidar, Michael, Canady, Jerome

“…Breast cancer is the leading cause of cancer death among women. Triple-negative breast cancer (TNBC) has a poor prognosis and frequently relapses early…”
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The synergistic effect of Canady Helios cold atmospheric plasma and a FOLFIRINOX regimen for the treatment of cholangiocarcinoma in vitro by Jones, Olivia, Cheng, Xiaoqian, Murthy, Saravana R. K., Ly, Lawan, Zhuang, Taisen, Basadonna, Giacomo, Keidar, Michael, Canady, Jerome

“…Cholangiocarcinoma (CCA) is a rare biliary tract cancer with a low five-year survival rate and high recurrence rate after surgical resection. Currently…”
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New Roles of Carboxypeptidase E in Endocrine and Neural Function and Cancer by Cawley, Niamh X, Wetsel, William C, Murthy, Saravana R. K, Park, Joshua J, Pacak, Karel, Loh, Y. Peng

“…Carboxypeptidase E (CPE) or carboxypeptidase H was first discovered in 1982 as an enkephalin-convertase that cleaved a C-terminal basic residue from enkephalin…”
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FOXQ1 Regulates Epithelial-Mesenchymal Transition in Human Cancers by YUANYUAN QIAO, XIA JIANG, THENG LEE, Shuet, MURTHY KARUTURI, R. K, SHING CHUAN HOOI, QIANG YU

“…Epithelial-mesenchymal transition (EMT) in cancer cells plays a pivotal role in determining metastatic prowess, but knowledge of EMT regulation remains…”
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Citronellal as a Promising Candidate for Alzheimer’s Disease Treatment: A Comprehensive Study on In Silico and In Vivo Anti-Acetylcholine Esterase Activity by K, Pavani, Prasanth, D S. N. B. K, Shadakshara, Murthy K. R, Ahmad, Sheikh F, Seemaladinne, Ramanjaneyulu, Rudrapal, Mithun, Pasala, Praveen Kumar

“…One of the primary therapeutic approaches for managing Alzheimer’s disease (AD) involves the modulation of Acetylcholine esterase (AChE) activity to elevate…”
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Non-Dominated Sorting-Based Hybrid Optimization Technique for Multi-Objective Hydrothermal Scheduling by Nadakuditi, Gouthamkumar, Pulluri, Harish, Dahiya, Preeti, Murthy, K. S. R., Varma, P. Srinivasa, Bajaj, Mohit, Altameem, Torki, El-Shafai, Walid, Fouda, Mostafa M.

“…Short-term hydrothermal scheduling problem plays an important role in maintaining a high degree of economy and reliability in power system operational…”
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Oxidative Stress and Mitogen-Activated Protein Kinase Phosphorylation Mediate Ammonia-Induced Cell Swelling and Glutamate Uptake Inhibition in Cultured Astrocytes by Jayakumar, A. R, Panickar, K. S, Murthy, Ch. R. K, Norenberg, M. D

“…Hepatic encephalopathy (HE) is a major neurological complication in patients with severe liver failure. Elevated levels of ammonia have been strongly…”
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A Novel Single Nucleotide T980C Polymorphism in the Human Carboxypeptidase E Gene Results in Loss of Neuroprotective Function by Cong, Lin, Cheng, Yong, Cawley, Niamh X, Murthy, Saravana R K, Loh, Y Peng

“…Report of a human with a homozygous truncating null mutation of the Carboxypeptidase E (CPE) gene with endocrinological and neurological deficits prompted us…”
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Clinicopathological and surgical factors associated with long-term survival in patients with HER2-positive metastatic breast cancer by Harano, K., Lei, X., Gonzalez-Angulo, A. M., Murthy, R. K., Valero, V., Mittendorf, E. A., Ueno, N. T., Hortobagyi, G. N., Chavez-MacGregor, M.

