Search Results - "Murray, Daniel D."

Associations of functional human leucocyte antigen class I groups with HIV viral load in a heterogeneous cohort by Zucco, Adrian G, Bennedbæk, Marc, Ekenberg, Christina, Gabrielaite, Migle, Leung, Preston, Polizzotto, Mark N, Kan, Virginia, Murray, Daniel D, Lundgren, Jens D, MacPherson, Cameron R

“…Human leucocyte antigen (HLA) class I alleles are the main host genetic factors involved in controlling HIV-1 viral load (VL). Nevertheless, HLA diversity has…”
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Metabolic Potential of the Gut Microbiome Is Significantly Impacted by Conditioning Regimen in Allogeneic Hematopoietic Stem Cell Transplantation Recipients by Jørgensen, Mette, Nørgaard, Jens C., Ilett, Emma E., Marandi, Ramtin Z., Noguera-Julian, Marc, Paredes, Roger, Murray, Daniel D., Lundgren, Jens, MacPherson, Cameron Ross, Sengeløv, Henrik

“…Allogeneic hematopoietic stem cell transplantation (aHSCT) is a putative curative treatment for malignant hematologic disorders. During transplantation, the…”
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Role of Inflammatory Biomarkers in the Prevalence and Incidence of Hypertension Among HIV-Positive Participants in the START Trial by Ghazi, Lama, Baker, Jason V, Sharma, Shweta, Jain, Mamta K, Palfreeman, Adrian, Necsoi, Coca, Murray, Daniel D, Neaton, James D, Drawz, Paul E

“…Abstract BACKGROUND The association between hypertension (HTN) and inflammatory biomarkers (interleukin-6 [IL-6] and high-sensitivity C-reactive protein…”
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Added Value of Reanalysis of Whole Exome- and Whole Genome Sequencing Data From Patients Suspected of Primary Immune Deficiency Using an Extended Gene Panel and Structural Variation Calling by Mørup, Sara Bohnstedt, Nazaryan-Petersen, Lusine, Gabrielaite, Migle, Reekie, Joanne, Marquart, Hanne V., Hartling, Hans Jakob, Marvig, Rasmus L., Katzenstein, Terese L., Masmas, Tania N., Lundgren, Jens, Murray, Daniel D., Helleberg, Marie, Borgwardt, Line

“…Background Knowledge of the genetic variation underlying Primary Immune Deficiency (PID) is increasing. Reanalysis of genome-wide sequencing data from…”
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The association between single-nucleotide polymorphisms within type 1 interferon pathway genes and human immunodeficiency virus type 1 viral load in antiretroviral-naïve participants by Mørup, Sara Bohnstedt, Leung, Preston, Reilly, Cavan, Sherman, Brad T, Chang, Weizhong, Milojevic, Maja, Milinkovic, Ana, Liappis, Angelike, Borgwardt, Line, Petoumenos, Kathy, Paredes, Roger, Mistry, Shweta S, MacPherson, Cameron R, Lundgren, Jens, Helleberg, Marie, Reekie, Joanne, Murray, Daniel D

“…Human genetic contribution to HIV progression remains inadequately explained. The type 1 interferon (IFN) pathway is important for host control of HIV and…”
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Sepsis: Personalized Medicine Utilizing 'Omic' Technologies-A Paradigm Shift? by Itenov, Theis Skovsgaard, Murray, Daniel D, Jensen, Jens Ulrik Stæhr

“…Sepsis has over the years proven a considerable challenge to physicians and researchers. Numerous pharmacological and non-pharmacological interventions have…”
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Metabolic Profiling Early Post-Allogeneic Haematopoietic Cell Transplantation in the Context of CMV Infection by Rasmussen, Kirstine K, dos Santos, Quenia, MacPherson, Cameron Ross, Zucco, Adrian G, Gjærde, Lars Klingen, Ilett, Emma E, Lodding, Isabelle, Helleberg, Marie, Lundgren, Jens D, Nielsen, Susanne D, Brix, Susanne, Sengeløv, Henrik, Murray, Daniel D

