Search Results - "Murray, Karen F."

Neonatal Cholestasis by Lane, Erin, MD, Murray, Karen F., MD

“…Neonatal jaundice is common and usually not concerning when it is secondary to unconjugated hyperbilirubinemia, below the neurotoxic level, and resolves early…”
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Consensus Expert Recommendations for the Diagnosis and Management of Autosomal Recessive Polycystic Kidney Disease: Report of an International Conference by Guay-Woodford, Lisa M., MD, Bissler, John J., MD, Braun, Michael C., MD, Bockenhauer, Detlef, MD, Cadnapaphornchai, Melissa A., MD, Dell, Katherine M., MD, Kerecuk, Larissa, MD, Liebau, Max C., MD, Alonso-Peclet, Maria H., MD, Shneider, Benjamin, MD, Emre, Sukru, MD, Heller, Theo, MD, Kamath, Binita M., MD, Murray, Karen F., MD, Moise, Kenneth, MD, Eichenwald, Eric E., MD, Evans, Jacquelyn, MD, Keller, Roberta L., MD, Wilkins-Haug, Louise, MD, Bergmann, Carsten, MD, Gunay-Aygun, Meral, MD, Hooper, Stephen R., PhD, Hardy, Kristina K., PhD, Hartung, Erum A., MD, Streisand, Randi, PhD, Perrone, Ronald, MD, Moxey-Mims, Marva, MD

“…Autosomal recessive polycystic kidney disease (ARPKD; MIM 263200) is a severe, typically early onset form of cystic disease that primarily involves the kidneys…”
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Alanine Aminotransferase and Gamma‐Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis by Newton, Kimberly P., Lavine, Joel E., Wilson, Laura, Behling, Cynthia, Vos, Miriam B., Molleston, Jean P., Rosenthal, Philip, Miloh, Tamir, Fishbein, Mark H., Jain, Ajay K., Murray, Karen F., Schwimmer, Jeffrey B.

“…Background and Aims Predictive, noninvasive tools are needed to monitor key features of nonalcoholic fatty liver disease (NAFLD) in children that relate to…”
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Histological Abnormalities in Children with Nonalcoholic Fatty Liver Disease and Normal or Mildly Elevated Alanine Aminotransferase Levels by Molleston, Jean P., MD, Schwimmer, Jeffrey B., MD, Yates, Katherine P., MD, Murray, Karen F., MD, Cummings, Oscar W., MD, Lavine, Joel E., MD, PhD, Brunt, Elizabeth M., MD, Scheimann, Ann O., MD, Unalp-Arida, Aynur, MD, PhD

“…Objective To investigate the histological spectrum of nonalcoholic fatty liver disease (NAFLD) in children with normal, mildly elevated (26-50 U/L boys, 23-44…”
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Acute liver failure in children: The first 348 patients in the pediatric acute liver failure study group by Squires, Robert H., Shneider, Benjamin L., Bucuvalas, John, Alonso, Estella, Sokol, Ronald J., Narkewicz, Michael R., Dhawan, Anil, Rosenthal, Philip, Rodriguez-Baez, Norberto, Murray, Karen F., Horslen, Simon, Martin, Martin G., Lopez, M. James, Soriano, Humberto, McGuire, Brendan M., Jonas, Maureen M., Yazigi, Nada, Shepherd, Ross W., Schwarz, Kathleen, Lobritto, Steven, Thomas, Daniel W., Lavine, Joel E., Karpen, Saul, Ng, Vicky, Kelly, Deirdre, Simonds, Nancy, Hynan, Linda S.

“…To determine short-term outcome for children with acute liver failure (ALF) as it relates to cause, clinical status, and patient demographics and to determine…”
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Pattern of Diagnostic Evaluation for the Causes of Pediatric Acute Liver Failure: An Opportunity for Quality Improvement by Narkewicz, Michael R., MD, Dell Olio, Dominic, MD, Karpen, Saul J., MD, PhD, Murray, Karen F., MD, Schwarz, Kathy, MD, Yazigi, Nada, MD, Zhang, Song, MS, Belle, Steven H., PhD, MScHyg, Squires, Robert H., MD

“…Objective To describe the frequency of diagnostic testing for the 4 most common causes of pediatric acute liver failure (PALF) (drugs, metabolic disease,…”
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Impact of progressive familial intrahepatic cholestasis on caregivers: caregiver-reported outcomes from the multinational PICTURE study by Mighiu, Claudia, O'Hara, Sonia, Ferri Grazzi, Enrico, Murray, Karen F, Schattenberg, Jörn M, Ventura, Emily, Karakaidos, Melanie, Taylor, Alison, Brrang, Harpreet, Dhawan, Anil, Willemse, Jose, Finnegan, Alan

