Search Results - "Murray, J."

Macrophage Polarization by Murray, Peter J

“…Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are…”
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Advancing the use of genome-wide association studies for drug repurposing by Reay, William R., Cairns, Murray J.

“…Genome-wide association studies (GWAS) have revealed important biological insights into complex diseases, which are broadly expected to lead to the…”
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Super-enhancers in transcriptional regulation and genome organization by Wang, Xi, Cairns, Murray J, Yan, Jian

“…Gene expression is precisely controlled in a stage and cell-type-specific manner, largely through the interaction between cis-regulatory elements and their…”
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The Global Burden of Disease Study at 30 years by Murray, Christopher J. L.

“…The Global Burden of Disease Study (GBD) began 30 years ago with the goal of providing timely, valid and relevant assessments of critical health outcomes. Over…”
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Tryptophan and indole metabolism in immune regulation by Fiore, Alessandra, Murray, Peter J

“…•Tryptophan follows three metabolic fates: incorporation into proteins, production of indoles, and breakdown into kynurenine.•IDO1 is an endogenous mechanism…”
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MicroRNA and Posttranscriptional Dysregulation in Psychiatry by Geaghan, Michael, Cairns, Murray J

“…Abstract Psychiatric syndromes, including schizophrenia, mood disorders, and autism spectrum disorders, are characterized by a complex range of symptoms,…”
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The JAK-STAT Signaling Pathway: Input and Output Integration by Murray, Peter J

“…Universal and essential to cytokine receptor signaling, the JAK-STAT pathway is one of the best understood signal transduction cascades. Almost 40 cytokine…”
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Protective and pathogenic functions of macrophage subsets by Murray, Peter J, Wynn, Thomas A

“…Key Points Macrophages are highly heterogenous cells that can rapidly change their function in response to local microenvironmental signals. Although distinct…”
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Opinion: Cloud-phase climate feedback and the importance of ice-nucleating particles by Murray, Benjamin J, Carslaw, Kenneth S, Field, Paul R

“…Shallow clouds covering vast areas of the world's middle- and high-latitude oceans play a key role in dampening the global temperature rise associated with…”
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On macrophage diversity and inflammatory metabolic timers by Murray, Peter J.

“…Key papers were published in 2019 that solidify the notion that macrophage gene expression is remarkably diverse; single-cell sequencing combined with new…”
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Bisphosphonates for Osteoporosis by Favus, Murray J

“…A 67-year-old woman is referred by her primary care physician for treatment of osteoporosis and progressive bone loss. Oral bisphosphonate therapy is…”
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Obstacles and opportunities for understanding macrophage polarization by Murray, Peter J., Wynn, Thomas A.

“…Review on new issues concerning macrophage polarization and the impact of polarization and categorization of macrophage subsets on immunology. Macrophages are…”
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The Potential Future of the COVID-19 Pandemic: Will SARS-CoV-2 Become a Recurrent Seasonal Infection? by Murray, Christopher J. L, Piot, Peter

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Macrophages and cancer: from mechanisms to therapeutic implications by Ostuni, Renato, Kratochvill, Franz, Murray, Peter J, Natoli, Gioacchino

“…Highlights • Circulating monocytes are the primary source of TAMs in many tumors. • TAM properties are shaped by tissue- and tumor-specific microenvironmental…”
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MicroRNA: Small RNA mediators of the brains genomic response to environmental stress by Hollins, Sharon L, Cairns, Murray J

“…The developmental processes that establish the synaptic architecture of the brain while retaining capacity for activity-dependent remodeling, are complex and…”
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US Health Care Spending by Payer and Health Condition, 1996-2016 by Dieleman, Joseph L, Cao, Jackie, Chapin, Abby, Chen, Carina, Li, Zhiyin, Liu, Angela, Horst, Cody, Kaldjian, Alexander, Matyasz, Taylor, Scott, Kirstin Woody, Bui, Anthony L, Campbell, Madeline, Duber, Herbert C, Dunn, Abe C, Flaxman, Abraham D, Fitzmaurice, Christina, Naghavi, Mohsen, Sadat, Nafis, Shieh, Peter, Squires, Ellen, Yeung, Kai, Murray, Christopher J. L

“…IMPORTANCE: US health care spending has continued to increase and now accounts for 18% of the US economy, although little is known about how spending on each…”
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Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010 by Whiteford, Harvey A, Prof, Degenhardt, Louisa, Prof, Rehm, Jürgen, Prof, Baxter, Amanda J, MPH, Ferrari, Alize J, BPsySc, Erskine, Holly E, BPsySc, Charlson, Fiona J, MPH, Norman, Rosana E, PhD, Flaxman, Abraham D, PhD, Johns, Nicole, BA, Burstein, Roy, BA, Murray, Christopher JL, Prof, Vos, Theo, Prof

“…Summary Background We used data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) to estimate the burden of disease…”
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Increased educational attainment and its effect on child mortality in 175 countries between 1970 and 2009: a systematic analysis by Gakidou, Emmanuela, Dr, Cowling, Krycia, BS, Lozano, Rafael, Prof, Murray, Christopher JL, Prof

“…Summary Background In addition to the inherent importance of education and its essential role in economic growth, education and health are strongly related. We…”
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Understanding Local Macrophage Phenotypes In Disease: Modulating macrophage function to treat cancer by Bronte, Vincenzo, Murray, Peter J

“…Recent studies have suggested that manipulating the tumor-associated macrophage phenotype is a valid therapeutic approach in cancer. In turn, these studies…”
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Drone-Aided Healthcare Services for Patients with Chronic Diseases in Rural Areas by Kim, Seon Jin, Lim, Gino J., Cho, Jaeyoung, Côté, Murray J.

“…This paper addresses the drone-aided delivery and pickup planning of medication and test kits for patients with chronic diseases who are required to visit…”
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