“…Trastuzumab-based treatment has dramatically improved the outcomes of HER2-positive (HER2+) metastatic breast cancer (MBC) patients, with some patients…”
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Doubly Ortho-Linked Quinoxaline/Diphenylfluorene Hybrids as Bipolar, Fluorescent Chameleons for Optoelectronic Applications by Chen, Chien-Tien, Wei, Yi, Lin, Jin-Sheng, Moturu, Murthy V. R. K, Chao, Wei-San, Tao, Yu-Tai, Chien, Chin-Hsiung

“…The titled dipolar hybrids bearing a central quinoxaline-fused dibenzosuberene optoelectronic unit with functional C5 and C8 appendages and spiro-fluorene…”
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The co-operonic PE25/PPE41 protein complex of Mycobacterium tuberculosis elicits increased humoral and cell mediated immune response by Tundup, Smanla, Pathak, Niteen, Ramanadham, M, Mukhopadhyay, Sangita, Murthy, K J R, Ehtesham, Nasreen Z, Hasnain, Seyed E

“…Many of the PE/PPE proteins are either surface localized or secreted outside and are thought to be a source of antigenic variation in the host. The exact role…”
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Molecular Simulation-based Combinatorial Modeling and Antioxidant Activities of Zingiberaceae Family Rhizomes by Usha, Talambedu, Pradhan, Sushen, Goyal, Arvind Kumar, Dhivya, Shanmugarajan, Kumar, H P Prashanth, Singh, Manoj Kumar, Joshi, Neelu, Basistha, Bharat Chandra, Murthy, K R Siddalinga, Selvaraj, Saravanakumar, Middha, Sushil Kumar

“…The main aim of this scientific report was to investigate a series of phytochemicals and the pharmacology of four plants found at higher altitude in the ginger…”
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Carboxypeptidase E Protects Hippocampal Neurons During Stress in Male Mice by Up-regulating Pro-survival BCL2 Protein Expression by Murthy, S. R. K, Thouennon, E, Li, W.-S, Cheng, Y, Bhupatkar, J, Cawley, N. X, Lane, M, Merchenthaler, I, Loh, Y. P

“…Prolonged chronic stress causing elevated plasma glucocorticoids leads to neurodegeneration. Adaptation to stress (allostasis) through neuroprotective…”
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Canady Helios Cold Plasma Induces Breast Cancer Cell Death by Oxidation of Histone mRNA by Cheng, Xiaoqian, Murthy, Saravana R. K., Zhuang, Taisen, Ly, Lawan, Jones, Olivia, Basadonna, Giacomo, Keidar, Michael, Kanaan, Yasmine, Canady, Jerome

“…Breast cancer is the most common cancer among women worldwide. Its molecular receptor marker status and mutational subtypes complicate clinical therapies. Cold…”
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Carboxylesterases from the seeds of an underutilized legume, Mucuna pruriens; isolation, purification and characterization by Chandrashekharaiah, K.S., Ramachandra Swamy, N., Siddalinga Murthy, K.R.

“…Two carboxylesterases (ME-III and ME-IV) have been purified and characterized from the seeds of Mucuna pruriens. Both the enzymes were inhibited by…”
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Managing Social Organizations: Experiences and Challenges by Ravichandran, N., Venkataramanaiah, S., Gajiwala, Uday, Pandey, Rahul, Venkat, Shridhar, Rao, I. V. Subba, Murthy, K. R. S., Manikutty, S., Raghuram, G.

“…The colloquium presents multiple perspectives on managing social organizations. Social organizations have emerged from not-for-profit organizations. They meet…”
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Canady Cold Helios Plasma Reduces Soft Tissue Sarcoma Viability by Inhibiting Proliferation, Disrupting Cell Cycle, and Inducing Apoptosis: A Preliminary Report by Ly, Lawan, Cheng, Xiaoqian, Murthy, Saravana R. K., Jones, Olivia Z., Zhuang, Taisen, Gitelis, Steven, Blank, Alan T., Nissan, Aviram, Adileh, Mohammad, Colman, Matthew, Keidar, Michael, Basadonna, Giacomo, Canady, Jerome

“…Soft tissue sarcomas (STS) are a rare and highly heterogeneous group of solid tumors, originating from various types of connective tissue. Complete removal of…”
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Mutations in RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy by Kumaramanickavel, Govindasamy, Rathmann, Michaela, Denton, Michael J, Srikumari, C.R. Srisailapathy, Gu, Su-min, Thompson, Debra A, Lorenz, Birgit, Finckh, Ulrich, Murthy, K.R, Gal, Andreas, Nicoletti, Aileen

“…Autosomal recessive childhood-onset severe retinal dystrophy (arCSRD) designates a heterogeneous group of disorders affecting rod and cone photoreceptors…”
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