“…Progressive familial intrahepatic cholestasis (PFIC) is a spectrum of rare genetic diseases characterized by inadequate bile secretion that requires…”
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Drug‐related Hepatotoxicity and Acute Liver Failure by Murray, Karen F, Hadzic, Nedim, Wirth, Stefan, Bassett, Mikelle, Kelly, Deirdre

“…ABSTRACT Drug‐induced acute liver failure (ALF) accounts for approximately 20% of ALF in children and a higher percentage of ALF in adults. Although most…”
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Initial assessment of the infant with neonatal cholestasis-Is this biliary atresia? by Shneider, Benjamin L, Moore, Jeff, Kerkar, Nanda, Magee, John C, Ye, Wen, Karpen, Saul J, Kamath, Binita M, Molleston, Jean P, Bezerra, Jorge A, Murray, Karen F, Loomes, Kathleen M, Whitington, Peter F, Rosenthal, Philip, Squires, Robert H, Guthery, Stephen L, Arnon, Ronen, Schwarz, Kathleen B, Turmelle, Yumirle P, Sherker, Averell H, Sokol, Ronald J

“…Optimizing outcome in biliary atresia (BA) requires timely diagnosis. Cholestasis is a presenting feature of BA, as well as other diagnoses (Non-BA)…”
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Medical Status of 219 Children with Biliary Atresia Surviving Long-Term with Their Native Livers: Results from a North American Multicenter Consortium by Ng, Vicky Lee, MD, Haber, Barbara H., MD, Magee, John C., MD, Miethke, Alexander, MD, Murray, Karen F., MD, Michail, Sonia, MD, Karpen, Saul J., MD, Kerkar, Nanda, MD, Molleston, Jean P., MD, Romero, Rene, MD, Rosenthal, Philip, MD, Schwarz, Kathleen B., MD, Shneider, Benjamin L., MD, Turmelle, Yumirle P., MD, Alonso, Estella M., MD, Sherker, Averell H., MD, Sokol, Ronald J., MD

“…Objectives To examine the medical status of children with biliary atresia (BA) with their native livers after hepato- portoenterostomy (HPE) surgery. Study…”
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Pegylated interferon for chronic hepatitis C in children affects growth and body composition: Results from the pediatric study of hepatitis C (PEDS-C) trial by Jonas, Maureen M., Balistreri, William, Gonzalez-Peralta, Regino P., Haber, Barbara, Lobritto, Steven, Mohan, Parvathi, Molleston, Jean P., Murray, Karen F., Narkewicz, Michael R., Rosenthal, Philip, Schwarz, Kathleen B., Barton, Bruce A., Shepherd, John A., Mitchell, Paul D., Duggan, Christopher

“…Weight loss and changes in growth are noted in children treated with interferon alpha (IFN‐α). The aim of this study was to prospectively determine changes in…”
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Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Study by Kamath, Binita M., Ye, Wen, Goodrich, Nathan P., Loomes, Kathleen M., Romero, Rene, Heubi, James E., Leung, Daniel H., Spinner, Nancy B., Piccoli, David A., Alonso, Estella M., Guthery, Stephen L., Karpen, Saul J., Mack, Cara L., Molleston, Jean P., Murray, Karen F., Rosenthal, Philip, Squires, James E., Teckman, Jeffrey, Wang, Kasper S., Thompson, Richard, Magee, John C., Sokol, Ronald J.

“…Alagille syndrome (ALGS) is an autosomal dominant multisystem disorder with cholestasis as a defining clinical feature. We sought to characterize hepatic…”
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Placebo‐Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome by Shneider, Benjamin L., Spino, Cathie, Kamath, Binita M., Magee, John C., Bass, Lee M., Setchell, Kenneth D., Miethke, Alexander, Molleston, Jean P., Mack, Cara L., Squires, Robert H., Murray, Karen F., Loomes, Kathleen M., Rosenthal, Philip, Karpen, Saul J., Leung, Daniel H., Guthery, Stephen L., Thomas, Danny, Sherker, Averell H., Sokol, Ronald J.

“…Medically refractory, severe, cholestasis‐induced pruritus in Alagille syndrome may be improved by surgical interruption of the enterohepatic circulation. This…”
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Pathology of chronic hepatitis C in children: Liver biopsy findings in the Peds‐C Trial by Goodman, Zachary D., Makhlouf, Hala R., Liu, Lea, Balistreri, William, Gonzalez‐Peralta, Regino P., Haber, Barbara, Jonas, Maureen M., Mohan, Parvathi, Molleston, Jean P., Murray, Karen F., Narkewicz, Michael R., Rosenthal, Philip, Smith, Lesley J., Robuck, Patricia R., Schwarz, Kathleen B.

