Search Results - "Murrell, P."

F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex by Murrell, Michael P., Gardel, Margaret L.

“…Here we develop a minimal model of the cell actomyosin cortex by forming a quasi-2D cross-linked filamentous actin (F-actin) network adhered to a model cell…”
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F-actin architecture determines the conversion of chemical energy into mechanical work by Sakamoto, Ryota, Murrell, Michael P.

“…Mechanical work serves as the foundation for dynamic cellular processes, ranging from cell division to migration. A fundamental driver of cellular mechanical…”
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Mechanical power is maximized during contractile ring-like formation in a biomimetic dividing cell model by Sakamoto, Ryota, Murrell, Michael P.

“…The spatial and temporal dynamics of forces in cells coordinate essential behaviors like division, polarization, and migration. While intracellular signaling…”
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Irreversibility in dynamical phases and transitions by Seara, Daniel S., Machta, Benjamin B., Murrell, Michael P.

“…Living and non-living active matter consumes energy at the microscopic scale to drive emergent, macroscopic behavior including traveling waves and coherent…”
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Cooperation of dual modes of cell motility promotes epithelial stress relaxation to accelerate wound healing by Staddon, Michael F, Bi, Dapeng, Tabatabai, A Pasha, Ajeti, Visar, Murrell, Michael P, Banerjee, Shiladitya

“…Collective cell migration in cohesive units is vital for tissue morphogenesis, wound repair, and immune response. While the fundamental driving forces for…”
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Disordered actomyosin networks are sufficient to produce cooperative and telescopic contractility by Linsmeier, Ian, Banerjee, Shiladitya, Oakes, Patrick W., Jung, Wonyeong, Kim, Taeyoon, Murrell, Michael P.

“…While the molecular interactions between individual myosin motors and F-actin are well established, the relationship between F-actin organization and…”
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F-actin architecture determines constraints on myosin thick filament motion by Muresan, Camelia G., Sun, Zachary Gao, Yadav, Vikrant, Tabatabai, A. Pasha, Lanier, Laura, Kim, June Hyung, Kim, Taeyoon, Murrell, Michael P.

“…Active stresses are generated and transmitted throughout diverse F-actin architectures within the cell cytoskeleton, and drive essential behaviors of the cell,…”
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Entropy production rate is maximized in non-contractile actomyosin by Seara, Daniel S., Yadav, Vikrant, Linsmeier, Ian, Tabatabai, A. Pasha, Oakes, Patrick W., Tabei, S. M. Ali, Banerjee, Shiladitya, Murrell, Michael P.

“…The actin cytoskeleton is an active semi-flexible polymer network whose non-equilibrium properties coordinate both stable and contractile behaviors to maintain…”
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Composite branched and linear F-actin maximize myosin-induced membrane shape changes in a biomimetic cell model by Sakamoto, Ryota, Murrell, Michael P.

“…The architecture of the actin cortex determines the generation and transmission of stresses, during key events from cell division to migration. However, its…”
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Spontaneous migration of cellular aggregates from giant keratocytes to running spheroids by Beaune, Grégory, Blanch-Mercader, Carles, Douezan, Stéphane, Dumond, Julien, Gonzalez-Rodriguez, David, Cuvelier, Damien, Ondarçuhu, Thierry, Sens, Pierre, Dufour, Sylvie, Murrell, Michael P., Brochard-Wyart, Françoise

“…Despite extensive knowledge on the mechanisms that drive singlecell migration, those governing the migration of cell clusters, as occurring during embryonic…”
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Data Science in Statistics Curricula: Preparing Students to "Think with Data" by Hardin, J., Hoerl, R., Horton, Nicholas J., Nolan, D., Baumer, B., Hall-Holt, O., Murrell, P., Peng, R., Roback, P., Temple Lang, D., Ward, M. D.

“…A growing number of students are completing undergraduate degrees in statistics and entering the workforce as data analysts. In these positions, they are…”
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Distribution of directional change as a signature of complex dynamics by Burov, Stanislav, Tabei, S. M. Ali, Huynh, Toan, Murrell, Michael P., Philipson, Louis H., Rice, Stuart A., Gardel, Margaret L., Scherer, Norbert F., Dinner, Aaron R.

“…Analyses of random walks traditionally use the mean square displacement (MSD) as an order parameter characterizing dynamics. We show that the distribution of…”
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Dysregulation of TSP2-Rac1-WAVE2 axis in diabetic cells leads to cytoskeletal disorganization, increased cell stiffness, and dysfunction by Xing, Hao, Huang, Yaqing, Kunkemoeller, Britta H., Dahl, Peter J., Muraleetharan, Ohvia, Malvankar, Nikhil S., Murrell, Michael P., Kyriakides, Themis R.

“…Fibroblasts are a major cell population that perform critical functions in the wound healing process. In response to injury, they proliferate and migrate into…”
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Author Correction: Dysregulation of TSP2-Rac1-WAVE2 axis in diabetic cells leads to cytoskeletal disorganization, increased cell stiffness, and dysfunction by Xing, Hao, Huang, Yaqing, Kunkemoeller, Britta H., Dahl, Peter J., Muraleetharan, Ohvia, Malvankar, Nikhil S., Murrell, Michael P., Kyriakides, Themis R.

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How cells flow in the spreading of cellular aggregates by Beaune, Grègory, Stirbat, Tomita Vasilica, Khalifat, Nada, Cochet-Escartin, Olivier, Garcia, Simon, Gurchenkov, Vasily Valèrïèvitch, Murrell, Michael P., Dufour, Sylvie, Cuvelier, Damien, Brochard-Wyart, Françoise

“…Like liquid droplets, cellular aggregates, also called “living droplets,” spread onto adhesive surfaces. When deposited onto fibronectin-coated glass or…”
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Dynamic motions of molecular motors in the actin cytoskeleton by Jung, Wonyeong, Tabatabai, A. Pasha, Thomas, Jacob J., Tabei, S. M. Ali, Murrell, Michael P., Kim, Taeyoon

“…During intracellular transport, cellular cargos, such as organelles, vesicles, and proteins, are transported within cells. Intracellular transport plays an…”
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Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex by Sakamoto, Ryota, Banerjee, Deb Sankar, Yadav, Vikrant, Chen, Sheng, Gardel, Margaret L., Sykes, Cecile, Banerjee, Shiladitya, Murrell, Michael P.

“…The accumulation and transmission of mechanical stresses in the cell cortex and membrane determines the mechanics of cell shape and coordinates essential…”
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Active tension and membrane friction mediate cortical flows and blebbing in a model actomyosin cortex by Sakamoto, R., Murrell, M. P.

“…Blebs, spherical membrane bulges of the cell membrane, are ubiquitous structures observed in various biological phenomena, including apoptosis, cell division,…”
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Author Correction: Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex by Sakamoto, Ryota, Banerjee, Deb Sankar, Yadav, Vikrant, Chen, Sheng, Gardel, Margaret L., Sykes, Cecile, Banerjee, Shiladitya, Murrell, Michael P.

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Laser Speckle Flowmetry Method for Measuring Spatial and Temporal Hemodynamic Alterations Throughout Large Microvascular Networks by MEISNER, JOSHUA K., SUMER, SUNA, MURRELL, KELSEY P., HIGGINS, TIMOTHY J., PRICE, RICHARD J.

“…Please cite this paper as: Meisner JK, Sumer S, Murrell KP, Higgins TJ, Price RJ. Laser speckle flowmetry method for measuring spatial and temporal hemodynamic…”
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