Search Results - "Murray, J.C."

A Population-Based Study of Effects of Genetic Loci on Orofacial Clefts by Moreno Uribe, L.M., Fomina, T., Munger, R.G., Romitti, P.A., Jenkins, M.M., Gjessing, H.K., Gjerdevik, M., Christensen, K., Wilcox, A.J., Murray, J.C., Lie, R.T., Wehby, G.L.

“…Prior genome-wide association studies for oral clefts have focused on clinic-based samples with unclear generalizability. Prior samples were also small for…”
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Genome-wide Gene-by-Sex Interaction Studies Identify Novel Nonsyndromic Orofacial Clefts Risk Locus by Awotoye, W., Comnick, C., Pendleton, C., Zeng, E., Alade, A., Mossey, P.A., Gowans, L.J.J., Eshete, M.A., Adeyemo, W.L., Naicker, T., Adeleke, C., Busch, T., Li, M., Petrin, A., Olotu, J., Hassan, M., Pape, J., Miller, S.E., Donkor, P., Anand, D., Lachke, S.A., Marazita, M.L., Adeyemo, A.A., Murray, J.C., Albokhari, D., Sobreira, N., Butali, A.

“…Risk loci identified through genome-wide association studies have explained about 25% of the phenotypic variations in nonsyndromic orofacial clefts (nsOFCs) on…”
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Association Studies and Direct DNA Sequencing Implicate Genetic Susceptibility Loci in the Etiology of Nonsyndromic Orofacial Clefts in Sub-Saharan African Populations by Gowans, L.J.J., Adeyemo, W.L., Eshete, M., Mossey, P.A., Busch, T., Aregbesola, B., Donkor, P., Arthur, F.K.N., Bello, S.A., Martinez, A., Li, M., Augustine-Akpan, E.A., Deressa, W., Twumasi, P., Olutayo, J., Deribew, M., Agbenorku, P., Oti, A.A., Braimah, R., Plange-Rhule, G., Gesses, M., Obiri-Yeboah, S., Oseni, G.O., Olaitan, P.B., Abdur-Rahman, L., Abate, F., Hailu, T., Gravem, P., Ogunlewe, M.O., Buxó, C.J., Marazita, M.L., Adeyemo, A.A., Murray, J.C., Butali, A.

“…Orofacial clefts (OFCs) are congenital dysmorphologies of the human face and oral cavity, with a global incidence of 1 per 700 live births. These anomalies…”
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Genome-wide Association Scan for Childhood Caries Implicates Novel Genes by Shaffer, J.R., Wang, X., Feingold, E., Lee, M., Begum, F., Weeks, D.E., Cuenco, K.T., Barmada, M.M., Wendell, S.K., Crosslin, D.R., Laurie, C.C., Doheny, K.F., Pugh, E.W., Zhang, Q., Feenstra, B., Geller, F., Boyd, H.A., Zhang, H., Melbye, M., Murray, J.C., Weyant, R.J., Crout, R., McNeil, D.W., Levy, S.M., Slayton, R.L., Willing, M.C., Broffitt, B., Vieira, A.R., Marazita, M.L.

“…Dental caries is the most common chronic disease in children and a major public health concern due to its increasing incidence, serious health and social…”
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IRF6 mutation screening in non-syndromic orofacial clefting: analysis of 1521 families by Leslie, E.J., Koboldt, D.C., Kang, C.J., Ma, L., Hecht, J.T., Wehby, G.L., Christensen, K., Czeizel, A.E., Deleyiannis, F.W.-B., Fulton, R.S., Wilson, R.K., Beaty, T.H., Schutte, B.C., Murray, J.C., Marazita, M.L.

“…Van der Woude syndrome (VWS) is an autosomal dominant malformation syndrome characterized by orofacial clefting (OFC) and lower lip pits. The clinical…”
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MSX1, PAX9, and TGFA Contribute to Tooth Agenesis in Humans by Vieira, A.R., Meira, R., Modesto, A., Murray, J.C.

“…In this study, we sought to determine the association between tooth agenesis and DNA sequence variation in the genes MSX1 and PAX9 in an ethnically diverse…”
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Genetic Studies in the Nigerian Population Implicate an MSX1 Mutation in Complex Oral Facial Clefting Disorders by Butali, A., Mossey, P.A., Adeyemo, W.L., Jezewski, P.A., Onwuamah, C.K., Ogunlewe, M.O., Ugboko, V.I., Adejuyigbe, O., Adigun, A.I., Abdur-Rahman, L.O., Onah, I.I., Audu, R.A., Idigbe, E.O., Mansilla, M.A., Dragan, E.A., Petrin, A.L., Bullard, S.A., Uduezue, A.O., Akpata, O., Osaguona, A.O., Olasoji, H.O., Ligali, T.O., Kejeh, B.M., Iseh, K.R., Olaitan, P.B., Adebola, A.R., Efunkoya, E., Adesina, O.A., Oluwatosin, O.M., Murray, J.C.

“…Background Orofacial clefts are the most common malformations of the head and neck, with a worldwide prevalence of 1 in 700 births. They are commonly divided…”
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MSX1 and TGFB3 Contribute to Clefting in South America by Vieira, A.R., Orioli, I.M., Castilla, E.E., Cooper, M.E., Marazita, M.L., Murray, J.C.

