Search Results - "Murthy, R."
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National Mental Health Survey of India 2015-2016
Published in Indian journal of psychiatry (01-01-2017)“…[1] [INLINE:1] Media referred to the findings of the report as follows: “India needs to talk about mental illness;”[2] “Every sixth Indian needs mental health…”
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Scaffold: a novel carrier for cell and drug delivery
Published in Critical reviews in therapeutic drug carrier systems (2012)“…Scaffolds are implants or injects, which are used to deliver cells, drugs, and genes into the body. Different forms of polymeric scaffolds for cell/drug…”
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3
Glycerolipid Metabolism and Signaling in Health and Disease
Published in Endocrine reviews (01-10-2008)“…Maintenance of body temperature is achieved partly by modulating lipolysis by a network of complex regulatory mechanisms. Lipolysis is an integral part of the…”
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4
Nutrient-Induced Metabolic Stress, Adaptation, Detoxification, and Toxicity in the Pancreatic β-Cell
Published in Diabetes (New York, N.Y.) (01-03-2020)“…Paraphrasing the Swiss physician and father of toxicology Paracelsus (1493-1541) on chemical agents used as therapeutics, "the dose makes the poison," it is…”
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5
Recent approaches of lipid-based delivery system for lymphatic targeting via oral route
Published in Journal of drug targeting (01-12-2014)“…Abstract Lymphatic system is a key target in research field due to its distinctive makeup and huge contributing functions within the body. Intestinal lymphatic…”
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Formulation and characterization of intranasal mucoadhesive nanoparticulates and thermo-reversible gel of levodopa for brain delivery
Published in Drug development and industrial pharmacy (01-07-2014)“…Abstract Levodopa is the drug of choice in the treatment of Parkinson's disease but it exhibits low oral bioavailability (30%) and very low brain uptake due to…”
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7
Lipid-associated metabolic signalling networks in pancreatic beta cell function
Published in Diabetologia (01-01-2020)“…Significant advances have been made in deciphering the mechanisms underlying fuel-stimulated insulin secretion by pancreatic beta cells. The contribution of…”
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pH-Sensitive liposomes-principle and application in cancer therapy
Published in Journal of pharmacy and pharmacology (01-04-2007)“…The purpose of this review is to provide an insight into the different aspects of pH‐sensitive liposomes. The review consists of 6 parts: the first introduces…”
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9
Metabolic Signaling in Fuel-Induced Insulin Secretion
Published in Cell metabolism (06-08-2013)“…The pancreatic islet β cell senses circulating levels of calorigenic nutrients to secrete insulin according to the needs of the organism. Altered insulin…”
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10
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis
Published in Proceedings of the National Academy of Sciences - PNAS (04-12-2007)“…Elevated expression of members of the BCL-2 pro-survival family of proteins can confer resistance to apoptosis in cancer cells. Small molecule obatoclax…”
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11
The multi-faces of Angptl8 in health and disease: Novel functions beyond lipoprotein lipase modulation
Published in Progress in lipid research (01-11-2020)“…Angiopoietin-like protein (ANGPTL) family members, mainly ANGPTL3, ANGPTL4 and ANGPTL8, are physiological inhibitors of lipoprotein lipase (LPL), and play a…”
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12
The critical role of bisphosphonates to target bone cancer metastasis: an overview
Published in Journal of drug targeting (01-01-2015)“…Abstract Cancer becomes the leading cause of deaths worldwide, including breast cancer, prostate cancer and lung cancer that preferentially metastasize to bone…”
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Development, optimization and evaluation of surfactant-based pulmonary nanolipid carrier system of paclitaxel for the management of drug resistance lung cancer using Box-Behnken design
Published in Drug delivery (23-07-2016)“…In the present study, nanostructured lipid carriers (NLCs) along with various surfactants loaded with paclitaxel (PTX) were prepared by an emulsification…”
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Effects of mobile Health (mHealth) application on cervical cancer prevention knowledge and screening among women social support groups with low-socioeconomic status in Mysuru city, Southern India
Published in PloS one (01-09-2022)“…Background Cervical cancer is an important area of action because of the mortality and morbidity of the disease, and the potential for effective prevention by…”
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Tucatinib versus placebo added to trastuzumab and capecitabine for patients with pretreated HER2+ metastatic breast cancer with and without brain metastases (HER2CLIMB): final overall survival analysis
Published in Annals of oncology (01-03-2022)“…In the primary analysis of the HER2CLIMB trial, tucatinib added to trastuzumab and capecitabine significantly improved overall survival (OS) and…”
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Surfactant-based drug delivery systems for treating drug-resistant lung cancer
Published in Drug delivery (23-03-2016)“…Among all cancers, lung cancer is the major cause of deaths. Lung cancer can be categorized into two classes for prognostic and treatment purposes: small cell…”
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Living with cancer: Urgent need for emotional health support
Published in Indian journal of cancer (01-07-2020)Get full text
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Advances in nanomedicines for malaria treatment
Published in Advances in colloid and interface science (01-12-2013)“…Malaria is an infectious disease that mainly affects children and pregnant women from tropical countries. The mortality rate of people infected with malaria…”
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Glycerolipid/free fatty acid cycle and islet β-cell function in health, obesity and diabetes
Published in Molecular and cellular endocrinology (28-04-2012)“…► We describe the organization of the glycerolipid/free fatty acid cycle in the β-cell. ► We discuss the significance of β-cell GL/FFA cycle in glucose…”
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Stabilizability of Linear Dynamical Systems Using Sparse Control Inputs
Published in IEEE transactions on automatic control (01-08-2023)“…The stabilizability of a linear dynamical system (LDS) refers to the existence of control inputs that drive the system state to zero. In this article, we…”
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