Search Results - "Murta, Silvane MF"

Molecular characterization of the hexose transporter gene in benznidazole resistant and susceptible populations of Trypanosoma cruzi by dos Santos, Paula F, Ruiz, Jerônimo C, Soares, Rodrigo P P, Moreira, Douglas S, Rezende, Antônio M, Folador, Edson L, Oliveira, Guilherme, Romanha, Alvaro J, Murta, Silvane MF

“…BACKGROUND: Hexose transporters (HT) are membrane proteins involved in the uptake of energy-supplying glucose and other hexoses into the cell. Previous studies…”
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Phylogenetic analysis of Biomphalaria tenagophila (Orbigny, 1835) (Mollusca: Gastropoda) by Jannotti-Passos, Liana K, Ruiz, Jeronimo C, Caldeira, Roberta L, Murta, Silvane M.F, Coelho, Paulo Marcos Z, Carvalho, Omar S

“…Mitochondrial DNA of Biomphalaria tenagophila , a mollusc intermediate host of Schistosoma mansoni in Brazil, was sequenced and characterised. The genome size…”
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Retention and loss of RNA interference pathways in trypanosomatid protozoans by Lye, Lon-Fye, Owens, Katherine, Shi, Huafang, Murta, Silvane M F, Vieira, Ana Carolina, Turco, Salvatore J, Tschudi, Christian, Ullu, Elisabetta, Beverley, Stephen M

“…RNA interference (RNAi) pathways are widespread in metaozoans but the genes required show variable occurrence or activity in eukaryotic microbes, including…”
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Epidermal growth factor receptors, testosterone levels and parotid gland changes in rats infected with Trypanosoma cruzi by Aguirre, Kezia LH, Alves, José B, Silva, Gerluza AB, Cardoso, Jarbas E, Murta, Silvane MF, Ferreira, Anderson J

“…It has been demonstrated that parotid glands of rats infected with Trypanosoma cruzi present severe histological alterations; changes include reduction in…”
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Antibacterial, antifungal and antiprotozoal activities of fungal communities present in different substrates from Antarctica by Gonçalves, Vivian N., Carvalho, Camila R., Johann, Susana, Mendes, Graziele, Alves, Tânia M. A., Zani, Carlos L., Junior, Policarpo A. S., Murta, Silvane M. F., Romanha, Alvaro J., Cantrell, Charles L., Rosa, Carlos A., Rosa, Luiz H.

“…Antarctica is a pristine and extreme environment that represents a unique opportunity for taxonomic, ecological and biotechnological studies of the…”
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Diversity and bioprospection of fungal community present in oligotrophic soil of continental Antarctica by Godinho, Valéria M., Gonçalves, Vívian N., Santiago, Iara F., Figueredo, Hebert M., Vitoreli, Gislaine A., Schaefer, Carlos E. G. R., Barbosa, Emerson C., Oliveira, Jaquelline G., Alves, Tânia M. A., Zani, Carlos L., Junior, Policarpo A. S., Murta, Silvane M. F., Romanha, Alvaro J., Kroon, Erna Geessien, Cantrell, Charles L., Wedge, David E., Duke, Stephen O., Ali, Abbas, Rosa, Carlos A., Rosa, Luiz H.

“…We surveyed the diversity and capability of producing bioactive compounds from a cultivable fungal community isolated from the cold-arid, oligotrophic soil of…”
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Phosphoproteomic analysis of wild-type and antimony-resistant Leishmania braziliensis lines by 2D-DIGE technology by Moreira, Douglas de Souza, Pescher, Pascale, Laurent, Christine, Lenormand, Pascal, Späth, Gerald F., Murta, Silvane M. F.

“…Protein phosphorylation is one of the most studied post‐translational modifications that is involved in different cellular events in Leishmania. In this study,…”
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Molecular characterization and functional analysis of pteridine reductase in wild-type and antimony-resistant Leishmania lines by de Souza Moreira, Douglas, Ferreira, Rafael Fernandes, Murta, Silvane M.F.

“…Pteridine reductase (PTR1) is an NADPH-dependent reductase that participates in the salvage of pteridines, which are essential to maintain growth of…”
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Silver and Nitrate Oppositely Modulate Antimony Susceptibility through Aquaglyceroporin 1 in Leishmania (Viannia) Species by Andrade, Juvana M, Baba, Elio H, Machado-de-Avila, Ricardo A, Chavez-Olortegui, Carlos, Demicheli, Cynthia P, Frézard, Frédéric, Monte-Neto, Rubens L, Murta, Silvane M F

“…Antimony (Sb) resistance in leishmaniasis chemotherapy has become one of the major challenges to the control of this spreading worldwide public health problem…”
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Regulated expression of the Leishmania major surface virulence factor lipophosphoglycan using conditionally destabilized fusion proteins by Madeira da Silva, Luciana, Owens, Katherine L, Murta, Silvane M.F, Beverley, Stephen M

“…Surface glycoconjugates play important roles in the infectious cycle of Leishmania major, including the abundant lipophosphoglycan (LPG) implicated in parasite…”
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Methylene tetrahydrofolate dehydrogenase/cyclohydrolase and the synthesis of 10-CHO-THF are essential in Leishmania major by Murta, Silvane M.F, Vickers, Tim J, Scott, David A, Beverley, Stephen M

