Search Results - "Murray, Ana P"

Withanolide Profile and Acetylcholinesterase Inhibitory Activity of Two Argentinean Jaborosa Species by Alza, Natalia P, Pferschy-Wenzig, Eva M, Kunert, Olaf, Murray, Ana P

“…Acetylcholinesterase (AChE) inhibitors are still an important option for managing symptoms of mild to moderate Alzheimer's disease. In this study, we aimed to…”
Get more information

New Synthetic Caffeine Analogs as Modulators of the Cholinergic System by Fabiani, Camila, Biscussi, Brunella, Munafó, Juan P, Murray, Ana P, Corradi, Jeremías, Antollini, Silvia S

“…Alzheimer's disease is a multifactorial neurodegenerative disorder. Since cholinergic deficit is a major factor in this disease, two molecular targets for its…”
Get full text

Polymeric nanoparticles improve lethal and sublethal effects of essential oils and pyrethroids toward the rice weevil and the cigarette beetle by Yeguerman, Cristhian A., Jesser, Emiliano N., Gili, Valeria, Rodriguez, Silvana, Santillán, Graciela, Murray, Ana P., González, Jorge O. Werdin

“…The rice weevil ( Sitophilus oryzae L.) and the cigarette beetle ( Lasioderma serricorne F.) are primary and secondary insect pests that cause significant…”
Get full text

Essential oils loaded on polymeric nanoparticles: bioefficacy against economic and medical insect pests and risk evaluation on terrestrial and aquatic non-target organisms by Yeguerman, Cristhian A., Urrutia, Rodrigo I., Jesser, Emiliano N., Massiris, Manlio, Delrieux, Claudio A., Murray, Ana P., González, Jorge O. Werdin

“…This paper introduces the lethal, sublethal, and ecotoxic effects of peppermint and palmarosa essential oils (EOs) and their polymeric nanoparticles (PNs). The…”
Get full text

Alkynyl and β-ketophosphonates: Selective and potent butyrylcholinesterase inhibitors by Cavallaro, Valeria, Moglie, Yanina F., Murray, Ana P., Radivoy, Gabriel E.

“…[Display omitted] •A series of phosphonates were evaluated for their AChE and BChE inhibitory activities.•IC50 values were determined and structure-activity…”
Get full text

Design, synthesis and evaluation of cholinesterase hybrid inhibitors using a natural steroidal alkaloid as precursor by Borioni, José L., Cavallaro, Valeria, Murray, Ana P., Peñéñory, Alicia B., Puiatti, Marcelo, García, Manuela E.

“…[Display omitted] •Synthesis of cholinesterase inhibitors, fusing tacrine and the alkaloid solanocapsine.•Inhibition against AChE and BuChE enzymes at nM range…”
Get full text

Cativic acid-caffeic acid hybrid exerts cytotoxic effects and induces apoptotic death in human neuroblastoma cells by Alza, Natalia P., Murray, Ana P., Salvador, Gabriela A.

“…The development of hybrids from natural products is a promising strategy for drug discovery. In cancer therapy, there is a need to discover novel agents that…”
Get full text

An activity prediction model for steroidal and triterpenoidal inhibitors of Acetylcholinesterase enzyme by Borioni, José L., Cavallaro, Valeria, Pierini, Adriana B., Murray, Ana P., Peñéñory, Alicia B., Puiatti, Marcelo, García, Manuela E.

“…Nowadays, the importance of computational methods in the design of therapeutic agents in a more efficient way is indisputable. Particularly, these methods have…”
Get full text

Synthesis and acetylcholinesterase inhibitory activity of polyhydroxylated sulfated steroids: Structure/activity studies by Richmond, Victoria, Murray, Ana P., Maier, Marta S.

“…[Display omitted] •Disulfated and trisulfated steroids were synthesized starting from cholesterol.•Acetylcholinesterase inhibitory activity of the compounds…”
Get full text

Solanocapsine derivatives as potential inhibitors of acetylcholinesterase: Synthesis, molecular docking and biological studies by García, Manuela E., Borioni, José L., Cavallaro, Valeria, Puiatti, Marcelo, Pierini, Adriana B., Murray, Ana P., Peñéñory, Alicia B.