“…Immune dysfunction resulting from allogeneic haematopoietic stem cell transplantation (aHSCT) predisposes one to an elevated risk of cytomegalovirus (CMV)…”
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Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study by Murray, Daniel D, Suzuki, Kazuo, Law, Matthew, Trebicka, Jonel, Neuhaus, Jacquie, Wentworth, Deborah, Johnson, Margaret, Vjecha, Michael J, Kelleher, Anthony D, Emery, Sean

“…The use of anti-retroviral therapy (ART) has dramatically reduced HIV-1 associated morbidity and mortality. However, HIV-1 infected individuals have increased…”
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Biomarkers of Clot Activation and Degradation and Risk of Future Major Cardiovascular Events in Acute Exacerbation of COPD: A Cohort Sub-Study in a Randomized Trial Population by Kamstrup, Peter, Sand, Jannie Marie Bülow, Ulrik, Charlotte Suppli, Janner, Julie, Rønn, Christian Philip, Rønnow, Sarah Rank, Leeming, Diana Julie, Jensen, Sidse Graff, Wilcke, Torgny, Mathioudakis, Alexander G, Miravitlles, Marc, Lapperre, Therese, Bendstrup, Elisabeth, Frikke-Schmidt, Ruth, Murray, Daniel D, Itenov, Theis, Bossios, Apostolos, Nielsen, Susanne Dam, Vestbo, Jørgen, Biering-Sørensen, Tor, Karsdal, Morten, Jensen, Jens-Ulrik, Sivapalan, Pradeesh

“…Cardiovascular diseases are common in patients with chronic obstructive pulmonary disease (COPD). Clot formation and resolution secondary to systemic…”
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SARS-CoV-2 Delta and Omicron community transmission networks as added value to contact tracing by Murray, John M., Murray, Daniel D., Schvoerer, Evelyne, Akand, Elma H.

“…Calculations of SARS-CoV-2 transmission networks at a population level have been limited. Networks that estimate infections between individuals and whether…”
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miRNAs and HIV: unforeseen determinants of host-pathogen interaction by Swaminathan, Sanjay, Murray, Daniel D., Kelleher, Anthony D.

“…Summary Our understanding of the complexity of gene regulation has significantly improved in the last decade as the role of small non‐coding RNAs, called…”
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Differential regulation of the Let-7 family of microRNAs in CD4+ T cells alters IL-10 expression by Swaminathan, Sanjay, Suzuki, Kazuo, Seddiki, Nabila, Kaplan, Warren, Cowley, Mark J, Hood, Chantelle L, Clancy, Jennifer L, Murray, Daniel D, Méndez, Catalina, Gelgor, Linda, Anderson, Ben, Roth, Norman, Cooper, David A, Kelleher, Anthony D

“…MicroRNAs (miRNAs) are ∼22-nt small RNAs that are important regulators of mRNA turnover and translation. Recent studies have shown the importance of the miRNA…”
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Association between ten-eleven methylcytosine dioxygenase 2 genetic variation and viral load in people with HIV by Murray, Daniel D., Grund, Birgit, MacPherson, Cameron R., Ekenberg, Christina, Zucco, Adrian G., Reekie, Joanne, Dominguez-Dominguez, Lourdes, Leung, Preston, Fusco, Dahlene, Gras, Julien, Gerstoft, Jan, Helleberg, Marie, Borges, Álvaro H., Polizzotto, Mark N., Lundgren, Jens D.

