Search Results - "Murray, Elisabeth A."
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The Orbitofrontal Oracle: Cortical Mechanisms for the Prediction and Evaluation of Specific Behavioral Outcomes
Published in Neuron (Cambridge, Mass.) (17-12-2014)“…The orbitofrontal cortex (OFC) has long been associated with the flexible control of behavior and concepts such as behavioral inhibition, self-control, and…”
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Specializations for reward-guided decision-making in the primate ventral prefrontal cortex
Published in Nature reviews. Neuroscience (01-07-2018)“…The estimated values of choices, and therefore decision-making based on those values, are influenced by both the chance that the chosen items or goods can be…”
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Effects of Amygdala Lesions on Reward-Value Coding in Orbital and Medial Prefrontal Cortex
Published in Neuron (Cambridge, Mass.) (18-12-2013)“…We examined the contribution of the amygdala to value signals within orbital prefrontal cortex (OFC) and medial prefrontal cortex (MFC). On each trial, monkeys…”
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Specialized Representations of Value in the Orbital and Ventrolateral Prefrontal Cortex: Desirability versus Availability of Outcomes
Published in Neuron (Cambridge, Mass.) (30-08-2017)“…Advantageous foraging choices benefit from an estimation of two aspects of a resource’s value: its current desirability and availability. Both orbitofrontal…”
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Amygdala and Ventral Striatum Make Distinct Contributions to Reinforcement Learning
Published in Neuron (Cambridge, Mass.) (19-10-2016)“…Reinforcement learning (RL) theories posit that dopaminergic signals are integrated within the striatum to associate choices with outcomes. Often overlooked is…”
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Prefrontal mechanisms of behavioral flexibility, emotion regulation and value updating
Published in Nature neuroscience (01-08-2013)“…Existing data are consistent with a role for the orbitofrontal cortex (OFC) either in regulating emotion and enhancing behavioral flexibility or in updating…”
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The anterior cingulate cortex is necessary for forming prosocial preferences from vicarious reinforcement in monkeys
Published in PLoS biology (12-06-2020)“…A key feature of most social relationships is that we like seeing good things happen to others. Research has implicated the anterior cingulate cortex (ACC) in…”
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Localization of Dysfunction in Major Depressive Disorder: Prefrontal Cortex and Amygdala
Published in Biological psychiatry (1969) (15-06-2011)“…Despite considerable effort, the localization of dysfunction in major depressive disorder (MDD) remains poorly understood. We present a hypothesis about its…”
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Visual perception and memory : A new view of medial temporal lobe function in primates and rodents
Published in Annual review of neuroscience (01-01-2007)“…The prevailing view of medial temporal lobe (MTL) function has two principal elements: first, that the MTL subserves memory but not perception, and second,…”
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Balkanizing the primate orbitofrontal cortex: distinct subregions for comparing and contrasting values
Published in Annals of the New York Academy of Sciences (01-12-2011)“…The primate orbitofrontal cortex (OFC) is often treated as a single entity, but architectonic and connectional neuroanatomy indicate that it has…”
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Amygdala lesions eliminate viewing preferences for faces in rhesus monkeys
Published in Proceedings of the National Academy of Sciences - PNAS (31-07-2018)“…In free-viewing experiments, primates orient preferentially toward faces and face-like stimuli. To investigate the neural basis of this behavior, we measured…”
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Orbitofrontal Cortex and Amygdala Contributions to Affect and Action in Primates
Published in Annals of the New York Academy of Sciences (01-12-2007)“…: The amygdala and orbitofrontal cortex (OFC) work together as part of the neural circuitry guiding goal‐directed behavior. This chapter explores the way in…”
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The Motivational Role of the Ventral Striatum and Amygdala in Learning From Gains and Losses
Published in Behavioral neuroscience (01-08-2023)“…The ventral striatum (VS) and amygdala are two structures often implicated as essential structures for learning. The literature addressing the contribution of…”
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Amygdala Contributions to Stimulus-Reward Encoding in the Macaque Medial and Orbital Frontal Cortex during Learning
Published in The Journal of neuroscience (22-02-2017)“…Orbitofrontal cortex (OFC), medial frontal cortex (MFC), and amygdala mediate stimulus-reward learning, but the mechanisms through which they interact are…”
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Amygdala and Orbitofrontal Cortex Lesions Differentially Influence Choices during Object Reversal Learning
Published in The Journal of neuroscience (13-08-2008)“…In nonhuman primates, interaction between the orbitofrontal cortex (OFC) and the amygdala (AMG) has been seen as critical for learning and subsequently…”
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The amygdala is not necessary for the familiarity aspect of recognition memory
Published in Nature communications (07-12-2023)“…Dual-process accounts of item recognition posit two memory processes: slow but detailed recollection, and quick but vague familiarity. It has been proposed,…”
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role for primate subgenual cingulate cortex in sustaining autonomic arousal
Published in Proceedings of the National Academy of Sciences - PNAS (08-04-2014)“…The subgenual anterior cingulate cortex (subgenual ACC) plays an important role in regulating emotion, and degeneration in this area correlates with depressed…”
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Differential effects of amygdala, orbital prefrontal cortex, and prelimbic cortex lesions on goal-directed behavior in rhesus macaques
Published in The Journal of neuroscience (20-02-2013)“…We assessed the involvement of the orbital prefrontal cortex (PFo), the prelimbic region of the medial prefrontal cortex (PL), and the amygdala in…”
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No evidence that monkeys attribute mental states to animated shapes in the Heider–Simmel videos
Published in Scientific reports (04-02-2021)“…Human Theory of Mind (ToM) is so automatic and pervasive that we spontaneously attribute mental states to animated abstract shapes, as evidenced by the classic…”
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Specialized areas for value updating and goal selection in the primate orbitofrontal cortex
Published in eLife (17-12-2015)“…The macaque orbitofrontal cortex (OFC) is essential for selecting goals based on current, updated values of expected reward outcomes. As monkeys consume a…”
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