“…There is relatively little information in the literature on the histopathology of chronic hepatitis C in children. The Peds‐C Trial, designed to test the…”
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Baseline Ultrasound and Clinical Correlates in Children with Cystic Fibrosis by Leung, Daniel H., MD, Ye, Wen, PhD, Molleston, Jean P., MD, Weymann, Alexander, MD, Ling, Simon, MD, Paranjape, Shruti M., MD, Romero, Rene, MD, Schwarzenberg, Sara Jane, MD, Palermo, Joseph, MD, Alonso, Estella M., MD, Murray, Karen F., MD, Marshall, Bruce C., MD, Sherker, Averell H., MD, Siegel, Marilyn J., MD, Krishnamurthy, Rajesh, MD, Harned, Roger, MD, Karmazyn, Boaz, MD, Magee, John C., MD, Narkewicz, Michael R., MD

“…Objective To investigate the relationship between abdominal ultrasound findings and demographic, historical, and clinical features in children with cystic…”
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Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis by Malyukova, Irina, Murray, Karen F, Zhu, Chengru, Boedeker, Edgar, Kane, Anne, Patterson, Kathleen, Peterson, Jeffrey R, Donowitz, Mark, Kovbasnjuk, Olga

“…Shiga toxin 1 and 2 production is a cardinal virulence trait of enterohemorrhagic Escherichia coli infection that causes a spectrum of intestinal and systemic…”
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Children with Chronic Hepatitis B in the United States and Canada by Schwarz, Kathleen B., MD, Cloonan, Yona Keich, PhD, Ling, Simon C., MD, Murray, Karen F., MD, Rodriguez-Baez, Norberto, MD, Schwarzenberg, Sarah Jane, MD, Teckman, Jeffrey, MD, Ganova-Raeva, Lilia, PhD, Rosenthal, Philip, MD

“…Objectives To test the hypothesis that children with chronic hepatitis B living in the US and Canada would have international origins and characteristic…”
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Quality of Life and Its Determinants in a Multicenter Cohort of Children with Alagille Syndrome by Kamath, Binita M., MBBChir, Chen, Zhen, MS, Romero, Rene, MD, Fredericks, Emily M., PhD, Alonso, Estella M., MD, Arnon, Ronen, MD, Heubi, James, MD, Hertel, Paula M., MD, Karpen, Saul J., MD, PhD, Loomes, Kathleen M., MD, Murray, Karen F., MD, Rosenthal, Philip, MD, Schwarz, Kathleen B., MD, Subbarao, Girish, MD, Teckman, Jeffrey H., MD, Turmelle, Yumirle P., MD, Wang, Kasper S., MD, Sherker, Averell H., MD, Sokol, Ronald J., MD, Magee, John C., MD

“…Objectives To assess health-related quality of life (HRQOL) in children with Alagille syndrome (ALGS) in comparison with healthy and other liver disease…”
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Highly multiplexed 2-dimensional imaging mass cytometry analysis of HBV-infected liver by Traum, Daniel, Wang, Yue J, Schwarz, Kathleen B, Schug, Jonathan, Wong, David Kh, Janssen, Harry LA, Terrault, Norah A, Khalili, Mandana, Wahed, Abdus S, Murray, Karen F, Rosenthal, Phillip, Ling, Simon C, Rodriguez-Baez, Norberto, Sterling, Richard K, Lau, Daryl Ty, Block, Timothy M, Feldman, Michael D, Furth, Elizabeth E, Lee, William M, Kleiner, David E, Lok, Anna S, Kaestner, Klaus H, Chang, Kyong-Mi

“…Studies of human hepatitis B virus (HBV) immune pathogenesis are hampered by limited access to liver tissues and technologies for detailed analyses. Here,…”
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Nonfasted Liver Stiffness Correlates with Liver Disease Parameters and Portal Hypertension in Pediatric Cholestatic Liver Disease by Shneider, Benjamin L., Goodrich, Nathan P., Ye, Wen, Sawyers, Cindy, Molleston, Jean P., Merion, Robert M., Leung, Daniel H., Karpen, Saul J., Kamath, Binita M., Cavallo, Laurel, Wang, Kasper, Teckman, Jeffrey H., Squires, James E., Sundaram, Shikha S., Rosenthal, Philip, Romero, Rene, Murray, Karen F., Loomes, Kathleen M., Jensen, M. Kyle, Bezerra, Jorge A., Bass, Lee M., Sokol, Ronald J., Magee, John C.

“…Elastographic measurement of liver stiffness is of growing importance in the assessment of liver disease. Pediatric experiences with this technique are…”
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