“…Identifying genetic factors that influence HIV-pathogenesis is critical for understanding disease pathways. Previous studies have suggested a role for the…”
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Gut microbiome comparability of fresh-frozen versus stabilized-frozen samples from hospitalized patients using 16S rRNA gene and shotgun metagenomic sequencing by Ilett, Emma E., Jørgensen, Mette, Noguera-Julian, Marc, Daugaard, Gedske, Murray, Daniel D., Helleberg, Marie, Paredes, Roger, Lundgren, Jens, Sengeløv, Henrik, MacPherson, Cameron

“…Collection of faecal samples for microbiome analysis in acutely sick patients is logistically difficult, particularly if immediate freezing is required (i.e…”
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Associations of the gut microbiome and clinical factors with acute GVHD in allogeneic HSCT recipients by Ilett, Emma E., Jørgensen, Mette, Noguera-Julian, Marc, Nørgaard, Jens Christian, Daugaard, Gedske, Helleberg, Marie, Paredes, Roger, Murray, Daniel D., Lundgren, Jens, MacPherson, Cameron, Reekie, Joanne, Sengeløv, Henrik

“…Acute graft-versus-host disease (aGVHD) is a leading cause of transplantation-related mortality after allogeneic hematopoietic stem cell transplantation…”
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Human Immunotypes Impose Selection on Viral Genotypes Through Viral Epitope Specificity by Gabrielaite, Migle, Bennedbæk, Marc, Zucco, Adrian G, Ekenberg, Christina, Murray, Daniel D, Kan, Virginia L, Touloumi, Giota, Vandekerckhove, Linos, Turner, Dan, Neaton, James, Lane, H Clifford, Safo, Sandra, Arenas-Pinto, Alejandro, Polizzotto, Mark N, Günthard, Huldrych F, Lundgren, Jens D, Marvig, Rasmus L

“…Abstract Background Understanding the genetic interplay between human hosts and infectious pathogens is crucial for how we interpret virulence factors. Here,…”
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Circulating miR-122 and miR-200a as biomarkers for fatal liver disease in ART-treated, HIV-1-infected individuals by Murray, Daniel D., Suzuki, Kazuo, Law, Matthew, Trebicka, Jonel, Neuhaus Nordwall, Jacquie, Johnson, Margaret, Vjecha, Michael J., Kelleher, Anthony D., Emery, Sean

“…Liver disease is one of the main contributors to the increased levels of morbidity and mortality seen in the HIV-1-infected, ART-treated population…”
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The role of microRNAs in HIV-1 pathogenesis and therapy by SWAMINATHAN, Sanjay, MURRAY, Daniel D, KELLEHER, Anthony D

“…There has been a paradigm shift in our understanding of how protein regulation occurs within mammalian cells in the last 15 years. Our current understanding is…”
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Evaluating Primary Endpoints for COVID-19 Therapeutic Trials to Assess Recovery by Douin, David J, Siegel, Lianne, Grandits, Greg, Phillips, Andrew, Aggarwal, Neil R, Baker, Jason, Brown, Samuel M, Chang, Christina C, Goodman, Anna L, Grund, Birgit, Higgs, Elizabeth S, Hough, Catherine L, Murray, Daniel D, Paredes, Roger, Parmar, Mahesh, Pett, Sarah, Polizzotto, Mark N, Sandkovsky, Uriel, Self, Wesley H, Young, Barnaby E, Babiker, Abdel G, Davey, Victoria J, Kan, Virginia, Gelijns, Annetine C, Matthews, Gail, Thompson, B Taylor, Lane, H Clifford, Neaton, James D, Lundgren, Jens D, Ginde, Adit A

“…Uncertainty regarding the natural history of coronavirus disease (COVID-19) led to difficulty in efficacy endpoint selection for therapeutic trials. Capturing…”
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The association of human leukocyte antigen alleles with clinical disease progression in HIV-positive cohorts with varied treatment strategies by Ekenberg, Christina, Reekie, Joanne, Zucco, Adrian G., Murray, Daniel D., Sharma, Shweta, Macpherson, Cameron R., Babiker, Abdel, Kan, Virginia, Lane, H. Clifford, Neaton, James D., Lundgren, Jens D.

“…The Strategic Timing of AntiRetroviral Treatment (START) and Strategies for Management of Antiretroviral Therapy (SMART) trials demonstrated that ART can…”
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