Search Results - "Murthy, N Megha"

Copy number variations burden on miRNA genes reveals layers of complexities involved in the regulation of pathways and phenotypic expression by Veerappa, Avinash M, Murthy, Megha N, Vishweswaraiah, Sangeetha, Lingaiah, Kusuma, Suresh, Raviraj V, Nachappa, Somanna Ajjamada, Prashali, Nelchi, Yadav, Sangeetha Nuggehalli, Srikanta, Manjula Arsikere, Manjegowda, Dinesh S, Seshachalam, Keshava B, Ramachandra, Nallur B

“…MicroRNAs are involved in post-transcriptional down-regulation of gene expression. Variations in miRNA genes can severely affect downstream-regulated genes and…”
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Increased brain expression of GPNMB is associated with genome wide significant risk for Parkinson’s disease on chromosome 7p15.3 by Murthy, Megha N., Blauwendraat, Cornelis, Guelfi, Sebastian, Hardy, John, Lewis, Patrick A., Trabzuni, Daniah

“…Genome wide association studies (GWAS) for Parkinson’s disease (PD) have previously revealed a significant association with a locus on chromosome 7p15.3,…”
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High-resolution arrays reveal burden of copy number variations on Parkinson disease genes associated with increased disease risk in random cohorts by Murthy, Megha N., Veerappa, Avinash M., Seshachalam, Keshava B., Ramachandra, Nallur B.

“…Background: Parkinson disease (PD) is a neurological disease responsible for a considerable rate of mortality and morbidity in the society. Since the symptoms…”
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Type 2 diabetes mellitus disease risk genes identified by genome wide copy number variation scan in normal populations by Prabhanjan, Manasa, Suresh, Raviraj V, Murthy, Megha N, Ramachandra, Nallur B

“…Highlights • CNV analysis was carried out on a total of 1715 individuals from 12 populations. • 34.4% of the total population to be under CNV burden for T2DM…”
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Insertion-deletions burden in copy number polymorphisms of the Tibetan population by Veerappa, Avinash M, Vishweswaraiah, Sangeetha, Lingaiah, Kusuma, Murthy, N Megha, Suresh, Raviraj V, Belur, Keshava, Ramachandra, Nallur B, Tejaswini, Patel, Niveditha B, Gowda, P K Supriya

“…Many studies have been conducted to identify either insertions-deletions (inDels) or copy number variations (CNVs) in humans, but few studies have been…”
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Impact of copy number variations burden on coding genome in humans using integrated high resolution arrays by Veerappa, Avinash M, Lingaiah, Kusuma, Vishweswaraiah, Sangeetha, Murthy, Megha N, Suresh, Raviraj V, Manjegowda, Dinesh S, Ramachandra, Nallur B

“…Copy number variations (CNVs) alter the transcriptional and translational levels of genes by disrupting the coding structure and this burden of CNVs seems to…”
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Copy Number Variations Burden on miRNA Genes Reveals Layers of Complexities Involved in the Regulation of Pathways and Phenotypic Expression: e90391 by Veerappa, Avinash M, N, Megha Murthy, Vishweswaraiah, Sangeetha, Lingaiah, Kusuma, Suresh, Raviraj V, Nachappa, Somanna Ajjamada, Prashali, Nelchi, Yadav, Sangeetha Nuggehalli, Srikanta, Manjula Arsikere, Manjegowda, Dinesh S

“…MicroRNAs are involved in post-transcriptional down-regulation of gene expression. Variations in miRNA genes can severely affect downstream-regulated genes and…”
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Prioritization of differentially expressed genes in Substantia nigra transcriptomes of Parkinson's disease reveals key protein interactions and pathways by Murthy, Megha N., Ramachandra, Nallur B.

“…Parkinson's disease (PD) is a progressive neurodegenerative disorder and a major cause of disability in the elderly population. The search for potential…”
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