Search Results - "Murray, T K"

Longitudinal changes in EEG power, sleep cycles and behaviour in a tau model of neurodegeneration by Holton, C. M, Hanley, N, Shanks, E, Oxley, P, McCarthy, A, Eastwood, B. J, Murray, T. K, Nickerson, A, Wafford, K. A

“…Abstract Background Disturbed sleep is associated with cognitive decline in neurodegenerative diseases such as Alzheimer’s disease (AD) and frontotemporal…”
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Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease by Colgan, N., Siow, B., O'Callaghan, J.M., Harrison, I.F., Wells, J.A., Holmes, H.E., Ismail, O., Richardson, S., Alexander, D.C., Collins, E.C., Fisher, E.M., Johnson, R., Schwarz, A.J., Ahmed, Z., O'Neill, M.J., Murray, T.K., Zhang, H., Lythgoe, M.F.

“…Increased hyperphosphorylated tau and the formation of intracellular neurofibrillary tangles are associated with the loss of neurons and cognitive decline in…”
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In vivo imaging of tau pathology using multi-parametric quantitative MRI by Wells, J.A., O'Callaghan, J.M., Holmes, H.E., Powell, N.M., Johnson, R.A., Siow, B., Torrealdea, F., Ismail, O., Walker-Samuel, S., Golay, X., Rega, M., Richardson, S., Modat, M., Cardoso, M.J., Ourselin, S., Schwarz, A.J., Ahmed, Z., Murray, T.K., O'Neill, M.J., Collins, E.C., Colgan, N., Lythgoe, M.F.

“…As the number of people diagnosed with Alzheimer's disease (AD) reaches epidemic proportions, there is an urgent need to develop effective treatment strategies…”
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Making Imaginary Roots Real by Murray, Natasha T. K

“…Students in an entry-level algebra class attempt to make sense of the relationship between imaginary zeros and their nonimaginary counterparts…”
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Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment by de Foubert, G., Carney, S.L., Robinson, C.S., Destexhe, E.J., Tomlinson, R., Hicks, C.A., Murray, T.K., Gaillard, J.P., Deville, C., Xhenseval, V., Thomas, C.E., O'Neill, M.J., Zetterström, T.S.C.

“…Recent studies indicate that brain-derived neurotrophic factor (BDNF) may be implicated in the clinical action of antidepressant drugs. Repeated (2–3 weeks)…”
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Mother - Child Mutually Responsive Orientation and Conscience Development: From Toddler to Early School Age by Kochanska, Grazyna, Murray, Kathleen T.

“…We examined whether positive implications of mother-child mutually responsive orientation, demonstrated earlier at toddler and preschool age, extend…”
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Ibutilide by MURRAY, K. T

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In vivo evidence for free radical involvement in the degeneration of rat brain 5‐HT following administration of MDMA (‘ecstasy’) and p‐chloroamphetamine but not the degeneration following fenfluramine by Colado, M I, O'Shea, E, Granados, R, Murray, T K, Green, A R

“…Administration of 3,4‐methylenedioxymethamphetamine (MDMA or ‘ecstasy’) to several species results in a long lasting neurotoxic degeneration of…”
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A study of the neurotoxic effect of MDMA (‘ecstasy’) on 5‐HT neurones in the brains of mothers and neonates following administration of the drug during pregnancy by Colado, M. I., O'Shea, E., Granados, R., Misra, A., Murray, T. K., Green, A. R.

“…It is well established that 3,4‐methylenedioxymethamphetamine (MDMA or ‘ecstasy’) is neurotoxic and produces long term degeneration of cerebral…”
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Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease by O'Callaghan, J., Holmes, H., Powell, N., Wells, J.A., Ismail, O., Harrison, I.F., Siow, B., Johnson, R., Ahmed, Z., Fisher, A., Meftah, S., O'Neill, M.J., Murray, T.K., Collins, E.C., Shmueli, K., Lythgoe, M.F.

“…Alzheimer's disease is connected to a number of other neurodegenerative conditions, known collectively as ‘tauopathies’, by the presence of aggregated tau…”
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Effortful Control in Early Childhood: Continuity and Change, Antecedents, and Implications for Social Development by Kochanska, Grazyna, Murray, Kathleen T, Harlan, Elena T

“…The course, antecedents, and implications for social development of effortful control were examined in this comprehensive longitudinal study. Behavioral…”
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A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066 by Snape, M.F., Misra, A., Murray, T.K., De Souza, R.J., Williams, J.L., Cross, A.J., Green, A.R.

“…The in vitro and in vivo effects of the novel acetylcholinesterase inhibitors donepezil and NXX-066 have been compared to tacrine. Using purified…”
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Activation of Protein Kinase A Modulates Trafficking of the Human Cardiac Sodium Channel in Xenopus Oocytes by Zhou, Jingsong, Yi, Jianxun, Hu, NingNing, George, Alfred L, Murray, Katherine T

“…Voltage-gated Na channels are critical determinants of electrophysiological properties in the heart. Stimulation of β-adrenergic receptors, which activate…”
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The effect of excitotoxic hippocampal lesions on simple and conditional discrimination learning in the rat by Murray, T.K., Ridley, R.M.

“…The effect of excitotoxic lesions of the hippocampus on acquisition and reversal of simple and conditional tasks was investigated using a Y-maze…”
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Stereoselective interactions of the enantiomers of chromanol 293B with human voltage-gated potassium channels by Yang, I C, Scherz, M W, Bahinski, A, Bennett, P B, Murray, K T

“…Selective inhibitors of the slow component of the cardiac delayed rectifier K(+) current, I(Ks), are of interest as novel class III antiarrhythmic agents and…”
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The Development of Self-Regulation in the First Four Years of Life by Kochanska, Grazyna, Coy, Katherine C., Murray, Kathleen T.

“…This study examined longitudinally the development of self-regulation in 108 young children during the first 4 years of life. Children's committed compliance…”
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Oral Erythromycin and the Risk of Sudden Death from Cardiac Causes by Ray, Wayne A, Murray, Katherine T, Meredith, Sarah, Narasimhulu, Sukumar Suguna, Hall, Kathi, Stein, C. Michael

“…Erythromycin is known to prolong cardiac repolarization and has been associated with case reports of torsades de pointes. In this study, the use of oral…”
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Clomethiazole is neuroprotective in models of global and focal cerebral ischemia when infused at doses producing clinically relevant plasma concentrations by Sydserff, S.G, Cross, A.J, Murray, T.K, Jones, J.A, Green, A.R

“…We investigated the neuroprotective effect of infusing various doses of clomethiazole in models of global and focal cerebral ischemia. In a model of global…”
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Functional effects of protein kinase C activation on the human cardiac Na+ channel by MURRAY, K. T, HU, N, DAW, J. R, SHIN, H.-G, WATSON, M. T, MASHBURN, A. B, GEORGE, A. L

“…The cardiac Na+ current plays an important role in determining normal and abnormal impulse propagation in the heart. We have investigated the effects of…”
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ARL 17477, a selective nitric oxide synthase inhibitor, with neuroprotective effects in animal models of global and focal cerebral ischaemia by O’Neill, Michael J., Murray, Tracey K., McCarty, Deborah R., Hicks, Caroline A., Dell, Colin P., Patrick, Kelly E., Ward, Mark A., Osborne, David J., Wiernicki, Todd R., Roman, Carlos R., Lodge, David, Fleisch, Jerome H., Singh, JaiPal

“…In the present studies, we have evaluated the effects of N-[4-(2-{[(3-Chlorophenyl)methyl]amino}ethyl)phenyl]-2-thiophenecarboximidamide dihydrochloride (ARL…”
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