“…[Display omitted] •Solanocapsine, a steroidal alkaloid was isolated from Solanum pseudocapsicum L.•A set of solanocapsine chemical derivatives was…”
Get full text

Clinanthus microstephium, an Amaryllidaceae Species with Cholinesterase Inhibitor Alkaloids: Structure−Activity Analysis of Haemanthamine Skeleton Derivatives by Adessi, Tonino G., Borioni, José L., Pigni, Natalia B., Bastida, Jaume, Cavallaro, Valeria, Murray, Ana P., Puiatti, Marcelo, Oberti, Juan C., Leiva, Segundo, Nicotra, Viviana E., Garcia, Manuela E.

“…Plants of the Amaryllidaceae family are well‐known (not only) for their ornamental value but also for the alkaloids that they produce. In this report, the…”
Get full text

Composition and biological activity of essential oils from Labiatae against Nezara viridula (Hemiptera: Pentatomidae) soybean pest by Werdin González, Jorge O, Gutiérrez, María M, Murray, Ana P, Ferrero, Adriana A

“…BACKGROUND: Plant essential oils have been recognised as an important natural source of insecticide. This study analysed the chemical constituents and…”
Get full text

Alkaloids from Habranthus tubispathus and H. jamesonii, two amaryllidaceae with acetyl- and butyrylcholinesterase inhibition activity by Cavallaro, Valeria, Alza, Natalia P, Murray, María G, Murray, Ana P

“…Alzheimer's disease (AD) is a neurodegenerative disorder associated with memory impairment and cognitive deficit. Most of the drugs currently available for the…”
Get more information

Inhibition of NO Production by Grindelia argentina and Isolation of Three New Cytotoxic Saponins by Alza, Natalia P., Pferschy-Wenzig, Eva-Maria, Ortmann, Sabine, Kretschmer, Nadine, Kunert, Olaf, Rechberger, Gerald N., Bauer, Rudolf, Murray, Ana P.

“…A bioassay‐guided phytochemical analysis of the ethanolic extract of Grindelia argentina Deble & Oliveira‐Deble (Asteraceae) allowed the isolation of a known…”
Get full text

Synthesis and acetylcholinesterase inhibitory activity of 2β,3α-disulfoxy-5α-cholestan-6-one by Richmond, Victoria, Santos, Gustavo A. Garrido, Murray, Ana P., Maier, Marta S.

“…► 2β,3α-dihydroxy-5α-cholestan-6-one disulfate was synthesized from cholesterol. ► The disulfated steroid showed acetylcholinesterase inhibitory activity. ►…”
Get full text

Antioxidant activity and chemical composition of essential oil from Atriplex undulata by Rodriguez, Silvana A, Murray, Ana P

“…The essential oil from aerial parts (stems and leaves) of Atriplex undulata (Moq) D. Dietr. (Chenopodiaceae) has been studied for its in vitro antioxidant…”
Get more information

Biological activity of essential oils from Aloysia polystachya and Aloysia citriodora (Verbenaceae) against the soybean pest Nezara viridula (Hemiptera: Pentatomidae) by Werdin González, Jorge O, Gutiérrez, Maria M, Murray, Ana P, Ferrero, Adriana A

“…The objective of the current study was to determine the chemical constituents, ovicidal activity, fumigant, contact toxicity and repellent effects of essential…”
Get more information

Patagonicoside A: a novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus by Murray, Ana P, Muniaı́n, Claudia, Seldes, Alicia M, Maier, Marta S

“…A new triterpene glycoside, patagonicoside A ( 1), has been isolated from the sea cucumber Psolus patagonicus and its structure has been elucidated by 1D and…”
Get full text

Antioxidant Metabolites from Limonium brasiliense (Boiss.) Kuntze by Murray, Ana P., Rodriguez, Silvana, Frontera, María A., Tomas, María A., Mulet, María C.

“…A free radical scavenging activity guided fractionation of the polar extract from roots of Limonium brasiliense (Plumbaginaceae) led to the isolation of five…”
Get full text

Acetylcholinesterase inhibition and antioxidant activity of essential oils from Schinus areira L. and Schinus longifolia (Lindl.) Speg by Murray, Ana P, Gurovic, Maria S Vela, Rodriguez, Silvana A, Murray, María G, Ferrero, Adriana A

“…The essential oils of Schinus areira L. and S. longifolia (Lindl.) Speg. (Anacardiaceae) have been studied for their in vitro anti-acetylcholinesterase and…”
Get more information