Search Results - "Murthy, Kausalya"

Dual role for microtubules in regulating cortical contractility during cytokinesis by Murthy, Kausalya, Wadsworth, Patricia

“…Microtubules stimulate contractile-ring formation in the equatorial cortex and simultaneously suppress contractility in the polar cortex; how they accomplish…”
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Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG by Iyer, Sangeetha, Sam, Feba S, DiPrimio, Nina, Preston, Graeme, Verheijen, Jan, Murthy, Kausalya, Parton, Zachary, Tsang, Hillary, Lao, Jessica, Morava, Eva, Perlstein, Ethan O

“…Phosphomannomutase 2 deficiency, or PMM2-CDG, is the most common congenital disorder of glycosylation and affects over 1000 patients globally. There are no…”
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Cargo crowding at actin‐rich regions along axons causes local traffic jams by Sood, Parul, Murthy, Kausalya, Kumar, Vinod, Nonet, Michael L., Menon, Gautam I., Koushika, Sandhya P.

“…Steady axonal cargo flow is central to the functioning of healthy neurons. However, a substantial fraction of cargo in axons remains stationary up to several…”
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Quantification of microtubule nucleation, growth and dynamics in wound-edge cells by Salaycik, Kimberly J, Fagerstrom, Carey J, Murthy, Kausalya, Tulu, U. Serdar, Wadsworth, Patricia

“…Mammalian cells develop a polarized morphology and migrate directionally into a wound in a monolayer culture. To understand how microtubules contribute to…”
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Preferential transport of synaptic vesicles across neuronal branches is regulated by the levels of the anterograde motor UNC-104/KIF1A in vivo by Vasudevan, Amruta, Ratnakaran, Neena, Murthy, Kausalya, Kumari, Shikha, Hall, David H, Koushika, Sandhya P

“…Asymmetric transport of cargo across axonal branches is a field of active research. Mechanisms contributing to preferential cargo transport along specific…”
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Myosin-II-Dependent Localization and Dynamics of F-Actin during Cytokinesis by Murthy, Kausalya, Wadsworth, Patricia

“…Background: The assembly of an F-actin- and myosin-II-containing contractile ring (CR) is required for cytokinesis in eukaryotic cells. Interactions between…”
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Transport of synaptic vesicles is modulated by vesicular reversals and stationary cargo clusters by Vasudevan, Amruta, Maiya, Reshma, Venkatesh, Keertana, Kumar, Vinod, Sood, Parul, Murthy, Kausalya, Koushika, Sandhya P, Menon, Gautam I

“…Stationary clusters of vesicles are a prominent feature of axonal transport, but little is known about their physiological and functional relevance to axonal…”
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In vivo imaging of retrogradely transported synaptic vesicle proteins in C. elegans neurons by Murthy, Kausalya T., Bhat, Jaffar, Koushika, Sandhya P.

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In vivo Imaging of Retrogradely Transported Synaptic Vesicle Proteins in Caenorhabditis elegans Neurons by Murthy, Kausalya, Bhat, Jaffar M., Koushika, Sandhya P.

“…Axonal transport is an essential process that carries cargoes in the anterograde direction to the synapse and in the retrograde direction back to the cell…”
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Myosin-II-Dependent Localization and Dynamics of F-Actin during Cytokinesis by Murthy, Kausalya, Wadsworth, Patricia

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Organization and dynamics of actin and myosin during cytokinesis in mammalian epithelial cells by Murthy, Kausalya

“…Cytokinesis, the process of physically separating cells for division, requires the precise orchestration of numerous physical, mechanical, chemical and…”
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