“…10-Formyl tetrahydrofolate (10-CHO-THF) is a key metabolite in C1 carbon metabolism, arising through the action of formate-tetrahydrofolate ligase (FTL) and/or…”
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Identification of two p23 co‐chaperone isoforms in Leishmania braziliensis exhibiting similar structures and Hsp90 interaction properties despite divergent stabilities by Batista, Fernanda A.H, Almeida, Glessler S, Seraphim, Thiago V, Silva, Kelly P, Murta, Silvane M.F, Barbosa, Leandro R.S, Borges, Júlio C

“…The small acidic protein called p23 acts as a co‐chaperone for heat‐shock protein of 90 kDa (Hsp90) during its ATPase cycle. p23 proteins inhibit Hsp90 ATPase…”
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Biological activities of ophiobolin K and 6-epi-ophiobolin K produced by the endophytic fungus Aspergillus calidoustus by Rodrigues de Carvalho, Camila, Vieira, Mariana de Lourdes Almeida, Cantrell, Charles L, Wedge, David E, Alves, Tânia M.A, Zani, Carlos Leomar, Pimenta, Raphael Sanzio, Sales Junior, Policarpo A, Murta, Silvane M.F, Romanha, Alvaro J, Rosa, Carlos Augusto, Rosa, Luiz H

“…Endophytic fungi represent ubiquitous microbial organisms able to live in the tissues of different plants around the world and represent a prolific source of…”
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Molecular characterization of lipoamide dehydrogenase gene in Trypanosoma cruzi populations susceptible and resistant to benznidazole by dos Santos, Paula F., Moreira, Douglas S., Baba, Elio H., Volpe, Caroline M.O., Ruiz, Jerônimo C., Romanha, Alvaro J., Murta, Silvane M.F.

“…Lipoamide dehydrogenase (LipDH) is a flavin-containing disulfide oxidoreductase from the same group of thioredoxin reductase, glutathione reductase and…”
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Retention and Loss of RNA Interference Pathways in Trypanosomatid Protozoans: e1001161 by Lye, Lon-Fye, Owens, Katherine, Shi, Huafang, Murta, Silvane MF, Vieira, Ana Carolina, Turco, Salvatore J, Tschudi, Christian, Ullu, Elisabetta, Beverley, Stephen M

“…RNA interference (RNAi) pathways are widespread in metaozoans but the genes required show variable occurrence or activity in eukaryotic microbes, including…”
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Deletion of copies of the gene encoding old yellow enzyme (TcOYE), a NAD(P)H flavin oxidoreductase, associates with in vitro-induced benznidazole resistance in Trypanosoma cruzi by Murta, Silvane M.F., Krieger, Marco A., Montenegro, Luciana R., Campos, Fernanda F.M., Probst, Christian M., Ávila, Andréa R., Muto, Nair H., Oliveira, Regina C. de, Nunes, Luiz R., Nirdé, Philippe, Bruna-Romero, Oscar, Goldenberg, Samuel, Romanha, Alvaro J.

“…Old yellow enzyme (OYE) is a NAD(P)H flavin oxidoreductase that in Trypanosoma cruzi (TcOYE) catalyzes prostaglandin PGF2α synthesis and reduction of some…”
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The enzymes of the 10-formyl-tetrahydrofolate synthetic pathway are found exclusively in the cytosol of the trypanosomatid parasite Leishmania major by Vickers, Tim J., Murta, Silvane M.F., Mandell, Michael A., Beverley, Stephen M.

“…In most organisms 10-formyl-tetrahydrofolate (10-CHO-THF) participates in the synthesis of purines in the cytosol and formylation of mitochondrial initiator…”
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Characterization of a gene encoding alcohol dehydrogenase in benznidazole-susceptible and -resistant populations of Trypanosoma cruzi by Campos, Fernanda M.F., Liarte, Daniel B., Mortara, Renato A., Romanha, Alvaro J., Murta, Silvane M.F.

“…Alcohol dehydrogenases (ADH) are a class of oxidoreductases that catalyse the reversible oxidation of ethanol to acetaldehyde. In the human parasite…”
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Differential gene expression in Trypanosoma cruzi populations susceptible and resistant to benznidazole by Murta, Silvane M.F., Nogueira, Fernanda B., dos Santos, Paula F., Campos, Fernanda M.F., Volpe, Caroline, Liarte, Daniel B., Nirdé, Philippe, Probst, Christian M., Krieger, Marco A., Goldenberg, Samuel, Romanha, Alvaro J.

“…Differential gene expression in three pairs of Trypanosoma cruzi populations or clones susceptible or resistant to benznidazole (BZ) was investigated by…”
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Low Resolution Structural Studies Indicate that the Activator of Hsp90 ATPase 1 (Aha1) of Leishmania braziliensis Has an Elongated Shape Which Allows Its Interaction with Both N- and M-Domains of Hsp90. e66822 by Seraphim, Thiago V, Alves, Marina M, Silva, Indjara M, Gomes, Francisco ER, Silva, Kelly P, Murta, Silvane MF, Barbosa, Leandro RS, Borges, Julio C

“…The Hsp90 molecular chaperone is essential for protein homeostasis and in the maturation of proteins involved with cell-cycle control. The low ATPase activity…”
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