“…MSX1 and TGFB3 have been proposed as genes in which mutations may contribute to non-syndromic forms of oral clefts; however, an interaction between these genes…”
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Three Field Breast Treatment With Block or Multi-Leaf Collimators (MLCs) With 52 and 120 Leaves by Lee, S, Murray, J.C, Guo, P, Luo, C, Harrington, J.C

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A genome-wide linkage scan for cleft lip and cleft palate identifies a novel locus on 8p11-23 by Riley, B.M., Schultz, R.E., Cooper, M.E., Goldstein-McHenry, T., Daack-Hirsch, S., Lee, K.T., Dragan, E., Vieira, A.R., Lidral, A.C., Marazita, M.L., Murray, J.C.

“…Isolated or nonsyndromic cleft lip and palate (NS CLP) is a complex disorder resulting from multiple genetic and environmental factors. NS CLP has a birth…”
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Targeted scan of fifteen regions for nonsyndromic cleft lip and palate in Filipino families by Schultz, R.E., Cooper, M.E., Daack-Hirsch, S., Shi, M., Nepomucena, B., Graf, K.A., O'Brien, E.K., O'Brien, S.E., Marazita, M.L., Murray, J.C.

“…Cleft lip with or without cleft palate (CL/P) is a congenital anomaly with variable birth prevalence based on geographic origins, with the highest rates…”
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Mutations in PITX2 may contribute to cases of omphalocele and VATER-like syndromes by Katz, L.A., Schultz, R.E., Semina, E.V., Torfs, C.P., Krahn, K.N., Murray, J.C.

“…Omphalocele is a congenital anomaly with substantial morbidity. Rieger syndrome, an autosomal dominant disorder, is characterized by craniofacial abnormalities…”
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Puroindoline genes introduced into durum wheat reduce milling energy and change milling behavior similar to soft common wheats by Heinze, K., Kiszonas, A.M., Murray, J.C., Morris, C.F., Lullien-Pellerin, V.

“…Grain physical characteristics and milling behavior of a durum wheat line in which both wild-type puroindoline genes were translocated and stabilized after…”
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Antagonistic Regulation of Dlx2 Expression by PITX2 and Msx2: Implications for Tooth Development by Green, P D, Hjalt, T A, Kirk, D E, Sutherland, L B, Thomas, B L, Sharpe, P T, Snead, M L, Murray, J C, Russo, A F, Amendt, B A

“…The transcriptional mechanisms underlying tooth development are only beginning to be understood. Pitx2, a bicoid-like homeodomain transcription factor, is the…”
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Re-Evaluating Surgery and Re-Irradiation for Locally Recurrent Pediatric Ependymoma — a Multi-Institutional Study by Mak, D.Y., Laperriere, N.J., Ramaswamy, V., Bouffet, E., Murray, J.C., McNall-Knapp, R., Bielamowicz, K., Paulino, A.C., Zaky, W., McGovern, S.L., Okcu, F., Tabori, U., Dirks, P.B., Taylor, M.D., Tsang, D.S.C., Bavle, A.

“…The goal of this study was to evaluate extent of surgical resection, and timing and volume of re-irradiation, on survival for children with locally recurrent…”
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Confirming genes influencing risk to cleft lip with/without cleft palate in a case–parent trio study by Beaty, T. H., Taub, M. A., Scott, A. F., Murray, J. C., Marazita, M. L., Schwender, H., Parker, M. M., Hetmanski, J. B., Balakrishnan, P., Mansilla, M. A., Mangold, E., Ludwig, K. U., Noethen, M. M., Rubini, M., Elcioglu, N., Ruczinski, I.

“…A collection of 1,108 case–parent trios ascertained through an isolated, nonsyndromic cleft lip with or without cleft palate (CL/P) was used to replicate the…”
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Disrupted IRF6-NME1/2 Complexes as a Cause of Cleft Lip/Palate by Parada-Sanchez, M.T., Chu, E.Y., Cox, L.L., Undurty, S.S., Standley, J.M., Murray, J.C., Cox, T.C.

“…Mutations and common polymorphisms in interferon regulatory factor 6 (IRF6) are associated with both syndromic and nonsyndromic forms of cleft lip/palate…”
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Human lung microvessel endothelial cells: isolation, culture, and characterization by Hewett, P W, Murray, J C

“…The pulmonary vasculature is of great physiological/pathological significance. We have isolated and cultured microvessel endothelial cells (HuLEC) from lung…”
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PI(3) kinase is associated with a mechanism of immunoresistance in breast and prostate cancer by Crane, C A, Panner, A, Murray, J C, Wilson, S P, Xu, H, Chen, L, Simko, J P, Waldman, F M, Pieper, R O, Parsa, A T

“…Immune escape describes a critical event whereby tumor cells adopt an immunoresistant phenotype to escape adaptive surveillance. We show that expression of a…”
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Global Oral Health Inequalities: Challenges in the Prevention and Management of Orofacial Clefts and Potential Solutions by Mossey, P.A., Shaw, W.C., Munger, R.G., Murray, J.C., Murthy, J., Little, J.

“…The birth prevalence of orofacial clefts, one of the most common congenital anomalies, is approximately one in 700 live births, but varies with geography,…”
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