Search Results - "Murthy, J Narashima"

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    Recent advances in molecular modeling and medicinal chemistry aspects of phospho-glycoprotein

    Recent advances in molecular modeling and medicinal chemistry aspects of phospho-glycoprotein by Srinivas, E, Murthy, J Narashima, Rao, A Raghu Ram, Sastry, G Narahari

    Published in Current drug metabolism (01-02-2006)
    “…Phospho-glycoprotein (P-gp) is an efflux transporter expressed in many organs (ex: kidney, lung, liver and spleen) and in hormone producing or responsive…”
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    Active site acidic residues and structural analysis of modelled human aromatase: a potential drug target for breast cancer

    Active site acidic residues and structural analysis of modelled human aromatase: a potential drug target for breast cancer by Murthy, J Narashima, Nagaraju, M, Sastry, G Madhavi, Rao, A Raghuram, Sastry, G Narahari

    Published in Journal of computer-aided molecular design (01-12-2005)
    “…This study sheds new light on the role of acidic residues present in the active site cavity of human aromatase. Eight acidic residues (E129, D222, E245, E302,…”
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